BBa_K206000
1
pBAD
pBAD strong
2009-10-13T11:00:00Z
2015-05-08T01:11:23Z
The sequence was obtained by applying all mutations that upregulated AraC binding and subsequent promoter activity listed in reference [1].
Released HQ 2013
pBAD is an <i>E.coli</i> promoter that is induced by L-arabinose. K206000 is a mutagenized pBAD promoter that is responsive to lower concentrations of arabinose than wild type (<partinfo>I13453</partinfo>) and, additionally, exhibits a higher maximum of protein expression as measured by coupling to a fluorescent reporter.
false
false
_307_
0
4172
9
In stock
true
There were no special design considerations.
false
Amelia Hardjasa
annotation2049252
1
promoter
range2049252
1
1
131
annotation2049253
1
AraI1
range2049253
1
40
57
annotation2049254
1
AraI2
range2049254
1
61
78
BBa_K1055007
1
BBa_K1055007
FsC: functional cutinase
2013-09-17T11:00:00Z
2015-05-08T01:08:57Z
fungus Fusarium solani pisi
The part enables the user to produce functional cutinase from fungus Fusarium solani pisi which is a cuticula degrading hydrolase. The enzyme is fused to mRFP to allow tracking of expression and also provides a His-Tag for subsequent purification. Both, mRFP and His-Tag, can be cleaved using TEV-Protease.
false
false
_1362_
0
16980
9
It's complicated
false
Despite BioBricks the part also consists of the RBS from pET22b(+), a TEV-site and a His-Tag.
false
Sven Jager, Sebastian Wagner and Anne Schieferdecker
component2352865
1
BBa_K808025
component2352868
1
BBa_E1010
component2352862
1
BBa_K206000
component2352864
1
BBa_J32015
annotation2352862
1
BBa_K206000
range2352862
1
1
130
annotation2352864
1
BBa_J32015
range2352864
1
137
202
annotation2352865
1
BBa_K808025
range2352865
1
209
859
annotation2352868
1
BBa_E1010
range2352868
1
866
1571
BBa_K808025
1
BBa_K808025
FsC: Cutinase PET cleaving enzyme
2012-09-01T11:00:00Z
2015-05-08T01:13:26Z
Cloned from vector pEST100 from Becker et all 2005:
(Becker, S., Theile, S., Heppeler, N., Michalczyk, A., Wentzel, A., Wilhelm, S., Jaeger, K.-E., et al. (2005). A generic system for the Escherichia coli cell-surface display of lipolytic enzymes. FEBS letters, 579(5), 1177???82. doi:10.1016/j.febslet.2004.12.087)
Released HQ 2013
A cutinase is a cuticula degrading hydrolase from the fungus Fusarium solani pisi. It shows activity towards PET.
false
false
_1065_
0
11792
9
In stock
false
Surface Expression is very hard to do. FsC shows lipolytic activity and attacks the outer membrane of gramm negativ bacteria. This activity leads to a certain toxicity for expression hosts. In addition FsC needs to be expressed in the periplasm due to folding issues.
false
Marie Burghard, Henrik Cordes, Jascha Diemer, Adrian Eilingsfeld, Sven Jager, Rene Sahm, Arne Wehling
BBa_E1010
1
mRFP1
**highly** engineered mutant of red fluorescent protein from Discosoma striata (coral)
2004-07-27T11:00:00Z
2015-08-31T04:07:26Z
Campbell et al., PNAS v99 p7877 <a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=12060735">URL</a>
Released HQ 2013
monomeric RFP:
Red Fluorescent Protein.
Excitation peak: 584 nm
Emission peak: 607 nm
false
false
_11_1_
0
52
7
In stock
false
TAATAA double stop codon added (DE).
Four silent mutations made to remove three EcoRI sites and one PstI site: A28G, A76G, A349G, G337A.
true
Drew Endy
annotation2214014
1
Help:Barcodes
range2214014
1
682
706
annotation1014044
1
mrfp1
range1014044
1
1
675
BBa_J32015
1
PelB
PelB leader sequence; directs protein to E. coli periplasmic membrane
2006-08-24T11:00:00Z
2015-08-31T04:08:46Z
Novagen
Released HQ 2013
The pelB leader sequence is a sequence of amino acids which when attached to a protein, directs the protein to the periplasmic membrane of E. coli, where the sequence is removed by pelB peptidase. It is used to direct coat protein-antigen fusions to the cell surface.
false
true
_50_
0
495
50
In stock
true
.
true
Austen Heinz
annotation1898182
1
PelB
range1898182
1
1
66
BBa_K1055007_sequence
1
acattgattatttgcacggcgtcacactttgctatgccatagcaagatagtccataagattagcggatcctacctgacgctttttatcgcaactctctactgtttctccataccgtttttttgggctagctactagatgaaatacctgctgccgaccgctgctgctggtctgctgctcctcgctgcccagccggcgatggcctactagatgctgcctacttctaaccctgctcaggagcttgaggcgcgccagcttggtagaacaactcgcgacgatctgatcaacggcaatagcgcttcctgcgccgatgtcatcttcatttatgcccggggttcaacagagacgggcaacttgggaactctcggtcctagcattgcctccaaccttgagtccgccttcggcaaggacggtgtctggattcagggcgttggcggtgcctaccgagccactcttggagacaatgctctccctcgcggtacctctagcgccgcaatcagggagatgcttggtctcttccagcaggccaacaccaagtgccctgacgcgactttgatcgccggtggctacagccagggtgctgcacttgcggccgcctccatcgaggacctcgactcggccattcgtgacaagatcgccggaactgttctgttcggctacaccaagaacctacagaaccgtggccgaatccccaactaccctgccgacaggaccaaggtcttctgcaatacaggagatctcgtttgtactggtagcttgatcgttgctgcacctcacttggcttatggtcctgatgctcggggccctgcccctgagttcctcatcgagaaggttcgggctgtccgtggttctgcttaataatactagatggcttcctccgaagacgttatcaaagagttcatgcgtttcaaagttcgtatggaaggttccgttaacggtcacgagttcgaaatcgaaggtgaaggtgaaggtcgtccgtacgaaggtacccagaccgctaaactgaaagttaccaaaggtggtccgctgccgttcgcttgggacatcctgtccccgcagttccagtacggttccaaagcttacgttaaacacccggctgacatcccggactacctgaaactgtccttcccggaaggtttcaaatgggaacgtgttatgaacttcgaagacggtggtgttgttaccgttacccaggactcctccctgcaagacggtgagttcatctacaaagttaaactgcgtggtaccaacttcccgtccgacggtccggttatgcagaaaaaaaccatgggttgggaagcttccaccgaacgtatgtacccggaagacggtgctctgaaaggtgaaatcaaaatgcgtctgaaactgaaagacggtggtcactacgacgctgaagttaaaaccacctacatggctaaaaaaccggttcagctgccgggtgcttacaaaaccgacatcaaactggacatcacctcccacaacgaagactacaccatcgttgaacagtacgaacgtgctgaaggtcgtcactccaccggtgcttaataacgctgatagtgctagtgtagatcgc
BBa_E1010_sequence
1
atggcttcctccgaagacgttatcaaagagttcatgcgtttcaaagttcgtatggaaggttccgttaacggtcacgagttcgaaatcgaaggtgaaggtgaaggtcgtccgtacgaaggtacccagaccgctaaactgaaagttaccaaaggtggtccgctgccgttcgcttgggacatcctgtccccgcagttccagtacggttccaaagcttacgttaaacacccggctgacatcccggactacctgaaactgtccttcccggaaggtttcaaatgggaacgtgttatgaacttcgaagacggtggtgttgttaccgttacccaggactcctccctgcaagacggtgagttcatctacaaagttaaactgcgtggtaccaacttcccgtccgacggtccggttatgcagaaaaaaaccatgggttgggaagcttccaccgaacgtatgtacccggaagacggtgctctgaaaggtgaaatcaaaatgcgtctgaaactgaaagacggtggtcactacgacgctgaagttaaaaccacctacatggctaaaaaaccggttcagctgccgggtgcttacaaaaccgacatcaaactggacatcacctcccacaacgaagactacaccatcgttgaacagtacgaacgtgctgaaggtcgtcactccaccggtgcttaataacgctgatagtgctagtgtagatcgc
BBa_J32015_sequence
1
atgaaatacctgctgccgaccgctgctgctggtctgctgctcctcgctgcccagccggcgatggcc
BBa_K206000_sequence
1
acattgattatttgcacggcgtcacactttgctatgccatagcaagatagtccataagattagcggatcctacctgacgctttttatcgcaactctctactgtttctccataccgtttttttgggctagc
BBa_K808025_sequence
1
atgctgcctacttctaaccctgctcaggagcttgaggcgcgccagcttggtagaacaactcgcgacgatctgatcaacggcaatagcgcttcctgcgccgatgtcatcttcatttatgcccggggttcaacagagacgggcaacttgggaactctcggtcctagcattgcctccaaccttgagtccgccttcggcaaggacggtgtctggattcagggcgttggcggtgcctaccgagccactcttggagacaatgctctccctcgcggtacctctagcgccgcaatcagggagatgcttggtctcttccagcaggccaacaccaagtgccctgacgcgactttgatcgccggtggctacagccagggtgctgcacttgcggccgcctccatcgaggacctcgactcggccattcgtgacaagatcgccggaactgttctgttcggctacaccaagaacctacagaaccgtggccgaatccccaactaccctgccgacaggaccaaggtcttctgcaatacaggagatctcgtttgtactggtagcttgatcgttgctgcacctcacttggcttatggtcctgatgctcggggccctgcccctgagttcctcatcgagaaggttcgggctgtccgtggttctgcttaataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z