BBa_K1607011 1 BBa_K1607011 The SCFV of anti-p185her2/neu antibody chA21 linked with EGFP by a (Gly4Ser)3 linker 2015-08-25T11:00:00Z 2015-08-26T08:57:56Z LCR assembly and PCR.(detailed description will be provided soon) The anti-p185her2/neu antibody chA21 mediates specific inhibitory effects on p185her2/neu-overexpressed cancer cells, as well as human breast and ovarian cancer xenograft [1] This part is the coding sequence of chA21 SCFV, fused with EGFP.A (Gly4Ser)3 linker was inserted. The SCFV should be able to specifically bind to tumor antigen p185her2/neu-ECD (???ECD??? stands for ???extracellular domain???). false false _2024_ 25365 25365 9 false design information will be provided soon false Jiazheng Xing annotation2438124 1 chA21SCFV range2438124 1 1 585 annotation2438126 1 EGFP range2438126 1 631 1347 annotation2438125 1 (Gly4Ser)3 linker range2438125 1 586 630 BBa_K1607011_sequence 1 atgggttctactcaagtttgtactggtactgatatgaagttgagattgccagcttctccagaaactcatttggatatgttgagacatttgtaccaaggttgtcaagttgttcaaggtaacttggaattgacttacttgccaactaacgcttctttgtcttttttgcaagatattcaagaagttcaaggttacgttttgattgctcataaccaagttagacaagttccattgcaaagattgagaattgttagaggtactcaattgtttgaagataactacgctttggctgttttggataacggtgatccattgaacaacactactccagttactggtgcttctccaggtggtttgagagaattgcaattgagatctttgactgaaattttgaagggtggtgttttgattcaaagaaacccacaattgtgttaccaagatactattttgtggaaggatatttttcataagaacaaccaattggctttgactttgattgatactaacagatccagagcttgtcatccatgttctccaatgtgtaagggttccagatgttggggtgaatcttctgaagattgtcaatctggcggtggcggttctggaggcggaggcagcggtggcggtggaagcatggtgagcaagggcgaggagctgttcaccggggtggtgcccatcctggtcgagctggacggcgacgtaaacggccacaagttcagcgtgtccggcgagggcgagggcgatgccacctacggcaagctgaccctgaagttcatctgcaccaccggcaagctgcccgtgccctggcccaccctcgtgaccaccctgacctacggcgtgcagtgcttcagccgctaccccgaccacatgaagcagcacgacttcttcaagtccgccatgcccgaaggctacgtccaggagcgcaccatcttcttcaaggacgacggcaactacaagacccgcgccgaggtgaagttcgagggcgacaccctggtgaaccgcatcgagctgaagggcatcgacttcaaggaggacggcaacatcctggggcacaagctggagtacaactacaacagccacaacgtctatatcatggccgacaagcagaagaacggcatcaaggtgaacttcaagatccgccacaacatcgaggacggcagcgtgcagctcgccgaccactaccagcagaacacccccatcggcgacggccccgtgctgctgcccgacaaccactacctgagcacccagtccgccctgagcaaagaccccaacgagaagcgcgatcacatggtcctgctggagttcgtgaccgccgccgggatcactctcggcatggacgagctgtacaag igem2sbol 1 iGEM to SBOL conversion Conversion of the iGEM parts registry to SBOL2.1 Chris J. Myers James Alastair McLaughlin 2017-03-06T15:00:00.000Z