BBa_J100065
1
BBa_J100065
Synthetic Riboswitch
2012-06-10T11:00:00Z
2015-08-31T04:08:22Z
http://www.ncbi.nlm.nih.gov/pubmed?term=Synthetic%20Riboswitches%20That%20Induce%20Gene%20Expression%20in%20Diverse%20Bacterial%20Species
This part is a synthetic riboswitch that can be used in E. coli. In the presence of theophylline, the expression of the gene of interest is induced, but in the absence of theophylline, very little transcription takes place. This part contains a modified T5 promoter, which, in the absence of cymR, acts as a strong constitutive promoter. The ribosomal binding site is contained in the riboswitch.
false
false
_578_
0
10704
9
Not in stock
false
Because the riboswitch must be directly beside the gene of interest (the start codon is used in the folding of the riboswitch), we added a BsaI recognition site. This allows the riboswitch to be connected directly to a gene of interest using the Golden Gate Assembly method (if the first nucleotide after the start codon of the gene of interest is a C, we made it for use with superfolder GFP).
false
Rebecca Evans
annotation2176244
1
BBa suffix
range2176244
1
193
213
annotation2176236
1
lac operator
range2176236
1
76
96
annotation2176235
1
T5 promoter
range2176235
1
23
75
annotation2176240
1
Riboswitch
range2176240
1
125
184
annotation2176234
1
BBa prefix
range2176234
1
1
22
annotation2176241
1
RBS
range2176241
1
168
172
annotation2176242
1
Start
range2176242
1
182
184
annotation2176243
1
GGA prefix ATGC sticky word
range2176243
1
182
192
annotation2176239
1
KpnI site
range2176239
1
119
124
annotation2176237
1
scar
range2176237
1
97
102
annotation2176238
1
constant sequence
range2176238
1
104
118
BBa_J100065_sequence
1
gaattcgcggccgcttctagagaaatcataaaaaatttatttgctttgtgagcggataacaattataatagattcaattgtgagcggataacaattactagagatacgactcactataggtaccggtgataccagcatcgtcttgatgcccttggcagcaccctgctaaggtaacaacaagatgctgagacctactagtagcggccgctgcag
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z