BBa_K1333004
1
BBa_K1333004
M13 bacteriophage g5p with a FLAG tag on C-terminal
2014-09-23T11:00:00Z
2015-05-08T01:09:57Z
It is derived from the commercial M13KE vector(New England Biolabs) used in phage display system by PCR.
This part is coding the M13 bacteriophage g5p with a FLAG tag on C-terminal, which could act as an single strand DNA binding protein and RNA binding protein at the same time. These properties make g5p protein an important regulatory protein for M13 phage. In the life cycle of M13 phage, g5p protein would bind to newly synthesized viral genome ssDNA, resulting in the correct direction to the phage packaging site. Also, g5p protein would repress the expression of g2p protein by binding to the leader sequence of viral mRNA.
false
false
_1708_
0
18998
9
In stock
true
Between the g5p and FLAG coding sequencing, there are 9 nucleotides linker sequence coding a 3 amino acid peptide. It is not certain whether this peptide would affect the regular function of g5p protein.
false
Huang Junxiang, Wang Xizi
annotation2386062
1
g5p
range2386062
1
1
261
annotation2386063
1
FLAG
range2386063
1
271
297
BBa_K1333004_sequence
1
atgattaaagttgaaattaaaccatctcaagcccaatttactactcgttctggtgtttctcgtcagggcaagccttattcactgaatgagcagctttgttacgttgatttgggtaatgaatatccggttcttgtcaagattactcttgatgaaggtcagccagcctatgcgcctggtctgtacaccgttcatctgtcctctttcaaagttggtcagttcggttcccttatgattgaccgtctgcgcctcgttccggctaagagatcatcagactacaaagatgacgacgataaataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z