BBa_K1510007
1
BBa_K1510007
sRNA targets G protein mRNA in S.mutans
2014-10-05T11:00:00Z
2015-05-08T01:10:47Z
constitutive promoter(veg promoter) is came from Bacillus subtilis, and MicC scaffold is came from E.coli k-12 MG1655.
Other parts are synthesized by primer.
veg promoter(constitutive promoter in S.mutans+ G protein sRNA+ MicC scaffold+ terminator. Constitutive promoter(veg promoter) is came from Bacillus subtilis, and MicC scaffold is came from E.coli k-12 MG1655.Other parts are synthesized by primer.
This part will transcibe into sRNA, and sRNA will bind to mRNA of SGP(S.mutans G protein), prevent SGP mRNA from translating. Because G protein is a biofilm formation-related protein, this part is created to decrease biofilm formation.
false
false
_1890_
0
21299
9
In stock
false
Because we need to put our part into vector PVA838 to shuttle plasmid between E.coli and S.mutans. The restriction site before part is EcoRI and BamHI in the last. In addition, to achieve best efficiency, we also consider the spacer between promoter and coding sequence without RBS(because our final product is RNA)
false
Wei-Tai Chen
annotation2396884
1
sRNA targets G protein
range2396884
1
42
65
annotation2396887
1
terminator
range2396887
1
145
157
annotation2396886
1
MicC scaffold
range2396886
1
66
144
annotation2396882
1
Veg promoter
range2396882
1
1
36
BBa_K1510007_sequence
1
ttgacaaaaatgggctcgtgttgtacaataaatgtaatgcaagcggttaaaattaaagtccacattttctgttgggccattgcattgccactgattttccaacatataaaaagacaagcccgaacagtcgtccgggctttttttcagctgatagctg
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z