BBa_K1085028
1
BBa_K1085028
RBS Start-codon SpiderSilkSubunitE1 SpiderSilkSubunitE2 x2 SilkTail Strep-tag Stop-codon
2013-09-15T11:00:00Z
2015-05-08T01:09:05Z
blabla
blabla
false
false
_1395_
0
16111
9
It's complicated
false
blabla
false
Claudio Tiecher
component2347040
1
BBa_K1085002
component2347042
1
BBa_K1085002
component2347038
1
BBa_K1085001
component2347045
1
BBa_K1085009
annotation2347040
1
BBa_K1085002
range2347040
1
235
444
annotation2347038
1
BBa_K1085001
range2347038
1
1
226
annotation2347042
1
BBa_K1085002
range2347042
1
453
662
annotation2347045
1
BBa_K1085009
range2347045
1
671
985
BBa_K1085009
1
BBa_K1085009
SilkTail Strep-tag Stop-codon
2013-09-09T11:00:00Z
2015-06-02T12:11:00Z
The amino acid sequence of the tail was obtained from MaSp2. The DNA sequence was synthesized by Integrated DNA Technologies (IDT).
This BioBrick contains the coding sequence for silk tail with a Strep-tag behind it and ends with a stop codon.
The Tail ??????.
The Strep-tag, fused at the C terminal, is used both as a binding tag to use to inidicate its production and as a binding component to biotin.
false
false
_1395_
4206
16089
9
In stock
false
The DNA sequence was codon-optimized for Bacillus Subtilis. Moreover the nucleotide sequence was optimized in order to accomplish the production standard of IDT. A couple of optimized codons were affected by this.
false
Claudio Tiecher
annotation2339061
1
strep
range2339061
1
289
312
annotation2339062
1
spidersilk C-terminal domain
range2339062
1
1
270
annotation2362391
1
Stop codon (TGA)
range2362391
1
313
315
BBa_K1085002
1
BBa_K1085002
SpiderSilkSubunitE2
2013-09-09T11:00:00Z
2016-02-10T01:08:23Z
The amino acids sequence of the silk protein was obtained from the paper by Brooks et al. (2008). The DNA sequence was synthesized by Integrated DNA Technologies (IDT).
This BioBrick contains the coding sequence for part of the spider silk protein (SubunitE1) with Bacillus Subtilis ribosome binding site (RBS) infront of it.
The RBS is there to allow the ribosomes to bind and start to translate the DNA.
SubunitE1 codes for a spider silk protein that is optimized for maximal expression in Bacillus subtillus 168. The primary goal of the algorithm was to optimize the codon selection based on their availbility scores. The secondary goal was to prevent the formation of secondary RNA structures in close proximity to the RBS, and the tetrary goal was to minimize the number of restriction sites.
The amino acid sequence is based on the adapted MaSp2 sequences discribed in the paper of Brooks et. al. 2008.
false
false
_1395_
0
4206
16089
9
In stock
false
The DNA sequence was codon-optimized for Bacillus Subtilis. Moreover the nucleotide sequence was optimized in order to accomplish the production standard of IDT. A couple of optimized codons were affected by this.
false
Claudio Tiecher
annotation2339043
1
spidersilk subunit E2
range2339043
1
1
210
BBa_K1085001
1
BBa_K1085001
RBS Start-codon SpiderSilkSubunitE1
2013-09-09T11:00:00Z
2016-02-10T01:07:59Z
The amino acids sequence of the silk protein was obtained from the paper by Brooks et al. (2008). The DNA sequence was synthesized by Integrated DNA Technologies (IDT).
This BioBrick contains the coding sequence for part of the spider silk protein (SubunitE1) with Bacillus Subtilis ribosome binding site (RBS) infront of it.
The RBS is there to allow the ribosomes to bind and start to translate the DNA.
SubunitE1 codes for a spider silk protein that is optimized to prevent the forming of secundary RNA structures in close proximity to the RBS. This is given priority over reducing the number of restriction sites. However, the primary goal of the algorithm was still to optimize the codon selection based on their availbility scores.
false
false
_1395_
4206
16089
9
In stock
false
The DNA sequence was codon-optimized for Bacillus Subtilis. Moreover the nucleotide sequence was optimized in order to accomplish the production standard of IDT. A couple of optimized codons were affected by this.
false
Claudio Tiecher
annotation2338312
1
spidersilk subunit E1
range2338312
1
17
226
annotation2338309
1
RBS
range2338309
1
1
6
annotation2338314
1
starting codon (ATG)
range2338314
1
14
16
BBa_K1085002_sequence
1
ggcggatacggcccaggcgcaggccaacaaggaccaggcagccaaggaccaggctcaggcggacaacaaggcccaggcggacaaggcggctacggcccaggcgccggacaacaaggaccaggctcacaaggaccaggctccggcggacaacaaggaccaggcggccaaggaccatacggaccaagcgcagcagccgcagcagccgccgca
BBa_K1085028_sequence
1
aggaggcatatccatgggcggatacggaccaggagcaggccaacaaggcccaggctcacaaggcccaggctcaggcggacaacaaggaccaggcggacaaggcggctacggaccaggcgccggacaacaaggcccaggcagccaaggaccaggcagcggcggccaacaaggcccaggaggacaaggaccatacggcccaagcgcagcagccgcagcagccgcagcctactagagggcggatacggcccaggcgcaggccaacaaggaccaggcagccaaggaccaggctcaggcggacaacaaggcccaggcggacaaggcggctacggcccaggcgccggacaacaaggaccaggctcacaaggaccaggctccggcggacaacaaggaccaggcggccaaggaccatacggaccaagcgcagcagccgcagcagccgccgcatactagagggcggatacggcccaggcgcaggccaacaaggaccaggcagccaaggaccaggctcaggcggacaacaaggcccaggcggacaaggcggctacggcccaggcgccggacaacaaggaccaggctcacaaggaccaggctccggcggacaacaaggaccaggcggccaaggaccatacggaccaagcgcagcagccgcagcagccgccgcatactagaggccccagttgcctccgcagccgcctcaaggctgtcctcccctcaagcctcctcccgtgtttcatccgccgtgtccactctcgtgtcctccggacctacgaatcctgccgccttatccaatgccatctccagcgttgtatcacaagtttcagcctccaatcctggactatccggatgtgacgttctcgttcaagccctcctcgaactcgtatccgccctcgtacacatcctcggctcctcctccattggacaaattaattacgccgcctcctccgcagcagcatccgcatggagccatccgcagtttgaaaaatga
BBa_K1085009_sequence
1
gccccagttgcctccgcagccgcctcaaggctgtcctcccctcaagcctcctcccgtgtttcatccgccgtgtccactctcgtgtcctccggacctacgaatcctgccgccttatccaatgccatctccagcgttgtatcacaagtttcagcctccaatcctggactatccggatgtgacgttctcgttcaagccctcctcgaactcgtatccgccctcgtacacatcctcggctcctcctccattggacaaattaattacgccgcctcctccgcagcagcatccgcatggagccatccgcagtttgaaaaatga
BBa_K1085001_sequence
1
aggaggcatatccatgggcggatacggaccaggagcaggccaacaaggcccaggctcacaaggcccaggctcaggcggacaacaaggaccaggcggacaaggcggctacggaccaggcgccggacaacaaggcccaggcagccaaggaccaggcagcggcggccaacaaggcccaggaggacaaggaccatacggcccaagcgcagcagccgcagcagccgcagcc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z