BBa_J100263
1
BBa_J100263
RS10 (Wachsmuth et al. 2013) in J119361
2016-06-08T11:00:00Z
2016-06-13T08:03:20Z
The RS10 riboswitch was developed by Wachsumth et al. for their 2013 paper "De novo design of a synthetic riboswitch that regulates transcription termination." The RS10 riboswitch was inserted into J119361 via Golden Gate Assembly and replaced the GFP cassette that had occupied this part.
J11263 reports the functionality of the RS10 riboswitch from Wachsumth et al. 2013 by its expression of the reporter RFP gene. The RS10 riboswitch is a theophylline-binding transcriptional riboswitch that turns on gene expression in the presence of theophylline. In the presence of theophylline, cells containing this part should fluoresce red. In the absence of theophylline, cells containing this part should not fluoresce.
false
false
_578_
28825
28825
9
false
The design of this sequence required the insertion of the RS10 riboswitch upstream of the reporter RFP gene. Such a design was made possible by the replacement of the GFP cassette in J119361 with the RS10 riboswitch via Golden Gate Assembly.
false
Owen Koucky
annotation2480085
1
BD18 C Dog RBS
range2480085
1
113
197
annotation2480084
1
RS10
range2480084
1
41
108
annotation2480083
1
P5 promoter
range2480083
1
1
36
annotation2480086
1
RFP protein half
range2480086
1
198
878
BBa_J100263_sequence
1
ttgacaattaatcatccggctcgtaatttatgtggacgacaagtgataccagcatcgtcttgatgcccttggcagcacttcagaaatctctgaagtgctgttttttttgcgggggcccaagttcacttaaaaaggagatcaacaatgaaagcaattttcgtactgaaacatcttaatcatgcgacggagcgtttctaatggcttcctccgaagatgttatcaaagagttcatgcgtttcaaagttcgtatggaaggttccgttaacggtcacgagttcgaaatcgaaggtgaaggtgaaggtcgtccgtacgaaggtacccagaccgctaaactgaaagttaccaaaggtggtccgctgccgttcgcttgggacatcctgtccccgcagttccagtacggttccaaagcttacgttaaacacccggctgacatcccggactacctgaaactgtccttcccggaaggtttcaaatgggaacgtgttatgaacttcgaagatggtggtgttgttaccgttacccaggactcctccctgcaagacggtgagttcatctacaaagttaaactgcgtggtaccaacttcccgtccgacggtccggttatgcagaaaaaaaccatgggttgggaagcttccaccgaacgtatgtacccggaagatggtgctctgaaaggtgaaatcaaaatgcgtctgaaactgaaagacggtggtcactacgacgctgaagttaaaaccacctacatggctaaaaaaccggttcagctgccgggtgcttacaaaaccgacatcaaactggacatcacctcccacaacgaagattacaccatcgttgaacagtacgaacgtgctgaaggtcgtcactccaccggtgcttaataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z