BBa_K1317004
1
BBa_K1317004
Fusion protein RFP + Elastin like polypeptide (ELP)
2014-10-06T11:00:00Z
2015-05-08T01:09:50Z
The source of this part is BBa_K1317003.
The ELP presents specific properties: it precipitates at high temperature. This property can be used for thermal cycling purification for instance. By successive cycles of temperature, ELP can be purified from a mix of proteins.
This special property has been used to create a composite part for the iGEM registry. It is a proof of concept of the use of this part as a tool for protein purification by fusing ELP to another protein.
The protein used as an example is RFP, to ease vizualisation of the process.
false
false
_1692_
0
20045
9
Not in stock
false
This part has been assembled by chew back assembly (cf wiki page: )
In-silico cloning and design have been performed on Genome Compiler.
false
Mounir Benkoulouche
component2423563
1
BBa_K1317003
component2423566
1
BBa_E1010
annotation2423566
1
BBa_E1010
range2423566
1
340
1045
annotation2423563
1
BBa_K1317003
range2423563
1
1
333
BBa_K1317003
1
BBa_K1317003
CDS for Elastin like polypeptide (ELP)
2014-10-06T11:00:00Z
2015-05-08T01:09:50Z
Next
Next
false
false
_1692_
0
20045
9
It's complicated
false
Next
false
Mounir Benkoulouche
annotation2399855
1
Chew Back
range2399855
1
324
329
annotation2399396
1
ELP20
range2399396
1
6
332
annotation2399398
1
Stop codon
range2399398
1
330
332
annotation2399397
1
Start Codon
range2399397
1
6
8
annotation2399399
1
Aromatic (dosage)
range2399399
1
9
11
annotation2399400
1
NheI
range2399400
1
312
317
BBa_E1010
1
mRFP1
**highly** engineered mutant of red fluorescent protein from Discosoma striata (coral)
2004-07-27T11:00:00Z
2015-08-31T04:07:26Z
Campbell et al., PNAS v99 p7877 <a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=12060735">URL</a>
Released HQ 2013
monomeric RFP:
Red Fluorescent Protein.
Excitation peak: 584 nm
Emission peak: 607 nm
false
false
_11_1_
0
52
7
In stock
false
TAATAA double stop codon added (DE).
Four silent mutations made to remove three EcoRI sites and one PstI site: A28G, A76G, A349G, G337A.
true
Drew Endy
annotation1014044
1
mrfp1
range1014044
1
1
675
annotation2214014
1
Help:Barcodes
range2214014
1
682
706
BBa_K1317003_sequence
1
ctagaatgtgggggcccggaggagtaggtcccttaggggtggggcccttgcaacagggccctggaggttacggccccggtggcgtgggcccacttggtgtgggacctctccagcaaggccctggaggttatggtccggggggagtcggcccactaggtgttgggccgttgcagcaagggccggggggttatggaccaggtggcgttggtccgttaggagtaggaccgttgcagcagggcccgggtggctatggacctggcggcgttggtccacttggtgtcggtcctctccagcaagggccggggggttacgctagcttatcatctagctaaa
BBa_E1010_sequence
1
atggcttcctccgaagacgttatcaaagagttcatgcgtttcaaagttcgtatggaaggttccgttaacggtcacgagttcgaaatcgaaggtgaaggtgaaggtcgtccgtacgaaggtacccagaccgctaaactgaaagttaccaaaggtggtccgctgccgttcgcttgggacatcctgtccccgcagttccagtacggttccaaagcttacgttaaacacccggctgacatcccggactacctgaaactgtccttcccggaaggtttcaaatgggaacgtgttatgaacttcgaagacggtggtgttgttaccgttacccaggactcctccctgcaagacggtgagttcatctacaaagttaaactgcgtggtaccaacttcccgtccgacggtccggttatgcagaaaaaaaccatgggttgggaagcttccaccgaacgtatgtacccggaagacggtgctctgaaaggtgaaatcaaaatgcgtctgaaactgaaagacggtggtcactacgacgctgaagttaaaaccacctacatggctaaaaaaccggttcagctgccgggtgcttacaaaaccgacatcaaactggacatcacctcccacaacgaagactacaccatcgttgaacagtacgaacgtgctgaaggtcgtcactccaccggtgcttaataacgctgatagtgctagtgtagatcgc
BBa_K1317004_sequence
1
ctagaatgtgggggcccggaggagtaggtcccttaggggtggggcccttgcaacagggccctggaggttacggccccggtggcgtgggcccacttggtgtgggacctctccagcaaggccctggaggttatggtccggggggagtcggcccactaggtgttgggccgttgcagcaagggccggggggttatggaccaggtggcgttggtccgttaggagtaggaccgttgcagcagggcccgggtggctatggacctggcggcgttggtccacttggtgtcggtcctctccagcaagggccggggggttacgctagcttatcatctagctaaatactagatggcttcctccgaagacgttatcaaagagttcatgcgtttcaaagttcgtatggaaggttccgttaacggtcacgagttcgaaatcgaaggtgaaggtgaaggtcgtccgtacgaaggtacccagaccgctaaactgaaagttaccaaaggtggtccgctgccgttcgcttgggacatcctgtccccgcagttccagtacggttccaaagcttacgttaaacacccggctgacatcccggactacctgaaactgtccttcccggaaggtttcaaatgggaacgtgttatgaacttcgaagacggtggtgttgttaccgttacccaggactcctccctgcaagacggtgagttcatctacaaagttaaactgcgtggtaccaacttcccgtccgacggtccggttatgcagaaaaaaaccatgggttgggaagcttccaccgaacgtatgtacccggaagacggtgctctgaaaggtgaaatcaaaatgcgtctgaaactgaaagacggtggtcactacgacgctgaagttaaaaccacctacatggctaaaaaaccggttcagctgccgggtgcttacaaaaccgacatcaaactggacatcacctcccacaacgaagactacaccatcgttgaacagtacgaacgtgctgaaggtcgtcactccaccggtgcttaataacgctgatagtgctagtgtagatcgc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z