BBa_K1154002
1
IGPD
Saccharomyces cerevisiae imidazoleglycerol-phosphate dehydratase (IGPD)
2013-09-16T11:00:00Z
2015-05-08T01:09:29Z
Coding sequence is from the HIS3/YOR202W locus on yeast chromosome XV from coordinates 721946 to 722608.
The Saccharomyces cerevisiae HIS3 gene encodes imidazoleglycerol-phosphate dehydratase (IGPD), which catalyzes the interconversion of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate and 3-(imidazol-4-yl)-2-oxopropyl phosphate plus H2O. The dehydration reaction is a key step in the biosynthesis of histidine in many bacteria, fungi and plants. The gene is routinely used as a selectable marker in yeast histidine auxotrophs harboring a genomic his3 mutation (e.g., his3-delta1). Although, it also compliments Escherichia coli hisB mutations (e.g., ΔhisB720::kan).
false
false
_1466_
0
12086
9
Not in stock
false
na
false
Adam Nighswander, Tanner Reeb and Bianca Maled
BBa_K1154002_sequence
1
atgactgaacaaaaagctttggttaaaagaattactaatgaaactaaaattcaaattgctatttctttgaaaggtggtccattggctattgaacattctatttttccagaaaaagaagctgaagctgttgctgaacaagctactcaatctcaagttattaatgttcatactggtattggttttttggatcatatgattcatgctttggctaaacattctggttggtctttgattgttgaatgtattggtgatttgcatattgatgatcatcatactactgaagattgtggtattgctttgggtcaagcttttaaagaagctttgggtgctgttagaggtgttaaaagatttggttctggttttgctccattggatgaagctttgtcaagagctgttgttgatttgtctaatagaccatatgctgttgttgaattgggtttgcaaagagaaaaagttggtgatttgtcttgtgaaatgattccacattttttggaatcttttgctgaagcttcaagaattactttgcatgttgattgtttgagaggtaaaaatgatcatcatagatctgaatctgcttttaaagctttggctgttgctattagagaagctacttctccaaatggtactaatgatgttccatctactaaaggtgttttgatgtaa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z