BBa_K1583000
1
BBa_K1583000
CsgA
2015-09-01T11:00:00Z
2015-09-02T09:46:13Z
The DNA was synthesized. The sequence originates from the genomic DNA of E. coli K-12 MG1655 (http://www.ncbi.nlm.nih.gov/gene/949055).
This gene encodes for the protein CsgA. CsgA is a curlin subunit that can self-assemble into curli after nucleation on CsgB. They are produced in an unpolymerized form and secreted from the cell.
CsgA is naturally produced by e.g. E. coli K-12 MG1655 from the operon CsgBA. A second operon, CsgDEFG encodes four additional proteins that are required for the curli assembly and secretion.
false
false
_2000_
24478
24478
9
false
The nucleotides encoding for the third and fourth amino acids of the gene are changed to improve the success change of synthesis
false
Max van 't Hof
annotation2442926
1
CsgA
range2442926
1
1
456
BBa_G0002
1
SX scar
SpeI/XbaI mixed site
2007-02-26T12:00:00Z
2015-08-31T04:07:27Z
XbaI and SpeI sites
XbaI/SpeI mixed site. Simply used to aid in entry of parts into the registry.
false
true
_41_
0
126
70
Not in stock
false
None.
false
Reshma Shetty
BBa_K1583051
1
BBa_K1583051
Scar 2
2015-09-03T11:00:00Z
2015-09-18T07:34:25Z
This scar is part of a synthesized construct.
Scar in constructs BBa_K1583100 - BBa_K1583112
false
false
_2000_
24478
24478
9
false
This scar originates from the part BBa_K1316015, on which the composite part BBa_K1583100 is based.
false
Max van 't Hof
annotation2475065
1
Scar
range2475065
1
1
14
BBa_K1583100
1
BBa_K1583100
pRha + CsgA
2015-09-02T11:00:00Z
2015-09-18T11:09:29Z
This part was synthesized. The rhamnose promoter was used by the iGEM 2014 TU Delft teama and originally added by the iGEM12 Paris Bettencourt team. RBS and CsgA originate from E. coli K-12 MG1655
CsgA under control of L-rhamnose-inducible promoter
false
false
_2000_
24478
24478
9
false
The nucleotides encoding for the second and third amino acid of the CsgA gene were changed to optimize synthesis success. (silent mutations)
false
Max van 't Hof
component2443485
1
BBa_K914003
component2443489
1
BBa_K1583000
component2443486
1
BBa_K1583050
component2443490
1
BBa_K1583051
component2443487
1
BBa_K1583008
component2443483
1
BBa_G0002
annotation2443490
1
BBa_K1583051
range2443490
1
625
638
annotation2443487
1
BBa_K1583008
range2443487
1
156
167
annotation2443486
1
BBa_K1583050
range2443486
1
131
155
annotation2443485
1
BBa_K914003
range2443485
1
9
130
annotation2443483
1
BBa_G0002
range2443483
1
1
8
annotation2443489
1
BBa_K1583000
range2443489
1
169
624
BBa_K914003
1
BBa_K914003
L-rhamnose-inducible promoter (pRha)
2012-09-19T11:00:00Z
2015-05-08T01:13:45Z
Amplification of the plasmid pJOE3075 (Dr. Altenbuchner).
Released HQ 2013
L-rhamnose-inducible promoter is capable of high-level recombinant protein expression in the presence of L-rhamnose, it is also tightly regulated in the absence of L-rhamnose by the addition of D-glucose.
false
false
_1179_
0
13487
9
In stock
true
One base pair modified (90: A -> T) to avoid EcoRI site. Mutation made in a less conserved base pair.
false
Denis Samuylov
annotation2188559
1
pRha
range2188559
1
1
122
BBa_K1583008
1
BBa_K1583008
RBS
2015-09-03T11:00:00Z
2015-09-04T05:18:43Z
Synthesized
RBS
false
false
_2000_
24478
24478
9
false
Based on RBS of BBa_K1316015.
false
Max van
BBa_K1583050
1
BBa_K1583050
Scar 1
2015-09-03T11:00:00Z
2015-09-18T07:33:29Z
This scar is part of a synthesized construct.
Scar in constructs BBa_K1583100 - BBa_K1583112
false
false
_2000_
24478
24478
9
false
This scar originates from the part BBa_K1316015, on which the composite part BBa_K1583100 is based.
false
Max van 't Hof
annotation2475064
1
Scar
range2475064
1
1
25
BBa_K1583051_sequence
1
ctactagaaggagg
BBa_K1583000_sequence
1
atgaaactgctgaaagtagcagcaattgcagcaatcgtattctccggtagcgctctggcaggtgttgttcctcagtacggcggcggcggtaaccacggtggtggcggtaataatagcggcccaaattctgagctgaacatttaccagtacggtggcggtaactctgcacttgctctgcaaactgatgcccgtaactctgacttgactattacccagcatggcggcggtaatggtgcagatgttggtcagggctcagatgacagctcaatcgatctgacccaacgtggcttcggtaacagcgctactcttgatcagtggaacggcaaaaattctgaaatgacggttaaacagttcggtggtggcaacggtgcagcagttgaccagactgcatctaactcctccgtcaacgtgactcaggttggctttggtaacaacgcgaccgctcatcagtactaa
BBa_K1583100_sequence
1
tactagagccacaattcagcaaattgtgaacatcatcacgttcatctttccctggttgccaatggcccattttcctgtcagtaacgagaaggtcgcgtattcaggcgctttttagactggtcgtaatgaatactagagcagcaaggaaatactagaaggaggtatataatgaaactgctgaaagtagcagcaattgcagcaatcgtattctccggtagcgctctggcaggtgttgttcctcagtacggcggcggcggtaaccacggtggtggcggtaataatagcggcccaaattctgagctgaacatttaccagtacggtggcggtaactctgcacttgctctgcaaactgatgcccgtaactctgacttgactattacccagcatggcggcggtaatggtgcagatgttggtcagggctcagatgacagctcaatcgatctgacccaacgtggcttcggtaacagcgctactcttgatcagtggaacggcaaaaattctgaaatgacggttaaacagttcggtggtggcaacggtgcagcagttgaccagactgcatctaactcctccgtcaacgtgactcaggttggctttggtaacaacgcgaccgctcatcagtactaactactagaaggagg
BBa_K1583050_sequence
1
tactagagcagcaaggaaatactag
BBa_K1583008_sequence
1
aaggaggtatat
BBa_G0002_sequence
1
tactagag
BBa_K914003_sequence
1
ccacaattcagcaaattgtgaacatcatcacgttcatctttccctggttgccaatggcccattttcctgtcagtaacgagaaggtcgcgtattcaggcgctttttagactggtcgtaatgaa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z