BBa_K1113401
1
BBa_K1113401
Targeting sequence for the delivery of the LacZ gene to the Carboxysome
2013-09-17T11:00:00Z
2015-05-08T01:09:11Z
The large subunits of the RuBisCo was obtained from the pHnCBS1D plasmid (plasmid provided by David Savage, Departments of Molecular & Cell Biology and Chemistry, University of California, Berkeley)
Includes the lacZ gene (BBa_I732005) which encodes for the β-galactosidase attached with a linker (BBa_K105012) to the large subunit of the RuBisCo (BBa_K1113701) under the regulation of the pBad/araC promoter (BBa_I0500) and includes a RBS (BBa_B0034). The construct is for the delivery of the β-galactosidase and test reactions within the carboxysome.
Source of this part: The large subunits of the RuBisCo was obtained from the pHnCBS1D plasmid (plasmid provided by David Savage, Departments of Molecular & Cell Biology and Chemistry, University of California, Berkeley)
false
false
_1424_
0
17949
9
It's complicated
false
This part it constructed with a mutation in the Prefix (from ???cggccgc??? to ???atacctg???) which erase the NotI restriction site, this modification allow the correct design of primers for Gibson assembly
false
Belen Cespedes
component2353321
1
BBa_I0500
component2353323
1
BBa_B0034
component2353324
1
BBa_K1113701
component2353330
1
BBa_I732005
component2353325
1
BBa_K105012
annotation2353325
1
BBa_K105012
range2353325
1
2664
2693
annotation2353321
1
BBa_I0500
range2353321
1
1
1210
annotation2353324
1
BBa_K1113701
range2353324
1
1237
2655
annotation2353323
1
BBa_B0034
range2353323
1
1219
1230
annotation2353330
1
BBa_I732005
range2353330
1
2700
5774
BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_I0500
1
pBad/araC
Inducible pBad/araC promoter
2003-12-05T12:00:00Z
2015-08-31T04:07:29Z
-- No description --
false
true
_1_
0
24
7
In stock
false
true
Sri Kosuri
annotation1498843
1
AraC
range1498843
1
1
1079
annotation1498841
1
Pbad
range1498841
1
1080
1210
annotation1498842
1
PC
range1498842
1
1043
1114
BBa_K1113701
1
BBa_K1113701
Targeting sequence for the delivery to the Carboxysome
2013-09-17T11:00:00Z
2015-05-08T01:09:11Z
The large subunits of the RuBisCo was obtained from the pHnCBS1D plasmid (plasmid provided by David Savage, Departments of Molecular & Cell Biology and Chemistry, University of California, Berkeley)
This targeting sequence consist in the large subunit of the ribulose-1,5-bisphosphate carboxylase/oxygenase enzyme and it???s constructed to deliver proteins of interest to the Carboxysome
false
false
_1424_
0
17949
9
Not in stock
false
-
false
Belen Cespedes
BBa_K105012
1
BBa_K105012
10 aa flexible protein domain linker
2008-10-18T11:00:00Z
2015-05-08T01:08:52Z
Oligos with a yeast optimized coding for the peptide GENLYFQSGG have been ordered
<br\n>
The amino acide sequence corresponds to the interdomaine linker of xxx.
''paper''
This is a 10 amino acides long linker peptide which can be used to join protein domains together in a flexible way. So fusion proteins with variable DNA-binding and activation or repression domains might be assembled.
<br\n>
false
true
_253_
0
3313
9
In stock
true
To enable the fusion with other domains in frame the vector of this BioBrick has no base pair in between the restriction side and the BioBrick. Furthermore, this coding sequence does not include a start codon.<br\n>
For more information about this issus, see:<br\n>
Phillips, I.E. and Silver, P.A. "A new Biobrick Assembly Strategy Designed for Facile Protein Engineering." <br\n>
DSpace http://hdl.handle.net/1721.1/32535 (2006).
true
Manuel Gersbacher, Katja Karstens
BBa_I732005
1
LacZ
lacZ (encoding beta-galactosidase, full-length)
2007-07-05T11:00:00Z
2015-08-31T04:07:56Z
PCR amplified and standardized from BL21
LacZ encodes beta-galactosidase, an intracellular enzyme that cleaves the disaccharide lactose into glucose and galactose. Beta-galactosidase can also cleaves X-gal and ONPG into colorful products.
false
false
_156_
0
1557
9
It's complicated
false
None
true
Zhan Jian
annotation1936872
1
STOP
range1936872
1
3073
3075
annotation1936869
1
C->T
range1936869
1
3024
3024
annotation1936871
1
START
range1936871
1
1
3
annotation1936870
1
lacZ
range1936870
1
1
3075
BBa_K1113701_sequence
1
atggcagttaaaaagtatagtgctggtgtaaaagaataccggcagacctattggatgccggaatacacaccgttggattccgacatccttgcatgcttcaaaatcaccccacaaccgggtgttgatcgcgaagaagccgcagccgcggttgcagcagaatcttcaaccggcacatggaccaccgtgtggaccgatttgctgaccgacatggactactacaaaggccgtgcctatcgcattgaagacgtacccggtgacgatgcggcattctatgcctttatcgcctacccaatcgacctgttcgaagaagggtcagttgttaacgtgtttacctcactggttggtaacgtgttcggcttcaaagcggtacgcggcctgcgtctggaagatgttcgcttcccactcgcctacgttaaaacctgtggcggcccaccgcacggtattcaagtcgaacgcgacaagatgaacaaatatggtcgcccactgttgggttgcaccatcaagccaaaacttggtttgtctgcgaaaaactacggccgtgccgtatacgagtgcctccgtggcggcctcgacttcactaaagatgatgaaaacatcaattctcagccgttcatgcgctggcgcgatcgcttcttgttcgtacaagacgcgaccgaaactgctgaagcccaaaccggcgaacgcaaaggccattacctcaacgtaacggcgccaactcctgaagaaatgtacaagcgcgcagagtttgccaaagaaattggcgcgccaatcattatgcacgactacatcaccggtggcttcacggccaacactggcttggccaagtggtgtcaagacaacggcgtactgctgcacatccaccgtgcgatgcatgcggttatcgaccgtaacccgaaccacggtattcacttccgtgttctgaccaagattctgcgtttgtcgggtggcgatcacctgcacaccggtaccgttgtcggcaaactggaaggcgaccgtgcctctactctgggctggattgatttgctccgcgaatcgtttatccctgaagatcgctcgcgcggtatcttcttcgatcaagactggggttcaatgccaggcgtattcgctgtggcctctggtggtattcacgtatggcacatgcctgcgctggttaacatctttggtgacgactctgtcctccaattcggtggcggtacgctgggtcatccatggggcaacgctgccggtgctgctgccaaccgtgttgctctggaagcctgcgtagaagcgcgtaaccaaggccgcgatatcgaaaaagaaggcaaagaaattctgactgctgctgcacagcacagcccagaactgaagattgccatggaaacttggaaagagatcaaattcgaatttgacactgtcgacaaactcgacactcaaaatcgt
BBa_B0034_sequence
1
aaagaggagaaa
BBa_I0500_sequence
1
ttatgacaacttgacggctacatcattcactttttcttcacaaccggcacggaactcgctcgggctggccccggtgcattttttaaatacccgcgagaaatagagttgatcgtcaaaaccaacattgcgaccgacggtggcgataggcatccgggtggtgctcaaaagcagcttcgcctggctgatacgttggtcctcgcgccagcttaagacgctaatccctaactgctggcggaaaagatgtgacagacgcgacggcgacaagcaaacatgctgtgcgacgctggcgatatcaaaattgctgtctgccaggtgatcgctgatgtactgacaagcctcgcgtacccgattatccatcggtggatggagcgactcgttaatcgcttccatgcgccgcagtaacaattgctcaagcagatttatcgccagcagctccgaatagcgcccttccccttgcccggcgttaatgatttgcccaaacaggtcgctgaaatgcggctggtgcgcttcatccgggcgaaagaaccccgtattggcaaatattgacggccagttaagccattcatgccagtaggcgcgcggacgaaagtaaacccactggtgataccattcgcgagcctccggatgacgaccgtagtgatgaatctctcctggcgggaacagcaaaatatcacccggtcggcaaacaaattctcgtccctgatttttcaccaccccctgaccgcgaatggtgagattgagaatataacctttcattcccagcggtcggtcgataaaaaaatcgagataaccgttggcctcaatcggcgttaaacccgccaccagatgggcattaaacgagtatcccggcagcaggggatcattttgcgcttcagccatacttttcatactcccgccattcagagaagaaaccaattgtccatattgcatcagacattgccgtcactgcgtcttttactggctcttctcgctaaccaaaccggtaaccccgcttattaaaagcattctgtaacaaagcgggaccaaagccatgacaaaaacgcgtaacaaaagtgtctataatcacggcagaaaagtccacattgattatttgcacggcgtcacactttgctatgccatagcatttttatccataagattagcggatcctacctgacgctttttatcgcaactctctactgtttctccatacccgtttttttgggctagc
BBa_K1113401_sequence
1
ttatgacaacttgacggctacatcattcactttttcttcacaaccggcacggaactcgctcgggctggccccggtgcattttttaaatacccgcgagaaatagagttgatcgtcaaaaccaacattgcgaccgacggtggcgataggcatccgggtggtgctcaaaagcagcttcgcctggctgatacgttggtcctcgcgccagcttaagacgctaatccctaactgctggcggaaaagatgtgacagacgcgacggcgacaagcaaacatgctgtgcgacgctggcgatatcaaaattgctgtctgccaggtgatcgctgatgtactgacaagcctcgcgtacccgattatccatcggtggatggagcgactcgttaatcgcttccatgcgccgcagtaacaattgctcaagcagatttatcgccagcagctccgaatagcgcccttccccttgcccggcgttaatgatttgcccaaacaggtcgctgaaatgcggctggtgcgcttcatccgggcgaaagaaccccgtattggcaaatattgacggccagttaagccattcatgccagtaggcgcgcggacgaaagtaaacccactggtgataccattcgcgagcctccggatgacgaccgtagtgatgaatctctcctggcgggaacagcaaaatatcacccggtcggcaaacaaattctcgtccctgatttttcaccaccccctgaccgcgaatggtgagattgagaatataacctttcattcccagcggtcggtcgataaaaaaatcgagataaccgttggcctcaatcggcgttaaacccgccaccagatgggcattaaacgagtatcccggcagcaggggatcattttgcgcttcagccatacttttcatactcccgccattcagagaagaaaccaattgtccatattgcatcagacattgccgtcactgcgtcttttactggctcttctcgctaaccaaaccggtaaccccgcttattaaaagcattctgtaacaaagcgggaccaaagccatgacaaaaacgcgtaacaaaagtgtctataatcacggcagaaaagtccacattgattatttgcacggcgtcacactttgctatgccatagcatttttatccataagattagcggatcctacctgacgctttttatcgcaactctctactgtttctccatacccgtttttttgggctagctactagagaaagaggagaaatactagatggcagttaaaaagtatagtgctggtgtaaaagaataccggcagacctattggatgccggaatacacaccgttggattccgacatccttgcatgcttcaaaatcaccccacaaccgggtgttgatcgcgaagaagccgcagccgcggttgcagcagaatcttcaaccggcacatggaccaccgtgtggaccgatttgctgaccgacatggactactacaaaggccgtgcctatcgcattgaagacgtacccggtgacgatgcggcattctatgcctttatcgcctacccaatcgacctgttcgaagaagggtcagttgttaacgtgtttacctcactggttggtaacgtgttcggcttcaaagcggtacgcggcctgcgtctggaagatgttcgcttcccactcgcctacgttaaaacctgtggcggcccaccgcacggtattcaagtcgaacgcgacaagatgaacaaatatggtcgcccactgttgggttgcaccatcaagccaaaacttggtttgtctgcgaaaaactacggccgtgccgtatacgagtgcctccgtggcggcctcgacttcactaaagatgatgaaaacatcaattctcagccgttcatgcgctggcgcgatcgcttcttgttcgtacaagacgcgaccgaaactgctgaagcccaaaccggcgaacgcaaaggccattacctcaacgtaacggcgccaactcctgaagaaatgtacaagcgcgcagagtttgccaaagaaattggcgcgccaatcattatgcacgactacatcaccggtggcttcacggccaacactggcttggccaagtggtgtcaagacaacggcgtactgctgcacatccaccgtgcgatgcatgcggttatcgaccgtaacccgaaccacggtattcacttccgtgttctgaccaagattctgcgtttgtcgggtggcgatcacctgcacaccggtaccgttgtcggcaaactggaaggcgaccgtgcctctactctgggctggattgatttgctccgcgaatcgtttatccctgaagatcgctcgcgcggtatcttcttcgatcaagactggggttcaatgccaggcgtattcgctgtggcctctggtggtattcacgtatggcacatgcctgcgctggttaacatctttggtgacgactctgtcctccaattcggtggcggtacgctgggtcatccatggggcaacgctgccggtgctgctgccaaccgtgttgctctggaagcctgcgtagaagcgcgtaaccaaggccgcgatatcgaaaaagaaggcaaagaaattctgactgctgctgcacagcacagcccagaactgaagattgccatggaaacttggaaagagatcaaattcgaatttgacactgtcgacaaactcgacactcaaaatcgttactagagggtgaaaatttgtattttcaatctggtggttactagatgaccatgattacggattcactggccgtcgttttacaacgtcgtgactgggaaaaccctggcgttacccaacttaatcgccttgcagcacatccccctttcgccagctggcgtaatagcgaagaggcccgcaccgatcgcccttcccaacagttgcgcagcctgaatggcgaatggcgctttgcctggtttccggcaccagaagcggtgccggaaagctggctggagtgcgatcttcctgaggccgatactgtcgtcgtcccctcaaactggcagatgcacggttacgatgcgcccatctacaccaacgtgacctatcccattacggtcaatccgccgtttgttcccacggagaatccgacgggttgttactcgctcacatttaatgttgatgaaagctggctacaggaaggccagacgcgaattatttttgatggcgttaactcggcgtttcatctgtggtgcaacgggcgctgggtcggttacggccaggacagtcgtttgccgtctgaatttgacctgagcgcatttttacgcgccggagaaaaccgcctcgcggtgatggtgctgcgctggagtgacggcagttatctggaagatcaggatatgtggcggatgagcggcattttccgtgacgtctcgttgctgcataaaccgactacacaaatcagcgatttccatgttgccactcgctttaatgatgatttcagccgcgctgtactggaggctgaagttcagatgtgcggcgagttgcgtgactacctacgggtaacagtttctttatggcagggtgaaacgcaggtcgccagcggcaccgcgcctttcggcggtgaaattatcgatgagcgtggtggttatgccgatcgcgtcacactacgtctgaacgtcgaaaacccgaaactgtggagcgccgaaatcccgaatctctatcgtgcggtggttgaactgcacaccgccgacggcacgctgattgaagcagaagcctgcgatgtcggtttccgcgaggtgcggattgaaaatggtctgctgctgctgaacggcaagccgttgctgattcgaggcgttaaccgtcacgagcatcatcctctgcatggtcaggtcatggatgagcagacgatggtgcaggatatcctgctgatgaagcagaacaactttaacgccgtgcgctgttcgcattatccgaaccatccgctgtggtacacgctgtgcgaccgctacggcctgtatgtggtggatgaagccaatattgaaacccacggcatggtgccaatgaatcgtctgaccgatgatccgcgctggctaccggcgatgagcgaacgcgtaacgcgaatggtgcagcgcgatcgtaatcacccgagtgtgatcatctggtcgctggggaatgaatcaggccacggcgctaatcacgacgcgctgtatcgctggatcaaatctgtcgatccttcccgcccggtgcagtatgaaggcggcggagccgacaccacggccaccgatattatttgcccgatgtacgcgcgcgtggatgaagaccagcccttcccggctgtgccgaaatggtccatcaaaaaatggctttcgctacctggagagacgcgcccgctgatcctttgcgaatacgcccacgcgatgggtaacagtcttggcggtttcgctaaatactggcaggcgtttcgtcagtatccccgtttacagggcggcttcgtctgggactgggtggatcagtcgctgattaaatatgatgaaaacggcaacccgtggtcggcttacggcggtgattttggcgatacgccgaacgatcgccagttctgtatgaacggtctggtctttgccgaccgcacgccgcatccagcgctgacggaagcaaaacaccagcagcagtttttccagttccgtttatccgggcaaaccatcgaagtgaccagcgaatacctgttccgtcatagcgataacgagctcctgcactggatggtggcgctggatggtaagccgctggcaagcggtgaagtgcctctggatgtcgctccacaaggtaaacagttgattgaactgcctgaactaccgcagccggagagcgccgggcaactctggctcacagtacgcgtagtgcaaccgaacgcgaccgcatggtcagaagccgggcacatcagcgcctggcagcagtggcgtctggcggaaaacctcagtgtgacgctccccgccgcgtcccacgccatcccgcatctgaccaccagcgaaatggatttttgcatcgagctgggtaataagcgttggcaatttaaccgccagtcaggctttctttcacagatgtggattggcgataaaaaacaactgctgacgccgctgcgcgatcagttcacccgtgcaccgctggataacgacattggcgtaagtgaagcgacccgcattgaccctaacgcctgggtcgaacgctggaaggcggcgggccattaccaggccgaagcagcgttgttgcagtgcacggcagatacacttgctgatgcggtgctgattacgaccgctcacgcgtggcagcatcaggggaaaaccttatttatcagccggaaaacctaccggattgatggtagtggtcaaatggcgattaccgttgatgttgaagtggcgagcgatacaccgcatccggcgcggattggcctgaactgccagctggcgcaggtagcagagcgggtaaactggctcggattagggccgcaagaaaactatcccgaccgccttactgccgcctgttttgaccgctgggatctgccattgtcagacatgtataccccgtacgtcttcccgagcgaaaacggtctgcgctgcgggacgcgcgaattgaattatggcccacaccagtggcgcggcgacttccagttcaacatcagccgctacagtcaacagcaactgatggaaaccagccatcgccatctgctgcacgcggaagaaggcacatggctgaatatcgacggtttccatatggggattggtggcgacgactcctggagcccgtcagtatcggcggaatttcagctgagcgccggtcgctaccattaccagttggtctggtgtcaaaaataa
BBa_K105012_sequence
1
ggtgaaaatttgtattttcaatctggtggt
BBa_I732005_sequence
1
atgaccatgattacggattcactggccgtcgttttacaacgtcgtgactgggaaaaccctggcgttacccaacttaatcgccttgcagcacatccccctttcgccagctggcgtaatagcgaagaggcccgcaccgatcgcccttcccaacagttgcgcagcctgaatggcgaatggcgctttgcctggtttccggcaccagaagcggtgccggaaagctggctggagtgcgatcttcctgaggccgatactgtcgtcgtcccctcaaactggcagatgcacggttacgatgcgcccatctacaccaacgtgacctatcccattacggtcaatccgccgtttgttcccacggagaatccgacgggttgttactcgctcacatttaatgttgatgaaagctggctacaggaaggccagacgcgaattatttttgatggcgttaactcggcgtttcatctgtggtgcaacgggcgctgggtcggttacggccaggacagtcgtttgccgtctgaatttgacctgagcgcatttttacgcgccggagaaaaccgcctcgcggtgatggtgctgcgctggagtgacggcagttatctggaagatcaggatatgtggcggatgagcggcattttccgtgacgtctcgttgctgcataaaccgactacacaaatcagcgatttccatgttgccactcgctttaatgatgatttcagccgcgctgtactggaggctgaagttcagatgtgcggcgagttgcgtgactacctacgggtaacagtttctttatggcagggtgaaacgcaggtcgccagcggcaccgcgcctttcggcggtgaaattatcgatgagcgtggtggttatgccgatcgcgtcacactacgtctgaacgtcgaaaacccgaaactgtggagcgccgaaatcccgaatctctatcgtgcggtggttgaactgcacaccgccgacggcacgctgattgaagcagaagcctgcgatgtcggtttccgcgaggtgcggattgaaaatggtctgctgctgctgaacggcaagccgttgctgattcgaggcgttaaccgtcacgagcatcatcctctgcatggtcaggtcatggatgagcagacgatggtgcaggatatcctgctgatgaagcagaacaactttaacgccgtgcgctgttcgcattatccgaaccatccgctgtggtacacgctgtgcgaccgctacggcctgtatgtggtggatgaagccaatattgaaacccacggcatggtgccaatgaatcgtctgaccgatgatccgcgctggctaccggcgatgagcgaacgcgtaacgcgaatggtgcagcgcgatcgtaatcacccgagtgtgatcatctggtcgctggggaatgaatcaggccacggcgctaatcacgacgcgctgtatcgctggatcaaatctgtcgatccttcccgcccggtgcagtatgaaggcggcggagccgacaccacggccaccgatattatttgcccgatgtacgcgcgcgtggatgaagaccagcccttcccggctgtgccgaaatggtccatcaaaaaatggctttcgctacctggagagacgcgcccgctgatcctttgcgaatacgcccacgcgatgggtaacagtcttggcggtttcgctaaatactggcaggcgtttcgtcagtatccccgtttacagggcggcttcgtctgggactgggtggatcagtcgctgattaaatatgatgaaaacggcaacccgtggtcggcttacggcggtgattttggcgatacgccgaacgatcgccagttctgtatgaacggtctggtctttgccgaccgcacgccgcatccagcgctgacggaagcaaaacaccagcagcagtttttccagttccgtttatccgggcaaaccatcgaagtgaccagcgaatacctgttccgtcatagcgataacgagctcctgcactggatggtggcgctggatggtaagccgctggcaagcggtgaagtgcctctggatgtcgctccacaaggtaaacagttgattgaactgcctgaactaccgcagccggagagcgccgggcaactctggctcacagtacgcgtagtgcaaccgaacgcgaccgcatggtcagaagccgggcacatcagcgcctggcagcagtggcgtctggcggaaaacctcagtgtgacgctccccgccgcgtcccacgccatcccgcatctgaccaccagcgaaatggatttttgcatcgagctgggtaataagcgttggcaatttaaccgccagtcaggctttctttcacagatgtggattggcgataaaaaacaactgctgacgccgctgcgcgatcagttcacccgtgcaccgctggataacgacattggcgtaagtgaagcgacccgcattgaccctaacgcctgggtcgaacgctggaaggcggcgggccattaccaggccgaagcagcgttgttgcagtgcacggcagatacacttgctgatgcggtgctgattacgaccgctcacgcgtggcagcatcaggggaaaaccttatttatcagccggaaaacctaccggattgatggtagtggtcaaatggcgattaccgttgatgttgaagtggcgagcgatacaccgcatccggcgcggattggcctgaactgccagctggcgcaggtagcagagcgggtaaactggctcggattagggccgcaagaaaactatcccgaccgccttactgccgcctgttttgaccgctgggatctgccattgtcagacatgtataccccgtacgtcttcccgagcgaaaacggtctgcgctgcgggacgcgcgaattgaattatggcccacaccagtggcgcggcgacttccagttcaacatcagccgctacagtcaacagcaactgatggaaaccagccatcgccatctgctgcacgcggaagaaggcacatggctgaatatcgacggtttccatatggggattggtggcgacgactcctggagcccgtcagtatcggcggaatttcagctgagcgccggtcgctaccattaccagttggtctggtgtcaaaaataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z