BBa_K1510409
1
BBa_K1510409
A Steptococcus Mutants adhesive complex.
2014-10-06T11:00:00Z
2015-05-08T01:10:48Z
We truncate K523013 of 2011 Edinberg team and derive C16 from the genome of Streptococuus Mutants UA159.
A fusion of truncated INPNC anchor protein and C16 Streptococcus Mutants signal peptide becomes a bridge between E.coli and Streptococcus Mutants. This double-unit complex may not only provide a higher targeting specificity but also allow us to improve several cell-cell interactions, such as biofilm degrading and cell-holing. And in our cases, the cell-cell binding between our E.coli and Streptococcus Mutants may help us co-culture into the pathogenic-biofilm. The biofilm has long been accused of the most troublesome concrete barrier to surpass in organisms. The physical feature of biofilm often nests several pathogens, and its polysaccharide structure may serve as a safe shelter, preventing us from ridding problems from the root. However, we are flipping the game this time. With the aid of K1510816, our E.coli can attach on the Streptococcus Mutants, and be co-cultured into biofilm, giving us the chance to challenge the unsolved oral-biofilm problem.
false
false
_1890_
0
21271
9
It's complicated
false
Make sure the tail linker of INPNC sequence can match the C16 prefix.
false
Kao Jung Chang
annotation2404176
1
INPNC
range2404176
1
632
1555
annotation2404175
1
rbs
range2404175
1
611
613
annotation2404177
1
C16
range2404177
1
1601
1651
annotation2404174
1
plac+lacz
range2404174
1
38
581
annotation2404178
1
BBa_B0015
range2404178
1
1652
1780
BBa_K1510409_sequence
1
ttaatacgactcactatagggagaggaggtacgatctgctggggcaaaccagcgtggaccgcttgctgcaactctctcagggccaggcggtgaagggcaatcagctgttgcccgtctcactggtgaaaagaaaaaccaccctggcgcccaatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtgagcgcaacgcaattaatgtgagttagctcactcattaggcaccccaggctttacactttatgcttccggctcgtatgttgtgtgaaattgtgagcggataacaatttcacacaggaaacagctatgaccatgattacggattcactggccgtcgttttacaacgtcgtgactgggaaaaccctggcgttacccaacttaatcgccttgcagcacatccccctttcgccagctggcgtaatagcgaagaggcccgcaccgatcgcccttcccaacagttgcgcagcctgaatggcgaatggcgctttgcctggtttccggcaccagaagcggtgccggaaagctggctggagtgatactagctgatatttcgcgtaaggaaatccattatgggatctatgaccctggataaagcgctggtgctgcgcacttgtgccaataatatggccgaccattgtggcctgatctggcctgcttctggtacagttgaaagccgctattggcagtctacacgtcgtcacgaaaacgggctggttgggctgctgtggggtgccggaacatccgcctttctgagcgttcatgccgatgctcgttggattgtttgtgaggttgctgttgccgacatcattagcctggaagaaccgggtatggtgaaatttcctcgtgctgaagtggtccatgttggtgatcgtattagcgcctcccatttcatttcagctcgtcaggctgatccagcaagcacatcaacaagcacctctaccagtacactgacaccaatgccaaccgctatccctactcctatgccggctgtagcctctgttactctgcctgtggccgaacaagctcgccacgaagtctttgacgttgcctctgtgtctgctgctgctgctcctgttaacactctgcctgttaccacgcctcaaaatctgcaaacggcgacctatggctcaacactgagtggtgataaccattctcgtctgattgccgggtatggctctaacgaaaccgccggaaaccattctgatctgatcggtggtcacgattgtacgctgatggcaggtgatcaatctcgtctgaccgctggcaaaaattccgttctgaccgctggggcacgttctaaactgatcgggagcgaaggctctactctgtccgccggagaagattctaccctgatctttcgtctgtgggatggtaaacgttatcgtcagctggtcgctcgtacaggtgaaaatggtgtggaagccgacattccgtattatgtgaatgaggacgatgatattgtggacaaaccggacgaagatgatgattggatcgaagtgaaaggtactagcagcagcattgcgagcagcagcccgagcagcgtggcgacatttttccggctgtttaacagaagttttacacaagctttgggaaaataaccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z