BBa_K1362090
1
T7 RBS
strong T7 RBS
2014-10-02T11:00:00Z
2015-05-08T01:10:04Z
synthesized as found in the T7 genome and several commercial expression plasmids.
RFC10 compatible strong RBS derived from the T7 phage gene 10a (major capsid protein)[1]. When assembled to a coding part with the A of the start codon being part of the XbaI site, the RBS will be shifted one bp downstream compared to the native sequence.
The sequence was successfully used by the iGEM team Heidelberg 2014 for the expression of many proteins in E.coli.
1. Olinss, P. & Rangwala, S. H. Derived from Bacteriophage T7 mRNA Acts ELS an Enhancer of Translation of the lac2 Gene in. 16973???16976 (1989).
false
false
_1738_
0
22830
9
It's complicated
false
The 18 bp including the XbaI that can be found upstream of the presumably important part of the RBS were included into the sequence just to make sure it works. However to fully comply with RFC10 a G was inserted behind the XbaI site.
false
Constantin Ahlmann-Eltze, Charlotte Bunne, Magdalena B??scher, Jan Gleixner, Max Horn, Anna Huhn, Nils Klughammer, Jakob Kreft, Elisabeth Sch??fer, Carolin Schmelas, Silvan Schmitz, Max Waldha
annotation2393795
1
t7 RBS
range2393795
1
11
28
annotation2393796
1
Shine-Dalgarno
range2393796
1
21
28
BBa_J70594
1
BBa_J70594
RFC12 TAATAA Tail Domain
2010-06-17T11:00:00Z
2015-05-08T01:08:25Z
Common Knowledge
A RFC12 compatible part that simply codes for two stop codons. This part does not have any degradation tag.
false
true
_41_
0
6384
41
Not in stock
false
Made with synthetic oligos:
5' AATTC GCGGCGC T ACTAGT TAATAA GCTAGC A GCGGCCG CTGCA 3'
5' GCGGCCGCTGCTAGC TTATTA ACTAGTAGCGCCGC G 3'
Note that both primers were ordered phosphorylated. An alternative is to phosphorylate the primers yourself with a kinase.
false
Joseph Lynch
annotation2071257
1
stop
range2071257
1
1
5
BBa_K1362470
1
BBa_K1362470
sfGFP_T65C sequence (Mutated <partinfo>BBa_I746917</partinfo>)
2014-10-08T11:00:00Z
2015-05-08T01:10:06Z
Comes from part: <partinfo>BBa_I746917</partinfo>
This is a mutated version of superfolder GFP <partinfo>BBa_I746917</partinfo> the T at position 65 has been mutated to a C. This mutation was inserted to serve as a control for the intein splicing reaction tested with the iGEM team Heidelberg 2014's split fluorescent protein assay.
false
false
_1738_
0
12377
9
Not in stock
false
This is only the raw sequence. Is was used in BBa_K1362170 which is a translational unit for mutated superfolder GFP.
false
Jakob Kreft
BBa_K1362170
1
sfGFP_T65C
Split sfGFP reconstitution positive control
2014-10-08T11:00:00Z
2015-05-08T01:10:05Z
???
???
false
false
_1738_
0
12377
9
In stock
false
???
false
Constantin Ahlmann-Eltze, Charlotte Bunne, Magdalena Buescher, Jan Gleixner, Max Horn, Anna Huhn, Nils Klughammer, Jakob Kreft, Elisabeth Schaefer, Carolin Schmelas, Silvan Schmitz, Max Waldhauer
component2414464
1
BBa_J70594
component2414456
1
BBa_K1362090
component2414457
1
BBa_G0000
component2414459
1
BBa_K371056
component2414460
1
BBa_K1362468
component2414462
1
BBa_K1362468
component2414461
1
BBa_K1362470
annotation2414459
1
BBa_K371056
range2414459
1
36
38
annotation2414456
1
BBa_K1362090
range2414456
1
1
29
annotation2414464
1
BBa_J70594
range2414464
1
786
791
annotation2414460
1
BBa_K1362468
range2414460
1
39
56
annotation2414462
1
BBa_K1362468
range2414462
1
768
785
annotation2414457
1
BBa_G0000
range2414457
1
30
35
annotation2414461
1
BBa_K1362470
range2414461
1
57
767
BBa_K1362468
1
BBa_K1362468
hexahistidine-tag
2014-10-08T11:00:00Z
2015-05-08T01:10:06Z
Sequence was assembled from the codon usage table http://www.genscript.com/cgi-bin/tools/codon_freq_table .
A Hexahistidine-tag for protein purification or detection on western blots.
false
false
_1738_
0
12377
9
Not in stock
false
none
false
Jakob Kreft
BBa_K371056
1
BBa_K371056
ATG
2010-11-05T12:00:00Z
2015-05-08T01:12:16Z
ATG
ATG
false
false
_498_
0
3908
9
Not in stock
false
ATG
false
Hao Jiang
annotation2113878
1
start codon
range2113878
1
1
3
BBa_G0000
1
scar
SpeI/XbaI scar for RBS-CDS junctions
2007-07-22T11:00:00Z
2015-08-31T04:07:27Z
SpeI/XbaI scar
This is the sequence of the SpeI/XbaI scar for RBS-CDS junctions in BioBricks standard assembly.
false
true
_41_
0
126
162
Not in stock
false
This is a shorter scar to ensure proper spacing between the RBS and CDS.
false
Reshma Shetty
BBa_K1362470_sequence
1
cgtaaaggcgaagagctgttcactggtgtcgtccctattctggtggaactggatggtgatgtcaacggtcataagttttccgtgcgtggcgagggtgaaggtgacgcaactaatggtaaactgacgctgaagttcatctgtactactggtaaactgccggtaccttggccgactctggtaacgacgctgtgttatggtgttcagtgctttgctcgttatccggaccatatgaagcagcatgacttcttcaagtccgccatgccggaaggctatgtgcaggaacgcacgatttcctttaaggatgacggcacgtacaaaacgcgtgcggaagtgaaatttgaaggcgataccctggtaaaccgcattgagctgaaaggcattgactttaaagaagacggcaatatcctgggccataagctggaatacaattttaacagccacaatgtttacatcaccgccgataaacaaaaaaatggcattaaagcgaattttaaaattcgccacaacgtggaggatggcagcgtgcagctggctgatcactaccagcaaaacactccaatcggtgatggtcctgttctgctgccagacaatcactatctgagcacgcaaagcgttctgtctaaagatccgaacgagaaacgcgatcatatggttctgctggagttcgtaaccgcagcgggcatcacgcatggtatggatgaactgtacaaa
BBa_J70594_sequence
1
taataa
BBa_K1362170_sequence
1
aataattttgtttaactttaagaaggagatactagatgcaccaccaccaccaccaccgtaaaggcgaagagctgttcactggtgtcgtccctattctggtggaactggatggtgatgtcaacggtcataagttttccgtgcgtggcgagggtgaaggtgacgcaactaatggtaaactgacgctgaagttcatctgtactactggtaaactgccggtaccttggccgactctggtaacgacgctgtgttatggtgttcagtgctttgctcgttatccggaccatatgaagcagcatgacttcttcaagtccgccatgccggaaggctatgtgcaggaacgcacgatttcctttaaggatgacggcacgtacaaaacgcgtgcggaagtgaaatttgaaggcgataccctggtaaaccgcattgagctgaaaggcattgactttaaagaagacggcaatatcctgggccataagctggaatacaattttaacagccacaatgtttacatcaccgccgataaacaaaaaaatggcattaaagcgaattttaaaattcgccacaacgtggaggatggcagcgtgcagctggctgatcactaccagcaaaacactccaatcggtgatggtcctgttctgctgccagacaatcactatctgagcacgcaaagcgttctgtctaaagatccgaacgagaaacgcgatcatatggttctgctggagttcgtaaccgcagcgggcatcacgcatggtatggatgaactgtacaaacaccaccaccaccaccactaataa
BBa_G0000_sequence
1
tactag
BBa_K1362090_sequence
1
aataattttgtttaactttaagaaggaga
BBa_K371056_sequence
1
atg
BBa_K1362468_sequence
1
caccaccaccaccaccac
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z