BBa_R0065
1
cI+luxR
Promoter (lambda cI and luxR regulated -- hybrid)
2003-01-31T12:00:00Z
2015-05-08T01:14:15Z
Released HQ 2013
cI repressor negatively regulates this promoter and LuxR activates its transcription.The effect of cI is dominant over LuxR. This part is based on the LuxR and cI repressor regulated hybrid promoter designed and tested by Ron Weiss. It requires the binding of two cI repressor dimers for maximal repression and contains two cI repressor binding sites namely, OR1 and OR2. This promoter is leaky in the sense that 'some' transcription is seen in the absence of both cI and LuxR. </P> <P> </P> <table width="75%" border="1"> <tr> <td><strong>LuxI</strong></td> <td><strong>cI</strong></td> <td><strong>activity of promoter</strong></td> </tr> <tr> <td>+</td> <td>+</td> <td>zero</td> </tr> <tr> <td>+</td> <td>-</td> <td>maximum</td> </tr> <tr> <td>-</td> <td>+</td> <td>zero</td> </tr> <tr> <td>-</td> <td>-</td> <td>leaky (no quantitative information)</td> </tr> </table> <P> </P>
false
false
_1_
0
24
7
In stock
false
<P> <P>This part was designed based on the LuxR and cI repressor regulated hybrid promoter tested by Ron Weiss and the LuxR-LuxICDABE sequence annotated by Tom Knight <genbank>AF170104</genbank>. <P>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr
annotation1986777
1
OR2 cI
range1986777
1
57
73
annotation1986775
1
Lux Box
range1986775
1
6
25
annotation1986779
1
-35
range1986779
1
71
76
annotation1986781
1
-10
range1986781
1
94
97
annotation1986778
1
lux p(R) start
range1986778
1
58
58
annotation1986776
1
-10
range1986776
1
47
52
annotation1986780
1
OR1 cI
range1986780
1
81
97
annotation1986774
1
BBa_R0065
range1986774
1
1
97
BBa_B0025
1
BBa_B0025
double terminator (B0015), reversed
2003-12-02T12:00:00Z
2015-08-31T04:07:20Z
-- No description --
false
true
_1_
0
24
7
In stock
false
true
Caitlin Conboy
annotation369702
1
B0012
range369702
1
1
41
annotation369703
1
B0010
range369703
1
50
129
BBa_E0040
1
GFP
green fluorescent protein derived from jellyfish Aequeora victoria wild-type GFP (SwissProt: P42212
2004-09-29T11:00:00Z
2016-01-26T02:09:38Z
Released HQ 2013
GFP (mut3b) [note that this part does not have a barcode]
false
true
_11_1_
4206
61
7
In stock
false
true
jcbraff
annotation1934520
1
GFP protein
range1934520
1
1
720
BBa_B0032
1
BBa_B0032
RBS.3 (medium) -- derivative of BBa_0030
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
Weak1 RBS based on Ron Weiss thesis. Strength is considered relative to <bb_part>BBa_B0030</bb_part>, <bb_part>BBa_B0031</bb_part>, <bb_part>BBa_B0033</bb_part>.
false
true
_41_44_48_46_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix ("RBS-2" in figure 4-14 of thesis). <P>
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation7027
1
BBa_B0032
range7027
1
1
13
annotation1710
1
RBS
range1710
1
7
10
annotation1709
1
RBS-3\Weak
range1709
1
1
13
BBa_C0053
1
c2 P22
c2 repressor from Salmonella phage P22 (+LVA)
2003-01-31T12:00:00Z
2015-08-31T04:07:23Z
Bacteriophage P22
Released HQ 2013
The P22 c2 repressor protein coding sequence is a 720 base-pair sequence with the standard RBS-compatible BioBrick prefix and the standard BioBrick suffix sections on its ends. It binds to the P22 c2 regulatory sequence, BBa_R0053. The sequence contains a LVA tag for faster degredation.</p>
false
false
_1_
0
24
7
In stock
false
References (unparsed) here: <p>Vander Byl,C. and Kropinski,A.M. <em>Sequence of the genome of Salmonella bacteriophage P22</em><br> J. Bacteriol. 182 (22), 6472-6481 (2000) <P> References (unparsed) here: <p>Vander Byl,C. and Kropinski,A.M. <em>Sequence of the genome of Salmonella bacteriophage P22</em><br> J. Bacteriol. 182 (22), 6472-6481 (2000) <P><P>
true
Maia Mahoney
annotation2213993
1
Help:Barcodes
range2213993
1
688
712
annotation1751
1
stop
range1751
1
682
687
annotation7036
1
BBa_C0053
range7036
1
1
687
annotation1747
1
cII p22
range1747
1
1
648
annotation1750
1
LVA
range1750
1
649
681
BBa_I9200
1
cI
cI lambda
2004-01-27T12:00:00Z
2015-08-31T04:08:11Z
lambda bacteriophage
false
false
_1_
0
24
7
It's complicated
false
cI sequence slightly different from part C0051. NCBI locus: NC_001416
false
crackdots
annotation2214008
1
Help:Barcodes
range2214008
1
718
742
annotation302655
1
cI lambda
range302655
1
1
717
BBa_J11002
1
BBa_J11002
improved pulse generator/PI controller
2005-06-20T11:00:00Z
2015-08-31T04:08:25Z
input is luxI
direct negative feedback by CI, integral feedback through p22 CII (in concert with part BBa_J1103). Generates bursts of gfp activity in response to step increases in luxI concentration. Should exhibit perfect(?!) adaptation.
false
false
_38_
0
337
38
Not in stock
false
false
ingalls
component2226129
1
BBa_B0032
component2226143
1
BBa_B0032
component2226149
1
BBa_B0025
component2226120
1
BBa_R0065
component2226133
1
BBa_I9200
component2226146
1
BBa_E0040
component2226135
1
BBa_B0032
component2226138
1
BBa_C0053
annotation2226135
1
BBa_B0032
range2226135
1
875
887
annotation2226138
1
BBa_C0053
range2226138
1
894
1580
annotation2226149
1
BBa_B0025
range2226149
1
2361
2489
annotation2226146
1
BBa_E0040
range2226146
1
1633
2352
annotation2226129
1
BBa_B0032
range2226129
1
106
118
annotation2226120
1
BBa_R0065
range2226120
1
1
97
annotation2226143
1
BBa_B0032
range2226143
1
1614
1626
annotation2226133
1
BBa_I9200
range2226133
1
125
866
BBa_J11002_sequence
1
taagcacctgtaggatcgtacaggtttacgcaagaaaatggtttgttatagtcgaataacaccgtgcgtgttgactattttacctctggcggtgatatactagagtcacacaggaaagtactagatgagcactaaaaagaaaccacttactcaagagcagttagaggacgcccgtcgcttaaaagccatttatgaaaaaaagaaaaatgaattaggcctttcccaggaatcagtcgccgacaagatggggatggggcagtcgggcgttggtgctctttttaatggcatcaatgcccttaatgcttataacgcggccctcttagccaaaattttgaaagttagcgttgaagaatttagcccttcgatcgcgcgagaaatctacgagatgtatgaagcagttagtatgcagccgtcgttacgaagtgagtatgagtaccctgttttttcacatgttcaggccgggatgttctcgcctgagttacgaacctttaccaaaggtgatgcagagcgatgggtaagcactaccaaaaaagcgagtgattcagccttctggttagaggttgaaggtaattccatgaccgccccaactggctccaagccaagctttcctgacggaatgcttattttggttgaccctgagcaggctgttgagccaggtgatttctgcatagcgcgattagggggtgatgagtttaccttcaagaaactgatcagggatagcggtcaggtgtttcttcaaccactaaacccacagtacccaatgatcccatgcaatgagagttgttccgttgtggggaaagttatcgctagtcagtggcctgaagagacgtttggctaataactctgatagtgctagtgtagatctctactagagtcacacaggaaagtactagatgaatacacaattgatgggtgagcgtattcgcgctcgaagaaaaaaactcaagattagacaagccgctcttggtaagatggtgggagtgtctaatgttgcaatatcgcaatgggagcgctcggagactgagccaaatggggagaacctgttggcactttcgaaggctcttcagtgctcccctgactatttgctgaaaggagatttaagccagacaaacgttgcctatcatagtaggcatgagccaagaggatcataccctcttatcagttgggtaagcgcagggcaatggatggaagctgtagaaccttatcacaagcgcgcgatagagaactggcacgacaccactgtagattgttcagaagattcattttggcttgatgtccaaggtgactctatgacagcaccggcagggttaagcattccagaaggaatgataattctggttgatcccgaagtcgaaccaagaaacggcaagctggttgttgcaaaattagaaggtgaaaacgaggccacattcaaaaaattagttatggatgcaggccgaaagtttttaaaaccattaaacccacaatatccgatgatagaaatcaacggaaactgcaaaatcattggcgtagttgttgacgcaaaactcgcaaatcttccagctgcaaacgacgaaaactacgctttagtagcttaataacactgatagtgctagtgtagatcactactagagtcacacaggaaagtactagatgcgtaaaggagaagaacttttcactggagttgtcccaattcttgttgaattagatggtgatgttaatgggcacaaattttctgtcagtggagagggtgaaggtgatgcaacatacggaaaacttacccttaaatttatttgcactactggaaaactacctgttccatggccaacacttgtcactactttcggttatggtgttcaatgctttgcgagatacccagatcatatgaaacagcatgactttttcaagagtgccatgcccgaaggttatgtacaggaaagaactatatttttcaaagatgacgggaactacaagacacgtgctgaagtcaagtttgaaggtgatacccttgttaatagaatcgagttaaaaggtattgattttaaagaagatggaaacattcttggacacaaattggaatacaactataactcacacaatgtatacatcatggcagacaaacaaaagaatggaatcaaagttaacttcaaaattagacacaacattgaagatggaagcgttcaactagcagaccattatcaacaaaatactccaattggcgatggccctgtccttttaccagacaaccattacctgtccacacaatctgccctttcgaaagatcccaacgaaaagagagaccacatggtccttcttgagtttgtaacagctgctgggattacacatggcatggatgaactatacaaataataatactagagtataaacgcagaaaggcccacccgaaggtgagccagtgtgactctagtagagagcgttcaccgacaaacaacagataaaacgaaaggcccagtctttcgactgagcctttcgttttatttgatgcctgg
BBa_B0032_sequence
1
tcacacaggaaag
BBa_E0040_sequence
1
atgcgtaaaggagaagaacttttcactggagttgtcccaattcttgttgaattagatggtgatgttaatgggcacaaattttctgtcagtggagagggtgaaggtgatgcaacatacggaaaacttacccttaaatttatttgcactactggaaaactacctgttccatggccaacacttgtcactactttcggttatggtgttcaatgctttgcgagatacccagatcatatgaaacagcatgactttttcaagagtgccatgcccgaaggttatgtacaggaaagaactatatttttcaaagatgacgggaactacaagacacgtgctgaagtcaagtttgaaggtgatacccttgttaatagaatcgagttaaaaggtattgattttaaagaagatggaaacattcttggacacaaattggaatacaactataactcacacaatgtatacatcatggcagacaaacaaaagaatggaatcaaagttaacttcaaaattagacacaacattgaagatggaagcgttcaactagcagaccattatcaacaaaatactccaattggcgatggccctgtccttttaccagacaaccattacctgtccacacaatctgccctttcgaaagatcccaacgaaaagagagaccacatggtccttcttgagtttgtaacagctgctgggattacacatggcatggatgaactatacaaataataa
BBa_C0053_sequence
1
atgaatacacaattgatgggtgagcgtattcgcgctcgaagaaaaaaactcaagattagacaagccgctcttggtaagatggtgggagtgtctaatgttgcaatatcgcaatgggagcgctcggagactgagccaaatggggagaacctgttggcactttcgaaggctcttcagtgctcccctgactatttgctgaaaggagatttaagccagacaaacgttgcctatcatagtaggcatgagccaagaggatcataccctcttatcagttgggtaagcgcagggcaatggatggaagctgtagaaccttatcacaagcgcgcgatagagaactggcacgacaccactgtagattgttcagaagattcattttggcttgatgtccaaggtgactctatgacagcaccggcagggttaagcattccagaaggaatgataattctggttgatcccgaagtcgaaccaagaaacggcaagctggttgttgcaaaattagaaggtgaaaacgaggccacattcaaaaaattagttatggatgcaggccgaaagtttttaaaaccattaaacccacaatatccgatgatagaaatcaacggaaactgcaaaatcattggcgtagttgttgacgcaaaactcgcaaatcttccagctgcaaacgacgaaaactacgctttagtagcttaataacactgatagtgctagtgtagatcac
BBa_R0065_sequence
1
taagcacctgtaggatcgtacaggtttacgcaagaaaatggtttgttatagtcgaataacaccgtgcgtgttgactattttacctctggcggtgata
BBa_I9200_sequence
1
atgagcactaaaaagaaaccacttactcaagagcagttagaggacgcccgtcgcttaaaagccatttatgaaaaaaagaaaaatgaattaggcctttcccaggaatcagtcgccgacaagatggggatggggcagtcgggcgttggtgctctttttaatggcatcaatgcccttaatgcttataacgcggccctcttagccaaaattttgaaagttagcgttgaagaatttagcccttcgatcgcgcgagaaatctacgagatgtatgaagcagttagtatgcagccgtcgttacgaagtgagtatgagtaccctgttttttcacatgttcaggccgggatgttctcgcctgagttacgaacctttaccaaaggtgatgcagagcgatgggtaagcactaccaaaaaagcgagtgattcagccttctggttagaggttgaaggtaattccatgaccgccccaactggctccaagccaagctttcctgacggaatgcttattttggttgaccctgagcaggctgttgagccaggtgatttctgcatagcgcgattagggggtgatgagtttaccttcaagaaactgatcagggatagcggtcaggtgtttcttcaaccactaaacccacagtacccaatgatcccatgcaatgagagttgttccgttgtggggaaagttatcgctagtcagtggcctgaagagacgtttggctaataactctgatagtgctagtgtagatctc
BBa_B0025_sequence
1
tataaacgcagaaaggcccacccgaaggtgagccagtgtgactctagtagagagcgttcaccgacaaacaacagataaaacgaaaggcccagtctttcgactgagcctttcgttttatttgatgcctgg
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z