BBa_K1319001
1
REACh1
RFC[25]-compatible dark quencher based on K1319000 (E0030)
2014-09-02T11:00:00Z
2015-05-08T01:09:50Z
The part was created by site-directed mutagenesis on K1319000 that we previously created from E0030
This part is a RFC[25] dark quencher that is based upon K1319000 (the RFC[25] version of E0030/EYFP).
Two mutations were introduced that eliminated fluorescence:
* L90I
* Y145W
=References=
* Ganesan S, Ameer-Beg SM, Ng TT, Vojnovic B, Wouters FS. A dark yellow
fluorescent protein (YFP)-based Resonance Energy-Accepting Chromoprotein (REACh)
for F??rster resonance energy transfer with GFP. Proc Natl Acad Sci U S A. 2006
Mar 14;103(11):4089-94. Epub 2006 Mar 6. PubMed PMID: 16537489; PubMed Central
PMCID: PMC1449651. [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1449651/?report=classic PubMed Central]
false
false
_1694_
0
19522
9
It's complicated
false
The Y145W mutation was introduced to eliminate fluorescence of the protein.
false
Michael Osthege, Florian Gohr
annotation2382579
1
REACh1
range2382579
1
1
711
BBa_K1319001_sequence
1
gtgagcaagggcgaggagctgttcaccggggtggtgcccatcctggtcgagctggacggcgacgtaaacggccacaagttcagcgtgtccggcgagggcgagggcgatgccacctacggcaagctgaccctgaagttcatctgcaccaccggcaagctgcccgtgccctggcccaccatcgtgaccaccttcggctacggcctgcaatgcttcgcccgctaccccgaccacatgaagctgcacgacttcttcaagtccgccatgcccgaaggctacgaccaggagcgcaccatcttcttcaaggacgacggcaactacaagacccgcgccgaggtgaagttcgagggcgacaccctggtgaaccgcatcgagctgaagggcatcgacttcaaggaggacggcaacatcctggggcacaagctggagtacaactggaacagccacaacgtctatatcatggccgacaagcagaagaacggcatcaaggtgaacttcaagatccgccacaacatcgaggacggcagcgtgcagctcgccgaccactaccagcagaacacccccatcggcgacggccccgtgctgctgcccgacaaccactacctgagctaccagtccgccctgagcaaagaccccaacgagaagcgcgatcacatggtcctgctggagttcgtgaccgccgccgggatcactctcggcatggacgagctgtac
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z