BBa_K1366101
1
BBa_K1366101
Genetic construct for lpp gene deletion (C1)
2014-10-09T11:00:00Z
2015-05-08T01:10:07Z
The genetic design is based in the lpp deletion done by:
Ni, Y., Reyes, J., & Chen, R. (2007). lpp Deletion as a Permeabilization Method. Biotechnology and Bioengineering, 1347-1356.
It also contains some parts of the registry like BBa_K1073000, BBa_B0034, BBa_B0015
This biobrick contains the sequence homologies (50bp) to delete lpp gen (LPS moiety carrier) in E. coli with an ampicillin resistance and a Multiple Cloning Site (for the generation of genomic knock-ins of any desired gen in E. coli). The deletion of lpp gene and the replacement of that sequence with the Amp resistance. Gene deletions are performed with lambda-red recombination technology. FLP-FRT sequences are included to remove the antibiotic resistance with a specific recombinase.
false
false
_1743_
0
16722
9
It's complicated
false
This is the general structure
50bp homology Lpp // FRT // Amp R Promoter // RBS // AmpR // Terminator // FRT // MCS // 50 bp homology Lpp
false
Eduardo Cepeda Ca??edo, Mercedes Alejandra Vazquez Cantu
annotation2427291
1
FRT
range2427291
1
1200
1234
annotation2427287
1
BBa_B0034
range2427287
1
157
169
annotation2427285
1
FRT
range2427285
1
51
84
annotation2427290
1
MCS
range2427290
1
1164
1199
annotation2427289
1
BBa_B0015
range2427289
1
1035
1163
annotation2427288
1
AmpR
range2427288
1
170
1034
annotation2427284
1
50 bp lpp homology (1)
range2427284
1
1
50
annotation2427292
1
50 bp lpp homology (2)
range2427292
1
1235
1285
annotation2427286
1
AmpR promoter
range2427286
1
86
156
BBa_K1366101_sequence
1
agctttgtgtaatacttgtaacgctacatggagattaactcaatctagaggggaagttcctatactttttagagaataggaacttcttcaaatatgtatccgctcatgagacaataaccctgataaatgcttcaataatattgaaaaaggaagagtaaagaggagaaaatgagtattcaacatttccgtgtcgcccttattcccttttttgcggcattttgccttcctgtttttgctcacccagaaacgctggtgaaagtaaaagatgccgaagatcagttgggtgcacgtgtgggttacatcgaactggacctcaacagcggtaagattcttgagagttttcgccccgaagaacgtttcccaatgatgagcacttttaaagttctgctctgtggcgcggtattatcccgtattgacgccgggcaagagcaactcggtcgccgcatacactattctcagaatgacttggttgagtactcaccagtcacagaaaagcatcttacggacggcatgacagtacgcgaattatgcagcgctgccataaccatgagtgataacacggcggccaacttacttctgacaacgatcggaggaccgaaggagcttaccgcttttttgcacaacatgggtgatcatgtaactcgccttgatcgttgggaaccggagctgaatgaagccataccaaacgacgagcgtgacaccacgatgcctgtagctatggcaacaacgttgcgcaaactcttaactggcgaacttcttactctcgcttcccggcaacaattaatagactggatggaggcggataaagttgcaggaccacttctgcgctcggcccttccggctggctggtttattgctgataaatctggagccggtgagcgtgggtcccgcggtattattgcagccctggggccagatggtaagccctcccgtatcgtagttatctacacgacggggagccaggcaactatggacgaacgtaatcgccagatcgctgagataggtgcctccctgattaagcattggtaataaccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttatagaagttcctatactttttagagaataggaacttcaagcttggatccgtcgacggtacccacattgtgcgccattttttttgtctgccgtttaccgctactgcgtcacg
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z