BBa_K156021
1
BBa_K156021
Promoter + RBS + phaA + double terminator
2008-10-28T12:00:00Z
2015-05-08T01:10:54Z
This is a composite part.
This device is a synthetic gene that generates PhaA, an enzyme that catalyzes the synthesis of acetoacetyl-coenzyme A from two molecules of acetyl-coenzyme A. The enzyme can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation.
false
false
_246_
0
1475
9
It's complicated
false
No special design considerations.
false
George McArthur IV
component1993806
1
BBa_B0012
component1993803
1
BBa_K156012
component1993801
1
BBa_B0032
component1993795
1
BBa_R0040
component1993804
1
BBa_B0010
annotation1993804
1
BBa_B0010
range1993804
1
1272
1351
annotation1993801
1
BBa_B0032
range1993801
1
63
75
annotation1993795
1
BBa_R0040
range1993795
1
1
54
annotation1993806
1
BBa_B0012
range1993806
1
1360
1400
annotation1993803
1
BBa_K156012
range1993803
1
82
1263
BBa_B0032
1
BBa_B0032
RBS.3 (medium) -- derivative of BBa_0030
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
Weak1 RBS based on Ron Weiss thesis. Strength is considered relative to <bb_part>BBa_B0030</bb_part>, <bb_part>BBa_B0031</bb_part>, <bb_part>BBa_B0033</bb_part>.
false
true
_41_44_48_46_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix ("RBS-2" in figure 4-14 of thesis). <P>
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation1709
1
RBS-3\Weak
range1709
1
1
13
annotation7027
1
BBa_B0032
range7027
1
1
13
annotation1710
1
RBS
range1710
1
7
10
BBa_K156012
1
Bioplastic
phaA (acetyl-CoA acetyltransferase)
2008-10-28T12:00:00Z
2015-05-08T01:10:54Z
This coding region is native to ''Ralstonia eutropha'' H16. The original sequence was obtained from GenBank (VERSION NC_008313.1, GI:113866031).
This part codes for an enzyme that catalyzes the synthesis of acetoacetyl-coenzyme A from two molecules of acetyl-coenzyme A. The enzyme can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation.
false
false
_246_
0
1475
9
It's complicated
false
This part was codon-optimized for expression in E. coli. The following restriction enzyme sites were also removed: EcoRI, NotI, XbaI, SpeI, PstI, NheI, AvrII, ApoI, MfeI, NsiI, SbfI.
false
George McArthur IV
BBa_B0010
1
BBa_B0010
T1 from E. coli rrnB
2003-11-19T12:00:00Z
2015-08-31T04:07:20Z
Transcriptional terminator consisting of a 64 bp stem-loop.
false
false
_1_
0
24
7
In stock
false
true
Randy Rettberg
annotation7018
1
BBa_B0010
range7018
1
1
80
annotation4184
1
stem_loop
range4184
1
12
55
BBa_B0012
1
BBa_B0012
TE from coliphageT7
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Derived from the TE terminator of T7 bacteriophage between Genes 1.3 and 1.4 <genbank>V01146</genbank>.
Released HQ 2013
Transcription terminator for the <i>E.coli</i> RNA polymerase.
false
false
_1_
0
24
7
In stock
false
<P> <P>Suggested by Sri Kosuri and Drew Endy as a high efficiency terminator. The 5' end cutoff was placed immediately after the TAA stop codon and the 3' end cutoff was placed just prior to the RBS of Gene 1.4 (before AAGGAG).<P> Use anywhere transcription should be stopped when the gene of interest is upstream of this terminator.
false
Reshma Shetty
annotation1687
1
stop
range1687
1
34
34
annotation1690
1
polya
range1690
1
28
41
annotation1686
1
T7 TE
range1686
1
8
27
annotation7020
1
BBa_B0012
range7020
1
1
41
BBa_R0040
1
p(tetR)
TetR repressible promoter
2003-01-31T12:00:00Z
2015-05-08T01:14:14Z
Lutz, R., Bujard, H., <em>Nucleic Acids Research</em> (1997) 25, 1203-1210.
Released HQ 2013
Sequence for pTet inverting regulator driven by the TetR protein.</P>
false
true
_1_
0
24
7
In stock
false
<P> <P>BBa_R0040 TetR-Regulated Promoter is based on a cI promoter. It has been modified to include two TetR binding sites and the BioBrick standard assembly head and tail restriction sites.<P>
true
June Rhee, Connie Tao, Ty Thomson, Louis Waldman
annotation1986784
1
BBa_R0040
range1986784
1
1
54
annotation1986785
1
-35
range1986785
1
20
25
annotation1986783
1
TetR 1
range1986783
1
1
19
annotation1986787
1
-10
range1986787
1
43
48
annotation1986786
1
TetR 2
range1986786
1
26
44
BBa_B0010_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctc
BBa_R0040_sequence
1
tccctatcagtgatagagattgacatccctatcagtgatagagatactgagcac
BBa_B0032_sequence
1
tcacacaggaaag
BBa_B0012_sequence
1
tcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_K156012_sequence
1
atgactgatgttgttattgtatctgccgctcgtactgctgttggtaaatttggtggtagcctggctaaaatcccggcacctgagctgggcgctgtagttatcaaagctgcgctggaacgtgcgggcgttaaaccggagcaagtgtccgaagtcatcatgggccaagtactgacggcgggcagcggccagaacccggctcgccaggcggccattaaagcaggtctgccggccatggtgccggcaatgaccattaacaaagtttgcggttctggtctgaaagctgttatgctggcagctaatgcaatcatggcaggtgacgcagagattgttgtcgctggtggtcaagaaaacatgagcgctgctccgcatgttctgccaggctcccgtgacggtttccgtatgggtgatgcaaaactggtggacactatgatcgtcgacggcctgtgggatgtgtataaccagtatcacatgggtattaccgcagagaacgttgcgaaagaatatggcattacgcgtgaagcgcaggacgaatttgcagtgggttctcagaacaaagccgaagcggctcagaaagctggtaagttcgacgaagaaatcgtaccggttctgattccgcagcgcaagggtgatccggtagcattcaaaaccgatgagttcgtacgccagggcgctactctggattccatgtctggcctgaaaccggcattcgacaaagcaggtaccgtgacggctgcgaacgcgagcggcctgaacgatggcgcggctgcggttgtggtcatgagcgcggcgaaagctaaagaactgggcctgacgccgctggcgactatcaaatcttacgcgaacgcaggtgtggatccgaaggtgatgggtatgggtcctgtgccagctagcaagcgcgctctgtcccgcgctgaatggactccgcaggatctggatctgatggagattaacgaagctttcgctgcgcaggcgctggcggtacatcagcagatgggttgggacacttctaaagtcaatgtaaacggcggtgccattgcgatcggccacccgatcggcgcttccggttgccgcatcctggtaaccctgctgcacgaaatgaaacgtcgtgacgctaagaaaggtctggcctctctgtgcattggtggcggcatgggtgttgccctggccgttgaacgtaaatga
BBa_K156021_sequence
1
tccctatcagtgatagagattgacatccctatcagtgatagagatactgagcactactagagtcacacaggaaagtactagatgactgatgttgttattgtatctgccgctcgtactgctgttggtaaatttggtggtagcctggctaaaatcccggcacctgagctgggcgctgtagttatcaaagctgcgctggaacgtgcgggcgttaaaccggagcaagtgtccgaagtcatcatgggccaagtactgacggcgggcagcggccagaacccggctcgccaggcggccattaaagcaggtctgccggccatggtgccggcaatgaccattaacaaagtttgcggttctggtctgaaagctgttatgctggcagctaatgcaatcatggcaggtgacgcagagattgttgtcgctggtggtcaagaaaacatgagcgctgctccgcatgttctgccaggctcccgtgacggtttccgtatgggtgatgcaaaactggtggacactatgatcgtcgacggcctgtgggatgtgtataaccagtatcacatgggtattaccgcagagaacgttgcgaaagaatatggcattacgcgtgaagcgcaggacgaatttgcagtgggttctcagaacaaagccgaagcggctcagaaagctggtaagttcgacgaagaaatcgtaccggttctgattccgcagcgcaagggtgatccggtagcattcaaaaccgatgagttcgtacgccagggcgctactctggattccatgtctggcctgaaaccggcattcgacaaagcaggtaccgtgacggctgcgaacgcgagcggcctgaacgatggcgcggctgcggttgtggtcatgagcgcggcgaaagctaaagaactgggcctgacgccgctggcgactatcaaatcttacgcgaacgcaggtgtggatccgaaggtgatgggtatgggtcctgtgccagctagcaagcgcgctctgtcccgcgctgaatggactccgcaggatctggatctgatggagattaacgaagctttcgctgcgcaggcgctggcggtacatcagcagatgggttgggacacttctaaagtcaatgtaaacggcggtgccattgcgatcggccacccgatcggcgcttccggttgccgcatcctggtaaccctgctgcacgaaatgaaacgtcgtgacgctaagaaaggtctggcctctctgtgcattggtggcggcatgggtgttgccctggccgttgaacgtaaatgatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z