BBa_K1164002
1
BBa_K1164002
LacI repressor tagged with yBFP
2013-09-15T11:00:00Z
2015-05-08T01:09:32Z
E.coli/commercial synthesis
This is the LacI repressor from E.coli tagged with yeast codon optimized BFP. LacI will bind with high specificity to the the operator lacO and is inhibited in the presence of IPTG. BFP is a monomeric fluorescent protein that has an excitation peak of 399 nm and an emission peak of 465 nm. It was yeast codon optimized through DNA synthesis for the purpose of expressing in S. cerevisiae tagged to various repressors and activators.
This is an updated version of BBa_K642001 that is functional in S. cerevisiae.
false
false
_1476_
0
10002
9
It's complicated
false
In order to remove the illegal XbaI site, site-directed mutagenesis was performed, changing nucleotide 255 from a thymine to a cytosine, and also changing nucleotide 258 from an adenine to a glycine.
false
Wilson Lam, Dylan Siriwardena
annotation2346173
1
lacI
range2346173
1
1
1080
annotation2346174
1
yBFP
range2346174
1
1081
1782
BBa_K1164002_sequence
1
atgaaaccagtaacattgtatgatgtcgcagagtatgccggtgtctcttatcagactgtttccagagtggtgaaccaggccagccatgtttctgccaaaaccagggaaaaagtggaagcagccatggcagagctgaattacattcccaacagagtggcacaacaactggcaggcaaacagagcttgctgattggagttgccacctccagtctggccctgcatgcaccatctcaaattgtggcagccattaaatccagggctgatcaactgggagcctctgtggtggtgtcaatggtagaaagaagtggagttgaagcctgtaaagctgctgtgcacaatcttctggcacaaagagtcagtgggctgatcattaactatccactggatgaccaggatgccattgctgtggaagctgcctgcactaatgttccagcactctttcttgatgtctctgaccagacacccatcaacagtattattttctcccatgaagatggtacaagactgggtgtggagcatctggttgcattgggacaccagcaaattgcactgcttgcgggcccactcagttctgtctcagcaaggctgagactggccggctggcataaatatctcactaggaatcaaattcagccaatagctgaaagagaaggggactggagtgccatgtctgggtttcaacaaaccatgcaaatgctgaatgagggcattgttcccactgcaatgctggttgccaatgatcagatggcactgggtgcaatgagagccattactgagtctgggctgagagttggtgcagatatctcggtagtgggatacgacgataccgaagacagctcatgttatatcccgccgttaaccaccatcaaacaggattttcgcctgctggggcaaaccagcgtggaccgcttgctgcaactctctcagggccaggcggtgaagggcaatcagctgttgccagtctcactggtgaagagaaaaaccaccctggcacccaatacacaaactgcctctccccgggcattggctgattcactcatgcagctagcaagacaggtttccagactggaaagtgggcagatgtccgaagaattgatcaaggaaaacatgcacatgaaattgtatatggaaggtactgtcgacaaccaccacttcaaatgcacctccgaaggtgaaggtaaaccttatgaaggtacacaaaccatgagaatcaaagtcgtcgaaggtggtccattgccatttgctttcgacattttggccacatctttcttgtatggttccaaaactttcatcaatcacacccaaggtattccagacttctttaaacaatctttccctgaaggtttcacttgggaaagagtcaccacctatgaagatggtggtgtcttgactgctactcaagacacatccttacaagacggttgcttgatctataacgtcaagattagaggtgtcaacttcacatcaaacggtcctgtcatgcaaaaaaagacattgggttgggaagctttcaccgaaactttgtatcctgccgacggtggtttagaaggtagaaacgacatggccttaaaattggtcggtggtagtcacttgattgccaacatcaaaacaacctatagatccaaaaaacctgccaaaaacttgaaaatgcctggtgtctattatgtcgactatagattggaaagaattaaggaagccaacaacgaaacttatgtcgaacaacacgaagttgctgtcgccagatattgtgacttgccttcaaaattgggtcacaaattgaac
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z