BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_I0500
1
pBad/araC
Inducible pBad/araC promoter
2003-12-05T12:00:00Z
2015-08-31T04:07:29Z
-- No description --
false
true
_1_
0
24
7
In stock
false
true
Sri Kosuri
annotation1498842
1
PC
range1498842
1
1043
1114
annotation1498843
1
AraC
range1498843
1
1
1079
annotation1498841
1
Pbad
range1498841
1
1080
1210
BBa_K1113701
1
BBa_K1113701
Targeting sequence for the delivery to the Carboxysome
2013-09-17T11:00:00Z
2015-05-08T01:09:11Z
The large subunits of the RuBisCo was obtained from the pHnCBS1D plasmid (plasmid provided by David Savage, Departments of Molecular & Cell Biology and Chemistry, University of California, Berkeley)
This targeting sequence consist in the large subunit of the ribulose-1,5-bisphosphate carboxylase/oxygenase enzyme and it???s constructed to deliver proteins of interest to the Carboxysome
false
false
_1424_
0
17949
9
Not in stock
false
-
false
Belen Cespedes
BBa_I746916
1
BBa_I746916
superfolder GFP coding sequence
2008-09-29T11:00:00Z
2015-08-31T04:08:05Z
Superfolder GFP was originally described by: Pedelacq et al (2006): "Engineering and characterization of a superfolder green fluorescent protein", Nature Biotech 24 (1) January 2006
This version was synthesised de novo (by Geneart).
This is the coding sequence of superfolder GFP (Pedelacq et al (2006): "Engineering and characterization of a superfolder green fluorescent protein", Nature Biotech 24 (1) January 2006).
It carries the following amino acid changes with respect to mut3 GFP (E0040), the currently most commonly used GFP in the registry:
S30R, Y39N, F64L, G65T, F99S, N105T, Y145F, M153T, V163A, I171V, A206V
Its in-vivo properties are considerably improved with respect to mut3 - it develops fluorescence about 3fold faster than mut3 GFP and reaches 4fold higher absolute fluorescence levels. Fluorescenct colonies can be identified with the naked eye even without UV or blue light illumination (that is to say the amount of blue light in normal daylight or lablight is sufficient).
Additionally it is more stable in vitro and refolds faster after in vitro denaturation with respect to mut3 GFP.
Note:
Superfolder GFP is available in constructs driven by the pBAD and T7 promoters: part numbers I746908 and I746909 respectively. Additionally 6-his tagged versions for protein purification exist: I746914 (pBAD driven) and I746915 (T7 driven).
false
false
_116_
0
2122
9
It's complicated
false
Codon optimisation before de novo synthesis was carried out for both, E.coli and Bacillus subtilis.
false
Stefan Milde
annotation1977533
1
start
range1977533
1
1
3
annotation1977535
1
stop
range1977535
1
715
720
annotation1977534
1
superfolder GFP coding region
range1977534
1
1
720
BBa_K1113002
1
BBa_K1113002
Targeting sequence for the delivery of GFP to the Carboxysome
2013-09-17T11:00:00Z
2015-05-08T01:09:11Z
The large subunits of the RuBisCo was obtained from the pHnCBS1D plasmid (plasmid provided by David Savage, Departments of Molecular & Cell Biology and Chemistry, University of California, Berkeley)
This targeting sequence consist in the large subunit of the ribulose-1,5-bisphosphate carboxylase/oxygenase enzyme (BBa_K1113701) attached with a flexible linker (BBa_K105012) to the superfolder GFP (BBa_I746916) under the regulation of the pBad/araC promoter (BBa_I0500) and includes a RBS (BBa_B0034). The targeting sequence it???s constructed to deliver the fluorescent to the carboxysome under the induction with arabinose
false
false
_1424_
0
17949
9
It's complicated
false
This part it constructed with a mutation in the Prefix (from ???cggccgc??? to ???atacctg???) which erase the NotI restriction site, this modification allow the correct design of primers for Gibson assembly. This part its also constructed on the pSB4K5 standard vector
false
Belen Cespedes
component2353337
1
BBa_B0034
component2353338
1
BBa_K1113701
component2353343
1
BBa_I746916
component2353335
1
BBa_I0500
component2353339
1
BBa_K105012
annotation2353337
1
BBa_B0034
range2353337
1
1219
1230
annotation2353339
1
BBa_K105012
range2353339
1
2664
2693
annotation2353338
1
BBa_K1113701
range2353338
1
1237
2655
annotation2353335
1
BBa_I0500
range2353335
1
1
1210
annotation2353343
1
BBa_I746916
range2353343
1
2700
3419
BBa_K105012
1
BBa_K105012
10 aa flexible protein domain linker
2008-10-18T11:00:00Z
2015-05-08T01:08:52Z
Oligos with a yeast optimized coding for the peptide GENLYFQSGG have been ordered
<br\n>
The amino acide sequence corresponds to the interdomaine linker of xxx.
''paper''
This is a 10 amino acides long linker peptide which can be used to join protein domains together in a flexible way. So fusion proteins with variable DNA-binding and activation or repression domains might be assembled.
<br\n>
false
true
_253_
0
3313
9
In stock
true
To enable the fusion with other domains in frame the vector of this BioBrick has no base pair in between the restriction side and the BioBrick. Furthermore, this coding sequence does not include a start codon.<br\n>
For more information about this issus, see:<br\n>
Phillips, I.E. and Silver, P.A. "A new Biobrick Assembly Strategy Designed for Facile Protein Engineering." <br\n>
DSpace http://hdl.handle.net/1721.1/32535 (2006).
true
Manuel Gersbacher, Katja Karstens
BBa_K1113701_sequence
1
atggcagttaaaaagtatagtgctggtgtaaaagaataccggcagacctattggatgccggaatacacaccgttggattccgacatccttgcatgcttcaaaatcaccccacaaccgggtgttgatcgcgaagaagccgcagccgcggttgcagcagaatcttcaaccggcacatggaccaccgtgtggaccgatttgctgaccgacatggactactacaaaggccgtgcctatcgcattgaagacgtacccggtgacgatgcggcattctatgcctttatcgcctacccaatcgacctgttcgaagaagggtcagttgttaacgtgtttacctcactggttggtaacgtgttcggcttcaaagcggtacgcggcctgcgtctggaagatgttcgcttcccactcgcctacgttaaaacctgtggcggcccaccgcacggtattcaagtcgaacgcgacaagatgaacaaatatggtcgcccactgttgggttgcaccatcaagccaaaacttggtttgtctgcgaaaaactacggccgtgccgtatacgagtgcctccgtggcggcctcgacttcactaaagatgatgaaaacatcaattctcagccgttcatgcgctggcgcgatcgcttcttgttcgtacaagacgcgaccgaaactgctgaagcccaaaccggcgaacgcaaaggccattacctcaacgtaacggcgccaactcctgaagaaatgtacaagcgcgcagagtttgccaaagaaattggcgcgccaatcattatgcacgactacatcaccggtggcttcacggccaacactggcttggccaagtggtgtcaagacaacggcgtactgctgcacatccaccgtgcgatgcatgcggttatcgaccgtaacccgaaccacggtattcacttccgtgttctgaccaagattctgcgtttgtcgggtggcgatcacctgcacaccggtaccgttgtcggcaaactggaaggcgaccgtgcctctactctgggctggattgatttgctccgcgaatcgtttatccctgaagatcgctcgcgcggtatcttcttcgatcaagactggggttcaatgccaggcgtattcgctgtggcctctggtggtattcacgtatggcacatgcctgcgctggttaacatctttggtgacgactctgtcctccaattcggtggcggtacgctgggtcatccatggggcaacgctgccggtgctgctgccaaccgtgttgctctggaagcctgcgtagaagcgcgtaaccaaggccgcgatatcgaaaaagaaggcaaagaaattctgactgctgctgcacagcacagcccagaactgaagattgccatggaaacttggaaagagatcaaattcgaatttgacactgtcgacaaactcgacactcaaaatcgt
BBa_K1113002_sequence
1
ttatgacaacttgacggctacatcattcactttttcttcacaaccggcacggaactcgctcgggctggccccggtgcattttttaaatacccgcgagaaatagagttgatcgtcaaaaccaacattgcgaccgacggtggcgataggcatccgggtggtgctcaaaagcagcttcgcctggctgatacgttggtcctcgcgccagcttaagacgctaatccctaactgctggcggaaaagatgtgacagacgcgacggcgacaagcaaacatgctgtgcgacgctggcgatatcaaaattgctgtctgccaggtgatcgctgatgtactgacaagcctcgcgtacccgattatccatcggtggatggagcgactcgttaatcgcttccatgcgccgcagtaacaattgctcaagcagatttatcgccagcagctccgaatagcgcccttccccttgcccggcgttaatgatttgcccaaacaggtcgctgaaatgcggctggtgcgcttcatccgggcgaaagaaccccgtattggcaaatattgacggccagttaagccattcatgccagtaggcgcgcggacgaaagtaaacccactggtgataccattcgcgagcctccggatgacgaccgtagtgatgaatctctcctggcgggaacagcaaaatatcacccggtcggcaaacaaattctcgtccctgatttttcaccaccccctgaccgcgaatggtgagattgagaatataacctttcattcccagcggtcggtcgataaaaaaatcgagataaccgttggcctcaatcggcgttaaacccgccaccagatgggcattaaacgagtatcccggcagcaggggatcattttgcgcttcagccatacttttcatactcccgccattcagagaagaaaccaattgtccatattgcatcagacattgccgtcactgcgtcttttactggctcttctcgctaaccaaaccggtaaccccgcttattaaaagcattctgtaacaaagcgggaccaaagccatgacaaaaacgcgtaacaaaagtgtctataatcacggcagaaaagtccacattgattatttgcacggcgtcacactttgctatgccatagcatttttatccataagattagcggatcctacctgacgctttttatcgcaactctctactgtttctccatacccgtttttttgggctagctactagagaaagaggagaaatactagatggcagttaaaaagtatagtgctggtgtaaaagaataccggcagacctattggatgccggaatacacaccgttggattccgacatccttgcatgcttcaaaatcaccccacaaccgggtgttgatcgcgaagaagccgcagccgcggttgcagcagaatcttcaaccggcacatggaccaccgtgtggaccgatttgctgaccgacatggactactacaaaggccgtgcctatcgcattgaagacgtacccggtgacgatgcggcattctatgcctttatcgcctacccaatcgacctgttcgaagaagggtcagttgttaacgtgtttacctcactggttggtaacgtgttcggcttcaaagcggtacgcggcctgcgtctggaagatgttcgcttcccactcgcctacgttaaaacctgtggcggcccaccgcacggtattcaagtcgaacgcgacaagatgaacaaatatggtcgcccactgttgggttgcaccatcaagccaaaacttggtttgtctgcgaaaaactacggccgtgccgtatacgagtgcctccgtggcggcctcgacttcactaaagatgatgaaaacatcaattctcagccgttcatgcgctggcgcgatcgcttcttgttcgtacaagacgcgaccgaaactgctgaagcccaaaccggcgaacgcaaaggccattacctcaacgtaacggcgccaactcctgaagaaatgtacaagcgcgcagagtttgccaaagaaattggcgcgccaatcattatgcacgactacatcaccggtggcttcacggccaacactggcttggccaagtggtgtcaagacaacggcgtactgctgcacatccaccgtgcgatgcatgcggttatcgaccgtaacccgaaccacggtattcacttccgtgttctgaccaagattctgcgtttgtcgggtggcgatcacctgcacaccggtaccgttgtcggcaaactggaaggcgaccgtgcctctactctgggctggattgatttgctccgcgaatcgtttatccctgaagatcgctcgcgcggtatcttcttcgatcaagactggggttcaatgccaggcgtattcgctgtggcctctggtggtattcacgtatggcacatgcctgcgctggttaacatctttggtgacgactctgtcctccaattcggtggcggtacgctgggtcatccatggggcaacgctgccggtgctgctgccaaccgtgttgctctggaagcctgcgtagaagcgcgtaaccaaggccgcgatatcgaaaaagaaggcaaagaaattctgactgctgctgcacagcacagcccagaactgaagattgccatggaaacttggaaagagatcaaattcgaatttgacactgtcgacaaactcgacactcaaaatcgttactagagggtgaaaatttgtattttcaatctggtggttactagatgcgtaaaggcgaagagctgttcactggtgtcgtccctattctggtggaactggatggtgatgtcaacggtcataagttttccgtgcgtggcgagggtgaaggtgacgcaactaatggtaaactgacgctgaagttcatctgtactactggtaaactgccggtaccttggccgactctggtaacgacgctgacttatggtgttcagtgctttgctcgttatccggaccatatgaagcagcatgacttcttcaagtccgccatgccggaaggctatgtgcaggaacgcacgatttcctttaaggatgacggcacgtacaaaacgcgtgcggaagtgaaatttgaaggcgataccctggtaaaccgcattgagctgaaaggcattgactttaaagaagacggcaatatcctgggccataagctggaatacaattttaacagccacaatgtttacatcaccgccgataaacaaaaaaatggcattaaagcgaattttaaaattcgccacaacgtggaggatggcagcgtgcagctggctgatcactaccagcaaaacactccaatcggtgatggtcctgttctgctgccagacaatcactatctgagcacgcaaagcgttctgtctaaagatccgaacgagaaacgcgatcatatggttctgctggagttcgtaaccgcagcgggcatcacgcatggtatggatgaactgtacaaatgatga
BBa_B0034_sequence
1
aaagaggagaaa
BBa_I746916_sequence
1
atgcgtaaaggcgaagagctgttcactggtgtcgtccctattctggtggaactggatggtgatgtcaacggtcataagttttccgtgcgtggcgagggtgaaggtgacgcaactaatggtaaactgacgctgaagttcatctgtactactggtaaactgccggtaccttggccgactctggtaacgacgctgacttatggtgttcagtgctttgctcgttatccggaccatatgaagcagcatgacttcttcaagtccgccatgccggaaggctatgtgcaggaacgcacgatttcctttaaggatgacggcacgtacaaaacgcgtgcggaagtgaaatttgaaggcgataccctggtaaaccgcattgagctgaaaggcattgactttaaagaagacggcaatatcctgggccataagctggaatacaattttaacagccacaatgtttacatcaccgccgataaacaaaaaaatggcattaaagcgaattttaaaattcgccacaacgtggaggatggcagcgtgcagctggctgatcactaccagcaaaacactccaatcggtgatggtcctgttctgctgccagacaatcactatctgagcacgcaaagcgttctgtctaaagatccgaacgagaaacgcgatcatatggttctgctggagttcgtaaccgcagcgggcatcacgcatggtatggatgaactgtacaaatgatga
BBa_I0500_sequence
1
ttatgacaacttgacggctacatcattcactttttcttcacaaccggcacggaactcgctcgggctggccccggtgcattttttaaatacccgcgagaaatagagttgatcgtcaaaaccaacattgcgaccgacggtggcgataggcatccgggtggtgctcaaaagcagcttcgcctggctgatacgttggtcctcgcgccagcttaagacgctaatccctaactgctggcggaaaagatgtgacagacgcgacggcgacaagcaaacatgctgtgcgacgctggcgatatcaaaattgctgtctgccaggtgatcgctgatgtactgacaagcctcgcgtacccgattatccatcggtggatggagcgactcgttaatcgcttccatgcgccgcagtaacaattgctcaagcagatttatcgccagcagctccgaatagcgcccttccccttgcccggcgttaatgatttgcccaaacaggtcgctgaaatgcggctggtgcgcttcatccgggcgaaagaaccccgtattggcaaatattgacggccagttaagccattcatgccagtaggcgcgcggacgaaagtaaacccactggtgataccattcgcgagcctccggatgacgaccgtagtgatgaatctctcctggcgggaacagcaaaatatcacccggtcggcaaacaaattctcgtccctgatttttcaccaccccctgaccgcgaatggtgagattgagaatataacctttcattcccagcggtcggtcgataaaaaaatcgagataaccgttggcctcaatcggcgttaaacccgccaccagatgggcattaaacgagtatcccggcagcaggggatcattttgcgcttcagccatacttttcatactcccgccattcagagaagaaaccaattgtccatattgcatcagacattgccgtcactgcgtcttttactggctcttctcgctaaccaaaccggtaaccccgcttattaaaagcattctgtaacaaagcgggaccaaagccatgacaaaaacgcgtaacaaaagtgtctataatcacggcagaaaagtccacattgattatttgcacggcgtcacactttgctatgccatagcatttttatccataagattagcggatcctacctgacgctttttatcgcaactctctactgtttctccatacccgtttttttgggctagc
BBa_K105012_sequence
1
ggtgaaaatttgtattttcaatctggtggt
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z