BBa_K133020
1
BBa_K133020
CMV-CF213-multiHP-CF215-RGD-Histop (term.)
2008-10-29T12:00:00Z
2015-05-08T01:09:55Z
plasmid
CMV-CF213-MULTI-CF215-RGD-HIS-STOP (term.)
false
true
_231_
0
3352
9
It's complicated
false
none
false
Ana Lasic
component1996093
1
BBa_K133046
component1996094
1
BBa_K133036
component1996090
1
BBa_I712004
component1996091
1
BBa_K133010
component1996092
1
BBa_K133139
annotation1996092
1
BBa_K133139
range1996092
1
1305
1829
annotation1996094
1
BBa_K133036
range1996094
1
2753
2782
annotation1996090
1
BBa_I712004
range1996090
1
1
654
annotation1996091
1
BBa_K133010
range1996091
1
661
1296
annotation1996093
1
BBa_K133046
range1996093
1
1836
2744
BBa_K133036
1
RGD-His-St
RGD-His affinity tag-Stop
2008-10-25T11:00:00Z
2015-05-08T01:09:55Z
Part was constructed by primer annealing.
This is His-tag with stop codon and RGD seguence. His-tag is used for detection of His-tagged proteins by anti-His antibodies. RGD is arginine-glycine-aspartic amino acid sequence, present on several extracellular matrix proteins. It is required for binding to integrins.
false
false
_231_
0
3350
9
It's complicated
false
Cloned into pSB1AK3 vector.
false
Jerneja Mori
BBa_K133010
1
BBa_K133010
CF213
2008-10-29T12:00:00Z
2015-05-08T01:09:55Z
Genomic DNA
Chimeric flagellin
false
false
_231_
0
3351
9
It's complicated
false
None
false
Vid Kocar
BBa_I712004
1
BBa_I712004
CMV promoter
2007-10-18T11:00:00Z
2015-08-31T04:07:45Z
pcDNA3 by Invitrogen
a constitutive expression promoter or use in mammalian cells. Ribosome binding site is included.
false
false
_130_
0
1896
9
It's complicated
false
Cloned into pSB1AC3 vector.
false
Andrej Ondracka
BBa_K133139
1
BBa_K133139
multiHP
2008-10-24T11:00:00Z
2015-05-08T01:09:57Z
false
false
_231_
0
1883
9
Not in stock
false
false
Katja Kolar
BBa_K133046
1
BBa_K133046
CF215
2008-10-29T12:00:00Z
2015-05-08T01:09:55Z
We used polimerase chain reaction from chimeric flagellin (BBa_K133016).
This is a part that is composed of C-terminal end of chimeric flagellin (BBa_K133016). We used aminoacids from 215th aminoacid on.
Chimeric flagellin is composed of C- and N-terminal part of E.coli flagellin and of variable region of H.pylori. The E.coli parts are responsible for binding and activation of cell membrane receptor TLR5 to initiate immune response, while H.pylori variable region was used to array the immune response against H.pylori.
This part was used in combination with CF213 - chimeric flagellin (BBa_K133010). Between the CF213 and CF215 we have put H.pylori antigens in order to array the immune response against H.pylori.
false
false
_231_
0
3352
9
It's complicated
false
It was important to split the chimeric flagellin in the variable region to assure that the antigen will be in the right place and not to interrupt the 3d structure of the protein.
false
Ana Lasic
BBa_K133010_sequence
1
atggcacaagtcattaataccaacagcctctcgctgatcactcaaaataatatcaacaagaaccagtctgcgctgtcgagttctatcgagcgtctgtcttctggcttgcgtattaacagcgcgaaggatgacgcagcgggtcaggcgattgctaaccgtttcacctctaacattaaaggcctgactcaggcggcccgtaacgccaacgacggtatctccgttgcgcagaccaccgaaggcgcgctgtccgaaatcaacaacaacttacagcgtgtgcgtgaactgacggtacaggccactaccggtactaactctgagtctgatctgtcttctatccaggacgaaattaaatcccgtctggatgaaattgaccgcgtatctggtcagacccagttcaacggcgtgaacgtgctggcaaaaaatggctccatgaaaatccaggttggcgcaaatgataaccagactatcactatcgatctgaagcagattgatgctaaaactcttggccttgatggttttagcgttaaagcgttaatcacggcttctggggatattagcttgacttttaaacaagtggatggcgtgaatgatgtaactttagagagcgtaaaagtttctagttcagcaggtacaggg
BBa_K133139_sequence
1
cacatggacatgcttatggtgtgccaccacttggataaaagcattaaagaagatgttcagttcgctgattcaaggatcggcaaactgaccgtgaccagcggccaaaaaacagaagttcaacccacgcaagtcattgatgggccttttgcgggtggcaaagacacggttgtcaatattgatcgcatcaacactaaagccgatggcacgattaaagtgggagggtttaaagcttctcttaccaccaacgcggctcatttgaatatcggcaaaggcggtgtcaatctgtccaatcaagcgagcgggcgcacccttttagtggaaaatctaaccgggaatatcaccgttgatgggcctttaagagtgaataatcaagtgggtggctatgctttggcaggatcaagcgcgaattttgaatttaaggctggtgtggatactaaaaacggcacagccactttcaataacggcaaactgaccgtgaccagcggcaaaaggaccatacagaaaaaatcagaacccgggttgtta
BBa_K133046_sequence
1
atgggtgtgttggcagaagtgattaacaaaaattctaaccgaacaggggttaaagcttatgcgagcgttatcaccacgagcgatgtggcggtccaatcaggaagtttgagtaatttaactttaaatgggatccatttgggtaatatcgcagatattaagaaaaatgactcagacggaaggttagtcgcagcgatcaatgcggttacttcagaaaccggcgtggaagcttatacggatcaaaaagggcgcttgaatttgcgcagtatagatggtcgtgggattgaaatcaaaaccgatagcgtcagtaatgggcctagtgctttaacgatggtcaatggcggtcaggatttaacaaaaggttctactaactatgggaggctttctctcacacgcttagacgctaaaagcatcaatgtcgtttcggcttctgattcgcaacatttaggtttcacagcgattggttttggggaatctcaagtggcagaaaccacggtgaatttgcgcgatgttactgggaattttaacgctaatgtcaaatcagccagtggcgcgaactataacgccgtgatcgctagcggtaaccaaagcttgggatctggggttacaaccttaagagctgttgcaaatggtaaaaccacggatccgctgaaagcgctggacgatgctatcgcatctgtagacaaattccgttcttccctcggtgcggtgcaaaaccgtctggattccgcggttactaacctgaacaacaccactaccaacctgtctgaagcgcagtcccgtattcaggacgccgactatgcgaccgaagtgtccaatatgtcgaaagcgcagatcatccagcaggccggtaactccgtgttggcaaaagctaaccaggtaccgcagcaggttctgtctctgttacagggt
BBa_I712004_sequence
1
cgatgtacgggccagatatacgcgttgacattgattattgcctagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggagtatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcggtttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccattgacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagagctctctggctaactagagaacccactgcttactggcttatcgaaat
BBa_K133020_sequence
1
cgatgtacgggccagatatacgcgttgacattgattattgcctagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggtaaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggtggagtatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcggtttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccattgacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagagctctctggctaactagagaacccactgcttactggcttatcgaaattactagatggcacaagtcattaataccaacagcctctcgctgatcactcaaaataatatcaacaagaaccagtctgcgctgtcgagttctatcgagcgtctgtcttctggcttgcgtattaacagcgcgaaggatgacgcagcgggtcaggcgattgctaaccgtttcacctctaacattaaaggcctgactcaggcggcccgtaacgccaacgacggtatctccgttgcgcagaccaccgaaggcgcgctgtccgaaatcaacaacaacttacagcgtgtgcgtgaactgacggtacaggccactaccggtactaactctgagtctgatctgtcttctatccaggacgaaattaaatcccgtctggatgaaattgaccgcgtatctggtcagacccagttcaacggcgtgaacgtgctggcaaaaaatggctccatgaaaatccaggttggcgcaaatgataaccagactatcactatcgatctgaagcagattgatgctaaaactcttggccttgatggttttagcgttaaagcgttaatcacggcttctggggatattagcttgacttttaaacaagtggatggcgtgaatgatgtaactttagagagcgtaaaagtttctagttcagcaggtacagggtactagagcacatggacatgcttatggtgtgccaccacttggataaaagcattaaagaagatgttcagttcgctgattcaaggatcggcaaactgaccgtgaccagcggccaaaaaacagaagttcaacccacgcaagtcattgatgggccttttgcgggtggcaaagacacggttgtcaatattgatcgcatcaacactaaagccgatggcacgattaaagtgggagggtttaaagcttctcttaccaccaacgcggctcatttgaatatcggcaaaggcggtgtcaatctgtccaatcaagcgagcgggcgcacccttttagtggaaaatctaaccgggaatatcaccgttgatgggcctttaagagtgaataatcaagtgggtggctatgctttggcaggatcaagcgcgaattttgaatttaaggctggtgtggatactaaaaacggcacagccactttcaataacggcaaactgaccgtgaccagcggcaaaaggaccatacagaaaaaatcagaacccgggttgttatactagatgggtgtgttggcagaagtgattaacaaaaattctaaccgaacaggggttaaagcttatgcgagcgttatcaccacgagcgatgtggcggtccaatcaggaagtttgagtaatttaactttaaatgggatccatttgggtaatatcgcagatattaagaaaaatgactcagacggaaggttagtcgcagcgatcaatgcggttacttcagaaaccggcgtggaagcttatacggatcaaaaagggcgcttgaatttgcgcagtatagatggtcgtgggattgaaatcaaaaccgatagcgtcagtaatgggcctagtgctttaacgatggtcaatggcggtcaggatttaacaaaaggttctactaactatgggaggctttctctcacacgcttagacgctaaaagcatcaatgtcgtttcggcttctgattcgcaacatttaggtttcacagcgattggttttggggaatctcaagtggcagaaaccacggtgaatttgcgcgatgttactgggaattttaacgctaatgtcaaatcagccagtggcgcgaactataacgccgtgatcgctagcggtaaccaaagcttgggatctggggttacaaccttaagagctgttgcaaatggtaaaaccacggatccgctgaaagcgctggacgatgctatcgcatctgtagacaaattccgttcttccctcggtgcggtgcaaaaccgtctggattccgcggttactaacctgaacaacaccactaccaacctgtctgaagcgcagtcccgtattcaggacgccgactatgcgaccgaagtgtccaatatgtcgaaagcgcagatcatccagcaggccggtaactccgtgttggcaaaagctaaccaggtaccgcagcaggttctgtctctgttacagggttactagagcgaggagaccaccaccaccaccaccactag
BBa_K133036_sequence
1
cgaggagaccaccaccaccaccaccactag
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z