BBa_J23105
1
BBa_J23105
constitutive promoter family member
2006-08-13T11:00:00Z
2015-08-31T04:08:40Z
Isolated from library of promoters
Later
false
true
_52_
0
483
95
In stock
true
N/A
true
John Anderson
BBa_B0010
1
BBa_B0010
T1 from E. coli rrnB
2003-11-19T12:00:00Z
2015-08-31T04:07:20Z
Transcriptional terminator consisting of a 64 bp stem-loop.
false
false
_1_
0
24
7
In stock
false
true
Randy Rettberg
annotation7018
1
BBa_B0010
range7018
1
1
80
annotation4184
1
stem_loop
range4184
1
12
55
BBa_B0032
1
BBa_B0032
RBS.3 (medium) -- derivative of BBa_0030
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
Weak1 RBS based on Ron Weiss thesis. Strength is considered relative to <bb_part>BBa_B0030</bb_part>, <bb_part>BBa_B0031</bb_part>, <bb_part>BBa_B0033</bb_part>.
false
true
_41_44_48_46_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix ("RBS-2" in figure 4-14 of thesis). <P>
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation1709
1
RBS-3\Weak
range1709
1
1
13
annotation7027
1
BBa_B0032
range7027
1
1
13
annotation1710
1
RBS
range1710
1
7
10
BBa_B0012
1
BBa_B0012
TE from coliphageT7
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Derived from the TE terminator of T7 bacteriophage between Genes 1.3 and 1.4 <genbank>V01146</genbank>.
Released HQ 2013
Transcription terminator for the <i>E.coli</i> RNA polymerase.
false
false
_1_
0
24
7
In stock
false
<P> <P>Suggested by Sri Kosuri and Drew Endy as a high efficiency terminator. The 5' end cutoff was placed immediately after the TAA stop codon and the 3' end cutoff was placed just prior to the RBS of Gene 1.4 (before AAGGAG).<P> Use anywhere transcription should be stopped when the gene of interest is upstream of this terminator.
false
Reshma Shetty
annotation7020
1
BBa_B0012
range7020
1
1
41
annotation1690
1
polya
range1690
1
28
41
annotation1687
1
stop
range1687
1
34
34
annotation1686
1
T7 TE
range1686
1
8
27
BBa_K1075018
1
BBa_K1075018
J23105-RBS32-SspB[Core]-LOV-ipaA-TT
2013-09-22T11:00:00Z
2015-05-08T01:09:02Z
a
a
false
false
_1384_
0
16105
9
Not in stock
false
a
false
Marc Schulte
component2368765
1
BBa_J23105
component2368778
1
BBa_K1075017
annotation2368765
1
BBa_J23105
range2368765
1
1
35
annotation2368778
1
BBa_K1075017
range2368778
1
44
1039
BBa_K1075017
1
BBa_K1075017
RBS32-sspB[Core]-LOV-ipaA-TT
2013-09-22T11:00:00Z
2015-05-08T01:09:02Z
a
a
false
false
_1384_
0
16105
9
It's complicated
false
a
false
Marc Schulte
component2368742
1
BBa_B0015
component2368735
1
BBa_K1075012
component2368732
1
BBa_B0032
component2368734
1
BBa_K1075008
annotation2368732
1
BBa_B0032
range2368732
1
1
13
annotation2368734
1
BBa_K1075008
range2368734
1
20
358
annotation2368735
1
BBa_K1075012
range2368735
1
365
859
annotation2368742
1
BBa_B0015
range2368742
1
868
996
BBa_B0015
1
BBa_B0015
double terminator (B0010-B0012)
2003-07-16T11:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
Double terminator consisting of BBa_B0010 and BBa_B0012
false
true
_1_
0
24
7
In stock
false
true
Reshma Shetty
component1916610
1
BBa_B0010
component1916612
1
BBa_B0012
annotation1916612
1
BBa_B0012
range1916612
1
89
129
annotation1916610
1
BBa_B0010
range1916610
1
1
80
BBa_K1075008
1
BBa_K1075008
E. coli sspB[Core]
2013-09-21T11:00:00Z
2015-05-08T01:09:02Z
PCR amplification of full length E. coli sspB. Originally E. Coli sspB is found in the genome of E. coli.
EcsspB itself regulates the degradation of ssrA tagged proteins through the ClpXP protease in procaryotes. In engineered systems it is used to induce degradation of specifically ssrA tagged proteins.
This construct is part of the split system of E. Coli sspB (EcsspB) which was used in fusion with FKBP and FRB to induce the activity of sspB and therefore degradation of proteins with Rapamycins. [1]
EcsspB can be functionally divided in three parts: [2]
-the N terminal Core domain (113 AA)
-the C terminal XB peptide (25 AA)
-and a 'flexible linker' in between the first parts (28 AA)
We used the same domain structure as is used within the Rapamycin inducable split system. [1]
While the Core domain is responsible for dimerization of sspB and binding of ssrA the XB peptide binds the protease ClpXP. The flexible linker is called flexible because it was found, that an increase or reduction in size or amino acid composition does not influence the function of sspB as much as it would in the other domains. [3]
For our project we needed the sspB split system to engineer a light inducable sspB.
false
false
_1384_
0
12108
9
It's complicated
false
We used the same length of the XB peptide than used for the Rapamycin inducable split system. [1]
false
Max Schelski
BBa_K1075012
1
BBa_K1075012
AsLOV2-ipaA
2013-09-22T11:00:00Z
2015-05-08T01:09:02Z
it was amplified from a plasmid from Addgene - provided by Klaus Hahn. LOV2 originally comes from Avena sativa while the ipaA peptide comes from Shigella spp.
Fusion of LOV 2 (A. sativa) with the ipaA peptide. It forms light inducable a tight dimer with Vinculin. [1]
false
false
_1384_
0
12108
9
Not in stock
false
the fusion protein was designed by Lungu et al. [1]
false
Max Schelski
BBa_K1075017_sequence
1
tcacacaggaaagtactagatggatttgtcacagctaacaccacgtcgtccctatctgctgcgtgcattctatgagtggttgctggataaccagctcacgccgcacctggtggtggatgtgacgctccctggcgtgcaggttcctatggaatatgcgcgtgacgggcaaatcgtactcaacattgcgccgcgtgctgtcggcaatctggaactggcgaatgatgaggtgcgctttaacgcgcgctttggtggcattccgcgtcaggtttctgtgccgctggctgccgtgctggctatctacgcccgtgaaaatggcgcaggcacgatgttcgaacctgaagctgcctacgatgaagattactagatgcatcatcatcatcatcatggcagcctggcgaccaccctggaacgtattgaaaagaactttgtgattaccgatccgcgtctgccggataacccgattatttttgcgagcgatagctttctgcaactgaccgaatatagccgtgaagaaattctgggccgtaactgccgttttctgcaaggcccggaaaccgatcgtgcgaccgtgcgtaaaattcgtgatgcgattgataaccagaccgaagtgaccgtgcagctgattaactataccaaaagcggcaaaaaattttggaacctgtttcatctgcaaccgatgcgtgatcagaaaggcgatgtgcagtattttattggcgtgcagaaggatggtaccgaacatgtgcgtgatgcggcggaacgtgaaggcgtgatggaaatcaagaaaaccgcgaacaacattattaaagcggcgaaagatgtgaccaccagcctgagcaaagtgctgaaaaacattaactaatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_B0010_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctc
BBa_K1075018_sequence
1
tttacggctagctcagtcctaggtactatgctagctactagagtcacacaggaaagtactagatggatttgtcacagctaacaccacgtcgtccctatctgctgcgtgcattctatgagtggttgctggataaccagctcacgccgcacctggtggtggatgtgacgctccctggcgtgcaggttcctatggaatatgcgcgtgacgggcaaatcgtactcaacattgcgccgcgtgctgtcggcaatctggaactggcgaatgatgaggtgcgctttaacgcgcgctttggtggcattccgcgtcaggtttctgtgccgctggctgccgtgctggctatctacgcccgtgaaaatggcgcaggcacgatgttcgaacctgaagctgcctacgatgaagattactagatgcatcatcatcatcatcatggcagcctggcgaccaccctggaacgtattgaaaagaactttgtgattaccgatccgcgtctgccggataacccgattatttttgcgagcgatagctttctgcaactgaccgaatatagccgtgaagaaattctgggccgtaactgccgttttctgcaaggcccggaaaccgatcgtgcgaccgtgcgtaaaattcgtgatgcgattgataaccagaccgaagtgaccgtgcagctgattaactataccaaaagcggcaaaaaattttggaacctgtttcatctgcaaccgatgcgtgatcagaaaggcgatgtgcagtattttattggcgtgcagaaggatggtaccgaacatgtgcgtgatgcggcggaacgtgaaggcgtgatggaaatcaagaaaaccgcgaacaacattattaaagcggcgaaagatgtgaccaccagcctgagcaaagtgctgaaaaacattaactaatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_J23105_sequence
1
tttacggctagctcagtcctaggtactatgctagc
BBa_B0032_sequence
1
tcacacaggaaag
BBa_K1075008_sequence
1
atggatttgtcacagctaacaccacgtcgtccctatctgctgcgtgcattctatgagtggttgctggataaccagctcacgccgcacctggtggtggatgtgacgctccctggcgtgcaggttcctatggaatatgcgcgtgacgggcaaatcgtactcaacattgcgccgcgtgctgtcggcaatctggaactggcgaatgatgaggtgcgctttaacgcgcgctttggtggcattccgcgtcaggtttctgtgccgctggctgccgtgctggctatctacgcccgtgaaaatggcgcaggcacgatgttcgaacctgaagctgcctacgatgaagat
BBa_K1075012_sequence
1
atgcatcatcatcatcatcatggcagcctggcgaccaccctggaacgtattgaaaagaactttgtgattaccgatccgcgtctgccggataacccgattatttttgcgagcgatagctttctgcaactgaccgaatatagccgtgaagaaattctgggccgtaactgccgttttctgcaaggcccggaaaccgatcgtgcgaccgtgcgtaaaattcgtgatgcgattgataaccagaccgaagtgaccgtgcagctgattaactataccaaaagcggcaaaaaattttggaacctgtttcatctgcaaccgatgcgtgatcagaaaggcgatgtgcagtattttattggcgtgcagaaggatggtaccgaacatgtgcgtgatgcggcggaacgtgaaggcgtgatggaaatcaagaaaaccgcgaacaacattattaaagcggcgaaagatgtgaccaccagcctgagcaaagtgctgaaaaacattaactaa
BBa_B0012_sequence
1
tcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_B0015_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z