BBa_K1439004
1
BBa_K1439004
TAT-H4
2014-10-04T11:00:00Z
2015-05-08T01:10:26Z
Histone H4 comes from the Wheat histone H4 gene, and TAT-PTD comes from HIV-1's TAT protein gene.
Histone H4 can efficiently mediate gene transfer, it rich in positively charged alkaline amino acids and has the ability to combine with DNA. TAT-PTD contains an 11-amino acid peptide, and these amino acids YGRKKRRQRRR are highly basic, which is crucial for penetrating the plasma membrane. We use linker to link H4 histone and TAT, thus it can seize DNA and take it into cells. Now, it becomes our transfer device.
false
false
_1817_
0
21804
9
It's complicated
false
We found the sequence from NCBI, and synthetized primer.
false
Zhaoliang Chen
annotation2394213
1
misc
range2394213
1
1
393
BBa_K1439004_sequence
1
atgtatggtcgtaaaaaacgtcgtcagcgtcgtcgcggtggaggaggctctggtggaggcggtagcggaggcggagggtcgatgtccgggcgcggcaagggaggcaagggcctaggcaagggcggcgccaagcgccaccggaaggtcctccgcgataacatccagggcatcaccaagccggcgatccggcggctggcgcggcggggcggcgtgaagcgcatctcggggctcatctacgaggagacccgcggcgtgctcaagatcttcctcgagaacgtcatccgcgatgccgtcacctacaccgagcacgcccgccgcaagaccgtcaccgccatggacgtcgtctacgcgctcaagcgccagggccgcaccctctacggcttcggcggctaa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z