BBa_K131001
1
BBa_K131001
ColE2 SOS Promoter
2008-07-21T11:00:00Z
2015-05-08T01:09:47Z
This part comes from the ColE2 operon, which came from a plasmid.
This promoter normally represses the ColE2 activity gene, ceaB, in the ColE2 operon.
To activate this promoter would require a RecA positive strain, as the protein LexA represses the promoter. To induce this promoter, an intercalating agent, mitomycin C, was utilized to induce the SOS response, and thus the expression of the genes under control of this promoter.
true
false
_259_
0
1917
9
Discontinued
false
Lab strains of E. coli, such as Top10 from Invitrogen, are deficient in RecA so we required a RecA positive strain to induce this promoter. We used BL21 from Novagen.
false
Kevin McLeod
annotation1968167
1
SOS Box
range1968167
1
252
267
annotation1968164
1
-35 Signal
range1968164
1
218
224
annotation1968166
1
Region of Dyad Symmetry
range1968166
1
136
161
annotation1968165
1
-15 Signal
range1968165
1
241
246
BBa_K131001_sequence
1
aactcggttttaatcagacctggcatgagtggaagcgggacgaacagcacaggcaacaacaacgccgccccgggcacttccggggcatgagtatgtgatatccggggctgcaccccggaccccgccaacacatcacgggccacaaaattttttgtggcccgctctgcgttttctaagtgttatccctcctgatttctaaaaaattttccacctgaacttgacagaaaaaacgatgacgggtactttttgatctgtacataaaaccag
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z