BBa_J10064
1
BBa_J10064
Lux Operon Vibrio fischeri from part K325909
2012-01-10T12:00:00Z
2015-08-31T04:08:24Z
from K325909 with pBad removed, synthesized de novo
This page described the lux operon from Vibrio fischeri. To relieve LuxR control we placed Lux C, D, A, B, E under a promoter of your choice. A more complete description can be found on the [[http://2010.igem.org/Team:Cambridge Cambridge iGEM 2010] website.
This Bacterial lux operons encodes five enzymes involved in the light-generating pathway. LuxA and LuxB encode the two subunits of the bacterial luciferase, while the products of LuxC, LuxD and LuxE synthesise the substrate for the light emitting reaction, tetradecanal. The exact function of LuxG is unknown, and it appears to be non-essential for light emission, but its presence increases light output.
In nature, the lux genes appear to be repressed by the nucleoid protein, H-NS, and occur under quorum sensing control. We removed the natural quorum sensing control to facilitate use of the part in biosensors under different regulatory inputs.
As of October 2010 [http://2010.igem.org/Team:Cambridge Cambridge] believe this is the first and only BioBrick to emit light in normal E. coli strains without the addition of any external substrate.
false
true
_578_120_
0
201
61
It's complicated
false
removed pBad to make it more usable for different purposes
false
Malcolm Campbell
annotation2169585
1
endogenous #6?
range2169585
1
5705
5709
annotation2169578
1
luxD
range2169578
1
1465
2369
annotation2169576
1
luxC
range2169576
1
11
1450
annotation2169583
1
endogenous #5
range2169583
1
4565
4573
annotation2169575
1
endogenous #1
range2169575
1
1
10
annotation2169582
1
luxB
range2169582
1
3522
4502
annotation2169580
1
luxA
range2169580
1
2419
3483
annotation2169584
1
luxE
range2169584
1
4577
5713
annotation2169579
1
endogenous #3
range2169579
1
2404
2413
annotation2169586
1
uxG
range2169586
1
5717
6427
annotation2169577
1
endogenous #2
range2169577
1
1451
1462
annotation2169581
1
endogenous #4
range2169581
1
3507
3518
BBa_J10064_sequence
1
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igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z