BBa_K1459006
1
BBa_K1459006
pmrC
2014-10-06T11:00:00Z
2015-05-08T01:10:32Z
We obtained the pmrC-GFP sequence thanks to kindness of prof. He from University of Chicago.
This is pmrC promoter native to Salmonella enterica.
PmrA-PmrB two-component system is native to Salmonella enterica and in it's native state it is responsible for chemotaxis. PmrB is a transmembrane protein with iron binding peptide on it's extracellular loop. When PmrB binds iron (III) iron, it's intracellular domain gains kinase activity and phosphorylates PmrA, which subsequently binds to pmrC promoter and induces expression of chemotaxis CheZ protein. In this part iron binding tag on the extracellular loop was exchanged with a lanthanide binding tag (LBT), to allow PmrA-PmrB two-component system to respond to lanthanide ions.
false
false
_1837_
0
20803
9
Not in stock
false
This is pmrC sequence derived from bioinformatic sources, after search for promotor at 5' end of CheZ protein.
false
Grzegorz Ścibisz
BBa_K1459006_sequence
1
tcaccctggtgccttatctttacacctgtgcggcgttactgctgctcggacacggtcactttggtaaagcacgcccggcatatctggcagttactaccattgccttcctctactgcatctgggccgtggtggggtccggagcgaaagaggttatgtggtcatttgtcaccctgatggtcatcaccgccatgtatgcgctgaattacaaccggctacataaaaacccgtatcccttagatgcaccaataagcaaagattaattccccttaatccagcaaacataaaagccaaccttaagaacttaaggttggcttaattttgctttgcgagcatatgcgcactttgttcgatggaaacaccgtggtacccggggatcctctataattaaagaggagaaattaagc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z