BBa_K1382000 1 BBa_K1382000 Melittin 2014-06-16T11:00:00Z 2015-05-08T01:10:13Z Apis mellifera (Honeybee) Melittin is an antimicrobial peptide which has strong hemolytic activity. It is a toxin which makes up 50-70% of bee venom. Melittin functions by inserting itself into lipid bilayers,creating pores which allow for the movement of ions. This ion exchange, especially of Ca2+, can also help to activate phospholipase A2 in the outer membrane of a cell. At higher concentrations, melittin forms larger pores that allow for the transport of molecules and which destabilize the cell membrane, eventually causing cell lysis. false false _1759_ 0 20570 9 It's complicated false We considered optimization for the expression of melittin within Escherichia coli false Helen Liu, Gregory Poterewicz BBa_K1382000_sequence 1 atgggaattggagcagttctgaaggtattaaccacaggattgcccgccctcataagttggattaaacgtaagaggcaacagggttaataa igem2sbol 1 iGEM to SBOL conversion Conversion of the iGEM parts registry to SBOL2.1 Chris J. Myers James Alastair McLaughlin 2017-03-06T15:00:00.000Z