BBa_C2004
1
BBa_C2004
Homodimeric zinc finger
2006-10-20T11:00:00Z
2015-08-31T04:07:25Z
It was derived from BBa_C2002.
This is protein based on Scot Wolfe's Zif268-GCN4 homodimeric zinc finger protein. It is a fusion of fingers 2 and 3 of Zif268 (mouse) and the leucine zipper domain of GCN4 (yeast). Scot optimized the linker between the zinc finger domain and the leucine zipper domain to increase affinity of the homodimer for the 12bp operator. It is codon optimized for E. coli.
false
false
_41_
0
126
70
Not in stock
false
It is codon optimized for E. coli.
false
Reshma Shetty
annotation1903894
1
start codon
range1903894
1
1
3
annotation1903900
1
double stop codon
range1903900
1
283
288
annotation1903898
1
domain linker
range1903898
1
151
177
annotation1903895
1
Zif268.GCN4(-2) codon optimized
range1903895
1
1
288
annotation1903896
1
hexaHis tag
range1903896
1
265
282
annotation1903899
1
GCN4 homodimerization domain
range1903899
1
178
264
annotation1903897
1
Finger 3 of Zif268
range1903897
1
91
150
annotation1903893
1
Finger 2 of Zif268
range1903893
1
4
90
BBa_C2004_sequence
1
atgaaaccgttccagtgccgtatctgcatgcgtaacttctcccgttccgaccacctgaccacccacatccgtacccacaccggtgaaaaaccgttcgcttgcgacatctgcggtcgtaaattcgctcgttccgacgaacgtaaacgtcaccgtgatattcagcatattctgccgattctggaagacaaagttgaagaactgctgtccaaaaactaccacctggaaaacgaagttgctcgtctgaaaaaactggttggtgaacgtcatcaccatcaccatcactaataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z