BBa_K1020002
1
BBa_K1020002
alkane regulatory protein ALKR
2013-08-17T11:00:00Z
2015-05-08T01:08:43Z
Acinetobacter baylyi ADP1
AlkR is a transcriptional regulator belonging to AraC/Xyls family, which could detect a broad range of alkanes and alkenes with carbon chain length from C7 to C36. It is said that AlkR is the only bioreporter that is able to detect alkane with carbon chain length greater than C18.
false
false
_1327_
0
16881
9
Not in stock
false
false
Yue Liu
annotation2331899
1
AlkR
range2331899
1
1
927
BBa_B0010
1
BBa_B0010
T1 from E. coli rrnB
2003-11-19T12:00:00Z
2015-08-31T04:07:20Z
Transcriptional terminator consisting of a 64 bp stem-loop.
false
false
_1_
0
24
7
In stock
false
true
Randy Rettberg
annotation4184
1
stem_loop
range4184
1
12
55
annotation7018
1
BBa_B0010
range7018
1
1
80
BBa_J23103
1
BBa_J23103
constitutive promoter family member
2006-08-03T11:00:00Z
2015-08-31T04:08:40Z
isolated from library of promoters
Released HQ 2013
replace later
false
true
_52_
0
483
95
In stock
true
N/A
true
John Anderson
BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_B0015
1
BBa_B0015
double terminator (B0010-B0012)
2003-07-16T11:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
Double terminator consisting of BBa_B0010 and BBa_B0012
false
true
_1_
0
24
7
In stock
false
true
Reshma Shetty
component1916610
1
BBa_B0010
component1916612
1
BBa_B0012
annotation1916610
1
BBa_B0010
range1916610
1
1
80
annotation1916612
1
BBa_B0012
range1916612
1
89
129
BBa_K1020003
1
BBa_K1020003
AlkR -PSB1C3-Low constitutive
2013-08-17T11:00:00Z
2015-05-08T01:08:43Z
Acinetobacter baylyi ADP1
AlkR is a transcriptional regulator belonging to AraC/Xyls family, which could detect a broad range of alkanes and alkenes with carbon chain length from C7 to C36. It is said that AlkR is the only bioreporter that is able to detect alkane with carbon chain length greater than C18.
The mechanism is that alkanes are presumably recognized by AlkR regulatory protein and their interaction triggered a conformation change of AlkR dimers which isomerizes the promoter-RNAP complex and lead to the activation of alkM gene.
AlkR regulatory protein includes C-terminal DNA-binding domain(CTD) for promoter binding and N-terminal domain(NTD) for inducer recognition.
Here we use a constitutive promoter for AlkR gene and in case of interference, we choose a long and strong terminator.
false
false
_1327_
0
16881
9
It's complicated
false
We use a constitutive promoter for AlkR gene and we choose a long and strong terminator to prevent interference.
false
Yue Liu
component2333539
1
BBa_B0034
component2333541
1
BBa_K1020002
component2333548
1
BBa_B0015
component2333537
1
BBa_J23103
annotation2333539
1
BBa_B0034
range2333539
1
44
55
annotation2333548
1
BBa_B0015
range2333548
1
997
1125
annotation2333537
1
BBa_J23103
range2333537
1
1
35
annotation2333541
1
BBa_K1020002
range2333541
1
62
988
BBa_K1020012
1
BBa_K1020012
Alkane Selector for intracellular alkane production
2013-09-09T11:00:00Z
2015-05-08T01:08:43Z
false
false
_1327_
0
16881
9
It's complicated
true
false
Yue Liu
component2373802
1
BBa_K1020003
component2373789
1
BBa_K1020010
annotation2373802
1
BBa_K1020003
range2373802
1
1538
2662
annotation2373789
1
BBa_K1020010
range2373789
1
1
1529
BBa_B0012
1
BBa_B0012
TE from coliphageT7
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Derived from the TE terminator of T7 bacteriophage between Genes 1.3 and 1.4 <genbank>V01146</genbank>.
Released HQ 2013
Transcription terminator for the <i>E.coli</i> RNA polymerase.
false
false
_1_
0
24
7
In stock
false
<P> <P>Suggested by Sri Kosuri and Drew Endy as a high efficiency terminator. The 5' end cutoff was placed immediately after the TAA stop codon and the 3' end cutoff was placed just prior to the RBS of Gene 1.4 (before AAGGAG).<P> Use anywhere transcription should be stopped when the gene of interest is upstream of this terminator.
false
Reshma Shetty
annotation1690
1
polya
range1690
1
28
41
annotation1686
1
T7 TE
range1686
1
8
27
annotation7020
1
BBa_B0012
range7020
1
1
41
annotation1687
1
stop
range1687
1
34
34
BBa_K1020010
1
PalkM-tetA
TetA gene under the control of PalkM
2013-09-09T11:00:00Z
2015-05-08T01:08:43Z
The parts including two core enzymes to produce alkane.
false
false
_1327_
0
16881
9
It's complicated
false
false
Yue Liu
annotation2353542
1
PalkM promoter
range2353542
1
1
178
annotation2353543
1
tetA
range2353543
1
203
1394
annotation2353556
1
terminator
range2353556
1
1400
1529
BBa_K1020010_sequence
1
agcgcgttaaaaattcttatttgagcaagagtatagaatgaggttgtagcttatacatgtgattttaggacattgacatggttgaaaatgccaaagactttgacataggttttttggacgataacgactgtttttaatatataagatggatgattatgagcagtatgaatagaggataactaggaaagaggagaaatactagatgaaatctaacaatgcgctcatcgtcatcctcggcaccgtcaccctggatgctgtaggcataggcttggttatgccggtactgccgggcctcttgcgggatatcgtccattccgacagcatcgccagtcactatggcgtgctgctagcgctatatgcgttgatgcaatttctatgcgcacccgttctcggagcactgtccgaccgctttggccgccgcccagtcctgctcgcttcgctacttggagccactatcgactacgcgatcatggcgaccacacccgtcctgtggatcctctacgccggacgcatcgtggccggcatcaccggcgccacaggtgcggttgctggcgcctatatcgccgacatcaccgatggggaagatcgggctcgccacttcgggctcatgagcgcttgtttcggcgtgggtatggtggcaggccccgtggccgggggactgttgggcgccatctccttgcatgcaccattccttgcggcggcggtgctcaacggcctcaacctactactgggctgcttcctaatgcaggagtcgcataagggagagcgtcgaccgatgcccttgagagccttcaacccagtcagctccttccggtgggcgcggggcatgactatcgtcgccgcacttatgactgtcttctttatcatgcaactcgtaggacaggtgccggcagcgctctgggtcattttcggcgaggaccgctttcgctggagcgcgacgatgatcggcctgtcgcttgcggtattcggaatcttgcacgccctcgctcaagccttcgtcactggtcccgccaccaaacgtttcggcgagaagcaggccattatcgccggcatggcggccgacgcgctgggctacgtcttgctggcgttcgcgacgcgaggctggatggccttccccattatgattcttctcgcttccggcggcatcgggatgcccgcgttgcaggccatgctgtccaggcaggtagatgacgaccatcagggacagcttcaaggatcgctcgcggctcttaccagcctaacttcgatcactggaccgctgatcgtcacggcgatttatgccgcctcggcgagcacatggaacgggttggcatggattgtaggcgccgccctataccttgtctgcctccccgcgttgcgtcgcggtgcatggagccgggccacctcgacctaaactagaccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttatat
BBa_B0010_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctc
BBa_J23103_sequence
1
ctgatagctagctcagtcctagggattatgctagc
BBa_B0034_sequence
1
aaagaggagaaa
BBa_K1020002_sequence
1
atggatgcacttagtaaaatttttgatgatattcatttaaataaatctgaatatctctatgtaaaaactcaaggagaatgggcatttcatatgcttgcccaagatgctttgattgctcacattattttaatgggttctgctcatttcacattacaggatggtacgacacaaaccgcttattcgggagatattgtgcttattccttctgggcaagctcattttgtctcaaatgatgctcagaacaaactaattgattgttccaacattcagtctttttttgatggacaccgcaatgatgccattgagttaggcacaacatcttcggatcatggtttaatttttactgtgcggagccatatcgatatgcatatgggtagccctttactcaatgctttaccatcactgatacatattcatcacgcaatgagctcaactggcccagagtggttacgcgtcggtttatattttgtggcacttgaaacccagcgtattcaaccaggacgagataaaatatttgaccacttgatgagcatcctatttatagaatgtgtccgcgatcatattgcccagcttgatgaccccaaaagctggttaactgcactcatgcatcccgaattatctaatgcgctcgcagctattcatgcttaccccgaaaaaccttggactgtagagagtttggcagatcaatgttgcatgtcacggtctaaatttgccacactttttcaaagtattgttcatgagacccctctcgcttatcttcaacaacatcgccttcgtctggccgtacagttattaaaaaccagtcagttaaatattcagcaaattgccaataaagtcggatactcctcagaaacagcttttagtcaggcatttaaacgtcaatttgaacaatctcctaaacactatcgccagcaatcatgataataa
BBa_K1020003_sequence
1
ctgatagctagctcagtcctagggattatgctagctactagagaaagaggagaaatactagatggatgcacttagtaaaatttttgatgatattcatttaaataaatctgaatatctctatgtaaaaactcaaggagaatgggcatttcatatgcttgcccaagatgctttgattgctcacattattttaatgggttctgctcatttcacattacaggatggtacgacacaaaccgcttattcgggagatattgtgcttattccttctgggcaagctcattttgtctcaaatgatgctcagaacaaactaattgattgttccaacattcagtctttttttgatggacaccgcaatgatgccattgagttaggcacaacatcttcggatcatggtttaatttttactgtgcggagccatatcgatatgcatatgggtagccctttactcaatgctttaccatcactgatacatattcatcacgcaatgagctcaactggcccagagtggttacgcgtcggtttatattttgtggcacttgaaacccagcgtattcaaccaggacgagataaaatatttgaccacttgatgagcatcctatttatagaatgtgtccgcgatcatattgcccagcttgatgaccccaaaagctggttaactgcactcatgcatcccgaattatctaatgcgctcgcagctattcatgcttaccccgaaaaaccttggactgtagagagtttggcagatcaatgttgcatgtcacggtctaaatttgccacactttttcaaagtattgttcatgagacccctctcgcttatcttcaacaacatcgccttcgtctggccgtacagttattaaaaaccagtcagttaaatattcagcaaattgccaataaagtcggatactcctcagaaacagcttttagtcaggcatttaaacgtcaatttgaacaatctcctaaacactatcgccagcaatcatgataataatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_K1020012_sequence
1
agcgcgttaaaaattcttatttgagcaagagtatagaatgaggttgtagcttatacatgtgattttaggacattgacatggttgaaaatgccaaagactttgacataggttttttggacgataacgactgtttttaatatataagatggatgattatgagcagtatgaatagaggataactaggaaagaggagaaatactagatgaaatctaacaatgcgctcatcgtcatcctcggcaccgtcaccctggatgctgtaggcataggcttggttatgccggtactgccgggcctcttgcgggatatcgtccattccgacagcatcgccagtcactatggcgtgctgctagcgctatatgcgttgatgcaatttctatgcgcacccgttctcggagcactgtccgaccgctttggccgccgcccagtcctgctcgcttcgctacttggagccactatcgactacgcgatcatggcgaccacacccgtcctgtggatcctctacgccggacgcatcgtggccggcatcaccggcgccacaggtgcggttgctggcgcctatatcgccgacatcaccgatggggaagatcgggctcgccacttcgggctcatgagcgcttgtttcggcgtgggtatggtggcaggccccgtggccgggggactgttgggcgccatctccttgcatgcaccattccttgcggcggcggtgctcaacggcctcaacctactactgggctgcttcctaatgcaggagtcgcataagggagagcgtcgaccgatgcccttgagagccttcaacccagtcagctccttccggtgggcgcggggcatgactatcgtcgccgcacttatgactgtcttctttatcatgcaactcgtaggacaggtgccggcagcgctctgggtcattttcggcgaggaccgctttcgctggagcgcgacgatgatcggcctgtcgcttgcggtattcggaatcttgcacgccctcgctcaagccttcgtcactggtcccgccaccaaacgtttcggcgagaagcaggccattatcgccggcatggcggccgacgcgctgggctacgtcttgctggcgttcgcgacgcgaggctggatggccttccccattatgattcttctcgcttccggcggcatcgggatgcccgcgttgcaggccatgctgtccaggcaggtagatgacgaccatcagggacagcttcaaggatcgctcgcggctcttaccagcctaacttcgatcactggaccgctgatcgtcacggcgatttatgccgcctcggcgagcacatggaacgggttggcatggattgtaggcgccgccctataccttgtctgcctccccgcgttgcgtcgcggtgcatggagccgggccacctcgacctaaactagaccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttatattactagagctgatagctagctcagtcctagggattatgctagctactagagaaagaggagaaatactagatggatgcacttagtaaaatttttgatgatattcatttaaataaatctgaatatctctatgtaaaaactcaaggagaatgggcatttcatatgcttgcccaagatgctttgattgctcacattattttaatgggttctgctcatttcacattacaggatggtacgacacaaaccgcttattcgggagatattgtgcttattccttctgggcaagctcattttgtctcaaatgatgctcagaacaaactaattgattgttccaacattcagtctttttttgatggacaccgcaatgatgccattgagttaggcacaacatcttcggatcatggtttaatttttactgtgcggagccatatcgatatgcatatgggtagccctttactcaatgctttaccatcactgatacatattcatcacgcaatgagctcaactggcccagagtggttacgcgtcggtttatattttgtggcacttgaaacccagcgtattcaaccaggacgagataaaatatttgaccacttgatgagcatcctatttatagaatgtgtccgcgatcatattgcccagcttgatgaccccaaaagctggttaactgcactcatgcatcccgaattatctaatgcgctcgcagctattcatgcttaccccgaaaaaccttggactgtagagagtttggcagatcaatgttgcatgtcacggtctaaatttgccacactttttcaaagtattgttcatgagacccctctcgcttatcttcaacaacatcgccttcgtctggccgtacagttattaaaaaccagtcagttaaatattcagcaaattgccaataaagtcggatactcctcagaaacagcttttagtcaggcatttaaacgtcaatttgaacaatctcctaaacactatcgccagcaatcatgataataatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_B0012_sequence
1
tcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_B0015_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z