BBa_K1122674
1
BBa_K1122674
Plac+fused PDC-ADH
2013-08-21T11:00:00Z
2015-05-08T01:09:15Z
Synthetic
lac promoter plus PDC-ADH fusion protein for ethanol production
false
false
_1433_
0
837
163
In stock
true
None
false
Aleksandra Lewicka, Jan Lyczakowski
component2373020
1
BBa_J33207
component2373021
1
BBa_K1122673
annotation2373020
1
BBa_J33207
range2373020
1
1
600
annotation2373021
1
BBa_K1122673
range2373021
1
609
3622
BBa_K1122673
1
pET fusion
Ethanol production module
2013-08-15T11:00:00Z
2015-05-08T01:09:15Z
''Z. mobilis'' gDNA codon optimised for ''E. coli''
This part codes for the fusion of Pyruvate decarboxylase and Alcohol dehydrogenase from ''Zymomonas mobilis''. Fused enzymes increase ethanol yields and enable its faster production.
false
false
_1433_
0
18014
9
It's complicated
true
The part is based on the BBa_K173003 - the enzymatic components of this BioBrick were fused using MABEL technology. The fusion removed start codon in adhB, stop codon in pdc and the RBS inbetween.
false
Aleksandra Lewicka, Jan Lyczakowski
BBa_J33207
1
BBa_J33207
lac promoter and lacZ
2006-10-26T11:00:00Z
2015-08-31T04:08:46Z
The DNA was amplified from E. coli BL21 genomic DNA using primers based on published sequence (Genbank accession J01636, gi:146575). The annotation shown here is based on that associated with this Genbank entry. The sequence shown here is derived by sequencing the construct.
This part (submitted in pSB1A2) consists of the lac promoter and lacZ' gene, encoding the N-terminal 76 amino acid residues of LacZ, sufficient to complement the lacZ-delta-M15 mutation for blue-white selection on Xgal plates. A SacI site has been introduced at the 3' end, overlapping the XbaI site of the Biobrick prefix. This is designed to be used as a cloning vector for making new biobricks. PCR primers can be designed with a SacI site in one primer and an SpeI site in the other. This removes the necessity for an excessively long non-complementary tail on one primer bearing either the full biobrick prefix or suffix. The PCR product can then be digested with SacI and SpeI for insertion into this plasmid, replacing the Plac-lacZ' cassette. Recombinant plasmids will then be white on IPTG/Xgal plates, whereas any that still contain the original insert will be blue. We have used this strategy to prepare several biobricks, including BBa_J33204, which contains the xylE gene encoding catechol-2,3-dioxygenase. (For making biobricks that contain lacZ', BBa_J33204 can be used in the same way; in this case, clones with plasmids that still contain xylE will turn yellow on addition of a drop of 10 mM catechol.)
false
false
_63_
0
837
63
It's complicated
true
Note that the SacI site overlaps the SpeI site. The Biobrick prefix ends ...TCTAGAG. When this is added to the CTC at the start of the sequence shown here, the SacI site, GAGCTC, is generated.
false
Chris French
annotation1907858
1
lacZ'
range1907858
1
370
600
annotation1907860
1
-35
range1907860
1
297
302
annotation1907857
1
rbs
range1907857
1
359
362
annotation1907856
1
LacI binding site
range1907856
1
332
352
annotation1907859
1
-10
range1907859
1
320
325
annotation1907854
1
SacI
range1907854
1
1
3
annotation1907855
1
CAP binding site
range1907855
1
248
285
BBa_K1122674_sequence
1
ctcatgttatatcccgccgttaaccaccatcaaacaggattttcgcctgctggggcaaaccagcgtggaccgcttgctgcaactctctcagggccaggcggtgaagggcaatcagctgttgcccgtctcactggtgaaaagaaaaaccaccctggcgcccaatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtgagcgcaacgcaattaatgtgagttagctcactcattaggcaccccaggctttacactttatgcttccggctcgtatgttgtgtgaaattgtgagcggataacaatttcacacaggaaacagctatgaccatgattacggattcactggccgtcgttttacaacgtcgtgactgggaaaaccctggcgttacccaacttaatcgccttgcagcacatccccctttcgccagctggcgtaatagcgaagaggcccgcaccgatcgcccttcccaacagttgcgcagcctgaatggcgaatggcgctttgcctggtttccggcaccagaagcggtgccggaaagctggctggagtgatactagagattaaagaggagaaatactagatgtcttataccgtggggacctatctggcagaacgcctggttcaaattgggctgaaacaccacttcgctgttgccggtgattataacctggtgctgctggacaatctgctgctgaataaaaacatggagcaagtctattgctgtaacgaactgaactgtggctttagcgctgaaggctatgcccgtgccaaaggtgccgccgctgctgttgtaacctatagtgtgggtgccctgagtgctttcgatgctattggaggggcttatgctgaaaacctgccggtaatcctgatttctggtgccccgaacaataacgatcatgccgccggtcatgtgctgcatcatgctctgggtaaaaccgactatcattatcagctggaaatggccaaaaacattactgccgctgccgaggcgatttatactccggaagaggctccggccaaaattgatcatgtcatcaaaaccgcactgcgtgagaaaaaaccggtctatctggaaattgcttgtaacattgcctcaatgccgtgtgccgctcctggtccggctagtgccctgtttaacgatgaagcttcggatgaagcaagcctgaatgctgccgttgaagaaacgctgaaattcattgccaaccgtgacaaagtcgctgtactggtgggttctaaactgcgcgctgctggtgctgaggaagccgctgtaaaattcgctgacgccctgggtggagctgtagcaaccatggctgccgccaaatccttctttcctgaggagaatcctcattatatcggcacgagctggggcgaggtttcatatccaggggtggagaaaaccatgaaagaggcagacgccgttatcgctctggctcctgtgttcaatgactattccaccaccgggtggactgatattcctgacccgaaaaaactggtgctggctgaacctcgttctgttgtggtgaatggcatccgttttccgagcgttcacctgaaagactatctgactcgtctggcccaaaaagtgtccaaaaaaactggcgctctggacttctttaaaagtctgaatgccggggaactgaaaaaagctgctccggccgatccttctgctcctctggttaatgccgagattgctcgtcaagttgaagctctgctgactccgaataccaccgttatcgccgaaactggtgattcctggttcaatgcccagcgtatgaaactgccgaatggtgctcgtgttgagtatgagatgcaatggggccatattggttggtctgtgcctgctgcttttggttatgccgttggtgctcctgaacgtcgtaacatcctgatggtaggggatggatcatttcaactgaccgcccaggaagttgctcaaatggttcgtctgaaactgcctgtgatcatctttctgattaacaactatggctatacgatcgaggtcatgattcacgatggtccgtataacaacattaaaaactgggactatgctggtctgatggaggtgttcaatggtaatggcgggtatgattctggagccgggaaaggcctgaaagcgaaaaccgggggtgagctggctgaggctattaaagttgccctggccaatacagatgggcctaccctgatcgaatgctttattgggcgtgaggactgtacagaagaactggtaaaatgggggaaacgtgttgccgctgctaacagccgtaaaccggtgaataaactgctggcatcaagcaccttttatatcccgtttgttaatgaaatgggcgagggttctctggaaaaagcgatcaaagacctgaatggtagtgggttcaaaaatgccctgattgtgtcagacgccttcatgaataaaagtggcgtggtgaaacaggttgctgatctgctgaaagcacagggtatcaatagcgccgtgtatgacggtgttatgccgaatccgaccgttacagccgtactggagggactgaaaatcctgaaagacaacaacagcgacttcgtgatttctctgggtggtggttctccacatgattgtgccaaagccattgccctggtggctacaaatggaggtgaagtgaaagattatgaggggatcgacaaaagcaaaaaaccggcactgcctctgatgagcatcaataccacagcgggtacagcatctgagatgactcgtttctgtattatcaccgacgaggttcgccatgtgaaaatggccatcgtggatcgtcatgttacaccgatggttagcgtgaatgatcctctgctgatggtgggtatgcctaaagggctgactgccgctacaggaatggacgccctgactcatgccttcgaagcctattctagcaccgccgctactcctattaccgacgcttgtgccctgaaagctgcctctatgattgccaaaaatctgaaaaccgcttgtgacaacggcaaagacatgcctgctcgtgaggccatggcctatgcccaatttctggccggtatggcgtttaataacgcctctctgggctatgttcatgctatggctcaccaactgggaggctattataacctgccacacggcgtctgtaatgctgtgctgctgcctcatgttctggcctataatgccagcgtggttgctggtcgcctgaaagatgttggagtggctatgggtctggatattgccaatctgggggacaaagagggtgctgaagcgacaattcaagccgtccgtgacctggctgcttctatcggaatcccggcaaacctgacagaactgggcgccaaaaaagaagatgtgcctctgctggctgatcatgctctgaaagacgcttgtgctctgactaatcctcgtcagggagatcagaaagaagtcgaggagctgtttctgagtgccttttgataatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_K1122673_sequence
1
attaaagaggagaaatactagatgtcttataccgtggggacctatctggcagaacgcctggttcaaattgggctgaaacaccacttcgctgttgccggtgattataacctggtgctgctggacaatctgctgctgaataaaaacatggagcaagtctattgctgtaacgaactgaactgtggctttagcgctgaaggctatgcccgtgccaaaggtgccgccgctgctgttgtaacctatagtgtgggtgccctgagtgctttcgatgctattggaggggcttatgctgaaaacctgccggtaatcctgatttctggtgccccgaacaataacgatcatgccgccggtcatgtgctgcatcatgctctgggtaaaaccgactatcattatcagctggaaatggccaaaaacattactgccgctgccgaggcgatttatactccggaagaggctccggccaaaattgatcatgtcatcaaaaccgcactgcgtgagaaaaaaccggtctatctggaaattgcttgtaacattgcctcaatgccgtgtgccgctcctggtccggctagtgccctgtttaacgatgaagcttcggatgaagcaagcctgaatgctgccgttgaagaaacgctgaaattcattgccaaccgtgacaaagtcgctgtactggtgggttctaaactgcgcgctgctggtgctgaggaagccgctgtaaaattcgctgacgccctgggtggagctgtagcaaccatggctgccgccaaatccttctttcctgaggagaatcctcattatatcggcacgagctggggcgaggtttcatatccaggggtggagaaaaccatgaaagaggcagacgccgttatcgctctggctcctgtgttcaatgactattccaccaccgggtggactgatattcctgacccgaaaaaactggtgctggctgaacctcgttctgttgtggtgaatggcatccgttttccgagcgttcacctgaaagactatctgactcgtctggcccaaaaagtgtccaaaaaaactggcgctctggacttctttaaaagtctgaatgccggggaactgaaaaaagctgctccggccgatccttctgctcctctggttaatgccgagattgctcgtcaagttgaagctctgctgactccgaataccaccgttatcgccgaaactggtgattcctggttcaatgcccagcgtatgaaactgccgaatggtgctcgtgttgagtatgagatgcaatggggccatattggttggtctgtgcctgctgcttttggttatgccgttggtgctcctgaacgtcgtaacatcctgatggtaggggatggatcatttcaactgaccgcccaggaagttgctcaaatggttcgtctgaaactgcctgtgatcatctttctgattaacaactatggctatacgatcgaggtcatgattcacgatggtccgtataacaacattaaaaactgggactatgctggtctgatggaggtgttcaatggtaatggcgggtatgattctggagccgggaaaggcctgaaagcgaaaaccgggggtgagctggctgaggctattaaagttgccctggccaatacagatgggcctaccctgatcgaatgctttattgggcgtgaggactgtacagaagaactggtaaaatgggggaaacgtgttgccgctgctaacagccgtaaaccggtgaataaactgctggcatcaagcaccttttatatcccgtttgttaatgaaatgggcgagggttctctggaaaaagcgatcaaagacctgaatggtagtgggttcaaaaatgccctgattgtgtcagacgccttcatgaataaaagtggcgtggtgaaacaggttgctgatctgctgaaagcacagggtatcaatagcgccgtgtatgacggtgttatgccgaatccgaccgttacagccgtactggagggactgaaaatcctgaaagacaacaacagcgacttcgtgatttctctgggtggtggttctccacatgattgtgccaaagccattgccctggtggctacaaatggaggtgaagtgaaagattatgaggggatcgacaaaagcaaaaaaccggcactgcctctgatgagcatcaataccacagcgggtacagcatctgagatgactcgtttctgtattatcaccgacgaggttcgccatgtgaaaatggccatcgtggatcgtcatgttacaccgatggttagcgtgaatgatcctctgctgatggtgggtatgcctaaagggctgactgccgctacaggaatggacgccctgactcatgccttcgaagcctattctagcaccgccgctactcctattaccgacgcttgtgccctgaaagctgcctctatgattgccaaaaatctgaaaaccgcttgtgacaacggcaaagacatgcctgctcgtgaggccatggcctatgcccaatttctggccggtatggcgtttaataacgcctctctgggctatgttcatgctatggctcaccaactgggaggctattataacctgccacacggcgtctgtaatgctgtgctgctgcctcatgttctggcctataatgccagcgtggttgctggtcgcctgaaagatgttggagtggctatgggtctggatattgccaatctgggggacaaagagggtgctgaagcgacaattcaagccgtccgtgacctggctgcttctatcggaatcccggcaaacctgacagaactgggcgccaaaaaagaagatgtgcctctgctggctgatcatgctctgaaagacgcttgtgctctgactaatcctcgtcagggagatcagaaagaagtcgaggagctgtttctgagtgccttttgataatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_J33207_sequence
1
ctcatgttatatcccgccgttaaccaccatcaaacaggattttcgcctgctggggcaaaccagcgtggaccgcttgctgcaactctctcagggccaggcggtgaagggcaatcagctgttgcccgtctcactggtgaaaagaaaaaccaccctggcgcccaatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtgagcgcaacgcaattaatgtgagttagctcactcattaggcaccccaggctttacactttatgcttccggctcgtatgttgtgtgaaattgtgagcggataacaatttcacacaggaaacagctatgaccatgattacggattcactggccgtcgttttacaacgtcgtgactgggaaaaccctggcgttacccaacttaatcgccttgcagcacatccccctttcgccagctggcgtaatagcgaagaggcccgcaccgatcgcccttcccaacagttgcgcagcctgaatggcgaatggcgctttgcctggtttccggcaccagaagcggtgccggaaagctggctggagtga
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z