BBa_K1230000
1
MarA
AcrAB-TolC multidrug efflux transport system activator from E. coli
2013-09-07T11:00:00Z
2015-05-08T01:09:44Z
Synthesis from genscript
The MarA protein acts as a transcriptional activator in E. coli, it allows the expression of the acrAB and tolC operons, which activate the AcrAB-TolC efflux pump, a mechanism that has been related with resistance to organic solvents, dyes, detergents, antibiotics such as chloramphenicol, tetracycline, novobiocin, erythromycin, fusidic acid and cloxacillin, as well as to cationic antimicrobial peptides, such as LL-37, HNP-2 and HBD-1.
false
false
_1544_
0
17080
9
It's complicated
false
Silent mutation (G->C) at base 132 to remove AarI and BspMI sites.
false
Andr??s Ferri??o Iriarte
annotation2335366
1
stop
range2335366
1
388
393
annotation2335367
1
start
range2335367
1
1
3
annotation2335365
1
MarA
range2335365
1
1
393
annotation2335368
1
G to C mutation
range2335368
1
132
132
BBa_K1230000_sequence
1
atgacgatgtccagacgcaatactgacgctattaccattcatagcattttggactggatcgaggacaacctggaatcgccactgtcactggagaaagtgtcagagcgttcgggttactccaaatggcacctccaacggatgtttaaaaaagaaaccggtcattcattaggccaatacatccgcagccgtaagatgacggaaatcgcgcaaaagctgaaggaaagtaacgagccgatactctatctggcagaacgatatggcttcgagtcgcaacaaactctgacccgaaccttcaaaaattactttgatgttccgccgcataaataccggatgaccaatatgcagggcgaatcgcgctttttacatccattaaatcattacaacagctaataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z