BBa_K1176888
1
BBa_K1176888
Mtd (BPP-1 bacteriophage)
2013-08-28T11:00:00Z
2015-05-08T01:09:35Z
This part is naturally occurring in the genomic DNA of the Bordetella BPP-1 bacteriophage. Citation: Overstreet, C. M., Yuan, T. Z., Levin, A. M., Kong, C., Coroneus, J. G., & Weiss, G. a. (2012). Self-made phage libraries with heterologous inserts in the Mtd of Bordetella bronchiseptica. Protein engineering, design & selection : PEDS, 25(4), 145???51. doi:10.1093/protein/gzr068
This part codes for the Major Tropism Determinant (mtd) protein responsible for selective protein binding to the surface markers on Bordetella bacteria. It has several specific nucleotides in its sequence that can be mutagenized to change the binding properties of the protein without adversely affecting the folding and stability of the protein.
false
false
_1489_
0
18032
9
It's complicated
false
In designing this part, we had to alter 3 restriction sites naturally occurring in the sequence: PstI, EcoRI, and NotI.
false
Michael Cheng
BBa_K1176888_sequence
1
atgagtaccgcagtccagttccgcggcggcacgaccgcccagcacgccacgttcacgggcgccgcccgtgagattaccgtcgataccgacaagaacacggtcgttgtgcatgacggtgccaccgctggcggcttccccctggcgcggcacgatctggtgaaaacggctttcatcaaggccgacaagtcggccgtcgccttcacgcgcaccggcaacgcaacggccagcatcaaggctggcaccatcgtggaggtcaacggcaagctggtgcagttcaccgccgacacggccatcaccatgccggcgctgacggccggcaccgactacgccatctacgtctgcgacgatggcacggtgcgcgccgattccaacttttcggcgcccactggctacacctcgaccacggcgcgcaaggtgggcggcttccactatgcgccgggaagcaacgcggcagcgcaggctggcggaaacaccacggcgcagatcaacgaatacagcctgtgggacatcaagttccgcccggctgcgctcgacccgcgcggcatgacgctggtggccggcgcgttttgggcggacatctatctgctaggcgtcaaccacctgaccgatggcaccagcaaatacaacgtgaccatcgcggacggcagcgcgtccccgaagaaatctaccaagttcggcggcgacggcagcgcggcctacagcgacggcgcctggtacaacttcgccgaggtcatgactcaccacggcaagcgcctgcccaactacaacgagttccaggcgctggctttcggcacgaccgaggctacgtccagcggcggcaccgacgtgcccaccaccggcgtgaacggcacgggcgccacgagcgcgtggaacatcttcacgtccaagtggggcgttgtgcaggcgtccggttgcttgtggacgtggggtaacgagttcggcggcgtgaatggcgcatccgaatacacggccaacactggaggccgcggatcggtgtacgcccagcccgctgctgcgctattcggcggcgcctggaacggcacgtcgctctcgggttctcgcgctgcgctctggtacagcgggccgtcgttctcgttcgcgttcttcggggcgcgcggcgtctgtgaccacctgattcttgag
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z