BBa_R0011
1
lacI+pL
Promoter (lacI regulated, lambda pL hybrid)
2003-01-31T12:00:00Z
2015-05-08T01:14:14Z
represillator of Elowitz and Leibler (2000)
Released HQ 2013
Inverting regulatory region controlled by LacI (<bb_part>BBa_C0010</bb_part>, <bb_part>BBa_C0011</bb_part>, etc.) <p> The PLlac 0-1 promoter is a hybrid regulatory region consisting of the promoter P(L) of phage lambda with the cI binding sites replaced with lacO1. The hybrid design allows for strong promotion that can nevertheless be tightly repressed by LacI, the Lac inhibitor (i.e. repressor) (<bb_part>BBa_C0010</bb_part>) ([LUTZ97]). The activity of the promoter can be regulated over a >600-fold range by IPTG in E.Coli DH5-alpha-Z1 (same paper reference).
false
true
_1_
0
24
7
In stock
false
<P> <P>hybrid promoter design to create strong promoter that is, at the same time, highly repressible. note that the upstream operator installed in this hybrid is slightly different than the one in the original source (Lutz and Bujard, 1997). the most upstream operator region is slightly truncated in the represillator version, so that both operators in the hybrid are the same sequence. see references for details. also, the sequence has been truncated after the transcriptional start site.<P>LacI binds to this regulator. This part is incompatible with species containing active LacI coding regions. Lactose and IPTG disable the operation of LacI and increase transcription. This part is incompatible with environments containing lactose or lactose analogs.
true
Neelaksh Varshney, Grace Kenney, Daniel Shen, Samantha Sutton
annotation2002
1
-10
range2002
1
43
48
annotation7064
1
BBa_R0011
range7064
1
1
54
annotation2001
1
lac O1
range2001
1
26
42
annotation1999
1
lac O1
range1999
1
3
19
annotation2000
1
-35
range2000
1
20
25
BBa_K314111
1
BBa_K314111
Lac I
2010-10-07T11:00:00Z
2015-05-08T01:11:55Z
Pet 29 vector
Lac I gene with promoter and RBS
false
false
_496_
0
6395
9
It's complicated
false
false
IGEM 2010 Team Washington
BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_K314110
1
f1 ori
f1 origin
2010-10-07T11:00:00Z
2015-05-08T01:11:55Z
Pet 29 vector
Released HQ 2013
Phage origin recognized by M13. Used to make SS DNA when infected with M13k07 helper phage
false
false
_496_
0
6395
9
In stock
true
false
IGEM 2010 Team Washington
annotation2115768
1
f1 origin
range2115768
1
18
324
BBa_K1615067
1
TVEL5
Laccase TVEL5 in RFC25
2015-08-27T11:00:00Z
2015-08-28T09:30:45Z
Laccase from Tramates versicolor.
Laccase TVEL5 from Tramates versicolor.
false
false
_2032_
25547
25547
9
false
Codon optimised for E. coli. RFC 25 compatible.
false
Brooke Rothschild-Mancinelli
BBa_K1615068
1
BBa_K1615068
TVEL5 driven by LacI promoter
2015-09-01T11:00:00Z
2015-09-02T04:06:06Z
TVEL5 Laccase from Tramates versicolor. Lac expression cassette from iGEM10_Washington.
TVEL5 Laccase under the control of a Lac inducible promoter.
false
false
_2032_
25547
25547
9
false
Fusion was performed using RFC10 standard due to illegal NgoMIV site in f1 origin.
false
Brooke Rothschild-Mancinelli
component2442864
1
BBa_K1615067
component2442861
1
BBa_K314103
component2442863
1
BBa_K1319106
annotation2442863
1
BBa_K1319106
range2442863
1
1639
1653
annotation2442864
1
BBa_K1615067
range2442864
1
1654
3213
annotation2442861
1
BBa_K314103
range2442861
1
1
1638
BBa_K1319106
1
Scar25 ATG
RFC 25 Translation Start Scar Sequence
2014-10-02T11:00:00Z
2015-05-08T01:09:51Z
This sequence is produced by an assembly method.
This sequence is produced by RFC10-assembly of a RFC10-RBS with a RFC25-prefixed part.
false
false
_1694_
0
19522
9
Not in stock
false
The resulting sequence is a combination of the RFC10 RBS-CDS scar (tactag) and 9 nucleotides from the RFC25 prefix (atg gcc ggc).
false
Michael Osthege
annotation2393317
1
start
range2393317
1
7
9
BBa_K314103
1
BBa_K314103
Lac induced expression cassette
2010-10-07T11:00:00Z
2015-05-08T01:11:55Z
construct
Released HQ 2013
Lac induced protein expression insert includes f1 origin, Lac I gene and RBS
false
false
_496_
0
6395
9
In stock
true
false
Tomas Huber, Justin Siegel
component2091082
1
BBa_K314111
component2091089
1
BBa_B0034
component2091081
1
BBa_K314110
component2091083
1
BBa_R0011
annotation2091082
1
BBa_K314111
range2091082
1
464
1555
annotation2091089
1
BBa_B0034
range2091089
1
1627
1638
annotation2091083
1
BBa_R0011
range2091083
1
1564
1617
annotation2091081
1
BBa_K314110
range2091081
1
1
455
BBa_K314110_sequence
1
acgcgccctgtagcggcgcattaagcgcggcgggtgtggtggttacgcgcagcgtgaccgctacacttgccagcgccctagcgcccgctcctttcgctttcttcccttcctttctcgccacgttcgccggctttccccgtcaagctctaaatcgggggctccctttagggttccgatttagtgctttacggcacctcgaccccaaaaaacttgattagggtgatggttcacgtagtgggccatcgccctgatagacggtttttcgccctttgacgttggagtccacgttctttaatagtggactcttgttccaaactggaacaacactcaaccctatctcggtctattcttttgatttataagggattttgccgatttcggcctattggttaaaaaatgagctgatttaacaaaaatttaacgcgaattttaacaaaatattaacgtttacaatt
BBa_B0034_sequence
1
aaagaggagaaa
BBa_K1615067_sequence
1
atgtctcgtttccatagccttttagcattcgtggtcgcgtccctggccgcggtggcgcacgcaggcatcgggccagtagctgatctgacgattacgaatgcagcagtgagtcctgatggattctcccgtcaggcagtcgtggtaaatggtggcactcccgggcccctgatcacaggtaatatgggggatcgttttcagctgaacgtgattgataatctgactaaccatacgatgttaaaatccaccagcattcattggcatggctttttccagaaaggtacgaattgggcagatggaccggcgtttatcaatcagtgccctattagcagcgggcatagctttctgtacgatttccaggtgccggatcaagcgggcacgttctggtaccattctcacctgagcacgcagtactgcgacggtctccgtggacctttcgttgtgtatgatccgaacgacccggccgccgatttgtacgacgttgacaacgacgacaccgtcattaccctcgcggactggtaccacgtcgccgcaaaattgggcccggcgtttcccctgggcgccgatgcaacgctgatcaatggcaaagggcgcagtccaagtacgacaacagcagatctcaccgtgatttctgtcaccccgggtaaacgttatcgcttccgcctggtatcccttagctgcgatccgaaccacacgttttctattgacggtcacaacatgacaattattgagacagatagcattaacaccgcccccctggtggtcgactcaatccagatctttgctgcgcagcgctactcatttgttctggaagccaaccaggcagttgataattattggatccgtgcgaacccttcgttcggcaatgttgggttcactggcggcatcaactccgccatcctgcgctacgacggggcggcggcgattgaaccgaccactacccagaccacgtcgactgaaccgcttaacgaggtcaatttgcacccgctggttgcgacggcggtaccgggctctcccgccgctggcggagtggatttggcgatcaatatggcgtttaactttaatggtacgaatttcttcattaacggcgcttcttttactcctccgaccgtgccggttctgctccagattatttcgggggcacagaacgctcaagacctgttaccgtcaggcagcgtctactcgctgccatctaacgcggacattgaaattagctttccagctaccgcagctgcaccgggagcaccgcacccctttcatctccatgggcacgcgtttgctgtagtacgctctgcgggctccacggtttataactacgacaatccgatttttcgtgatgtggtgtcgacgggtacgcccgcagctggcgacaacgtcacaattcgtttccggacggataatcccggtccttggtttctccattgccatatcgactttcacctcgaagcagggtttgccgtagtctttgccgaagatatccctgatgtcgcgtccgcgaacccggtgccgcaagcgtggtcggatctttgtccgacctatgacgcccgcgaccctagctaccag
BBa_K1615068_sequence
1
acgcgccctgtagcggcgcattaagcgcggcgggtgtggtggttacgcgcagcgtgaccgctacacttgccagcgccctagcgcccgctcctttcgctttcttcccttcctttctcgccacgttcgccggctttccccgtcaagctctaaatcgggggctccctttagggttccgatttagtgctttacggcacctcgaccccaaaaaacttgattagggtgatggttcacgtagtgggccatcgccctgatagacggtttttcgccctttgacgttggagtccacgttctttaatagtggactcttgttccaaactggaacaacactcaaccctatctcggtctattcttttgatttataagggattttgccgatttcggcctattggttaaaaaatgagctgatttaacaaaaatttaacgcgaattttaacaaaatattaacgtttacaatttactagaggtggtgaatgtgaaaccagtaacgttatacgatgtcgcagagtatgccggtgtctcttatcagaccgtttcccgcgtggtgaaccaggccagccacgtttctgcgaaaacgcgggaaaaagtggaagcggcgatggcggagctgaattacattcccaaccgcgtggcacaacaactggcgggcaaacagtcgttgctgattggcgttgccacctccagtctggccctgcacgcgccgtcgcaaattgtcgcggcgattaaatctcgcgccgatcaactgggtgccagcgtggtggtgtcgatggtagaacgaagcggcgtcgaagcctgtaaagcggcggtgcacaatcttctcgcgcaacgcgtcagtgggctgatcattaactatccgctggatgaccaggatgccattgctgtggaagctgcctgcactaatgttccggcgttatttcttgatgtctctgaccagacacccatcaacagtattattttctcccatgaagacggtacgcgactgggcgtggagcatctggtcgcattgggtcaccagcaaatcgcgctgttagcgggcccattaagttctgtctcggcgcgtctgcgtctggctggctggcataaatatctcactcgcaatcaaattcagccgatagcggaacgggaaggcgactggagtgccatgtccggttttcaacaaaccatgcaaatgctgaatgagggcatcgttcccactgcgatgctggttgccaacgatcagatggcgctgggcgcaatgcgcgccattaccgagtccgggctgcgcgttggtgcggacatctcggtagtgggatacgacgataccgaagacagctcatgttatatcccgccgttaaccaccatcaaacaggattttcgcctgctggggcaaaccagcgtggaccgcttgctgcaactctctcagggccaggcggtgaagggcaatcagctgttgcccgtctcactggtgaaaagaaaaaccaccctggcgcccaatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtgatactagagaattgtgagcggataacaattgacattgtgagcggataacaagatactgagcacatactagagaaagaggagaaatactagatggccggcatgtctcgtttccatagccttttagcattcgtggtcgcgtccctggccgcggtggcgcacgcaggcatcgggccagtagctgatctgacgattacgaatgcagcagtgagtcctgatggattctcccgtcaggcagtcgtggtaaatggtggcactcccgggcccctgatcacaggtaatatgggggatcgttttcagctgaacgtgattgataatctgactaaccatacgatgttaaaatccaccagcattcattggcatggctttttccagaaaggtacgaattgggcagatggaccggcgtttatcaatcagtgccctattagcagcgggcatagctttctgtacgatttccaggtgccggatcaagcgggcacgttctggtaccattctcacctgagcacgcagtactgcgacggtctccgtggacctttcgttgtgtatgatccgaacgacccggccgccgatttgtacgacgttgacaacgacgacaccgtcattaccctcgcggactggtaccacgtcgccgcaaaattgggcccggcgtttcccctgggcgccgatgcaacgctgatcaatggcaaagggcgcagtccaagtacgacaacagcagatctcaccgtgatttctgtcaccccgggtaaacgttatcgcttccgcctggtatcccttagctgcgatccgaaccacacgttttctattgacggtcacaacatgacaattattgagacagatagcattaacaccgcccccctggtggtcgactcaatccagatctttgctgcgcagcgctactcatttgttctggaagccaaccaggcagttgataattattggatccgtgcgaacccttcgttcggcaatgttgggttcactggcggcatcaactccgccatcctgcgctacgacggggcggcggcgattgaaccgaccactacccagaccacgtcgactgaaccgcttaacgaggtcaatttgcacccgctggttgcgacggcggtaccgggctctcccgccgctggcggagtggatttggcgatcaatatggcgtttaactttaatggtacgaatttcttcattaacggcgcttcttttactcctccgaccgtgccggttctgctccagattatttcgggggcacagaacgctcaagacctgttaccgtcaggcagcgtctactcgctgccatctaacgcggacattgaaattagctttccagctaccgcagctgcaccgggagcaccgcacccctttcatctccatgggcacgcgtttgctgtagtacgctctgcgggctccacggtttataactacgacaatccgatttttcgtgatgtggtgtcgacgggtacgcccgcagctggcgacaacgtcacaattcgtttccggacggataatcccggtccttggtttctccattgccatatcgactttcacctcgaagcagggtttgccgtagtctttgccgaagatatccctgatgtcgcgtccgcgaacccggtgccgcaagcgtggtcggatctttgtccgacctatgacgcccgcgaccctagctaccag
BBa_K1319106_sequence
1
tactagatggccggc
BBa_K314111_sequence
1
gtggtgaatgtgaaaccagtaacgttatacgatgtcgcagagtatgccggtgtctcttatcagaccgtttcccgcgtggtgaaccaggccagccacgtttctgcgaaaacgcgggaaaaagtggaagcggcgatggcggagctgaattacattcccaaccgcgtggcacaacaactggcgggcaaacagtcgttgctgattggcgttgccacctccagtctggccctgcacgcgccgtcgcaaattgtcgcggcgattaaatctcgcgccgatcaactgggtgccagcgtggtggtgtcgatggtagaacgaagcggcgtcgaagcctgtaaagcggcggtgcacaatcttctcgcgcaacgcgtcagtgggctgatcattaactatccgctggatgaccaggatgccattgctgtggaagctgcctgcactaatgttccggcgttatttcttgatgtctctgaccagacacccatcaacagtattattttctcccatgaagacggtacgcgactgggcgtggagcatctggtcgcattgggtcaccagcaaatcgcgctgttagcgggcccattaagttctgtctcggcgcgtctgcgtctggctggctggcataaatatctcactcgcaatcaaattcagccgatagcggaacgggaaggcgactggagtgccatgtccggttttcaacaaaccatgcaaatgctgaatgagggcatcgttcccactgcgatgctggttgccaacgatcagatggcgctgggcgcaatgcgcgccattaccgagtccgggctgcgcgttggtgcggacatctcggtagtgggatacgacgataccgaagacagctcatgttatatcccgccgttaaccaccatcaaacaggattttcgcctgctggggcaaaccagcgtggaccgcttgctgcaactctctcagggccaggcggtgaagggcaatcagctgttgcccgtctcactggtgaaaagaaaaaccaccctggcgcccaatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtga
BBa_R0011_sequence
1
aattgtgagcggataacaattgacattgtgagcggataacaagatactgagcaca
BBa_K314103_sequence
1
acgcgccctgtagcggcgcattaagcgcggcgggtgtggtggttacgcgcagcgtgaccgctacacttgccagcgccctagcgcccgctcctttcgctttcttcccttcctttctcgccacgttcgccggctttccccgtcaagctctaaatcgggggctccctttagggttccgatttagtgctttacggcacctcgaccccaaaaaacttgattagggtgatggttcacgtagtgggccatcgccctgatagacggtttttcgccctttgacgttggagtccacgttctttaatagtggactcttgttccaaactggaacaacactcaaccctatctcggtctattcttttgatttataagggattttgccgatttcggcctattggttaaaaaatgagctgatttaacaaaaatttaacgcgaattttaacaaaatattaacgtttacaatttactagaggtggtgaatgtgaaaccagtaacgttatacgatgtcgcagagtatgccggtgtctcttatcagaccgtttcccgcgtggtgaaccaggccagccacgtttctgcgaaaacgcgggaaaaagtggaagcggcgatggcggagctgaattacattcccaaccgcgtggcacaacaactggcgggcaaacagtcgttgctgattggcgttgccacctccagtctggccctgcacgcgccgtcgcaaattgtcgcggcgattaaatctcgcgccgatcaactgggtgccagcgtggtggtgtcgatggtagaacgaagcggcgtcgaagcctgtaaagcggcggtgcacaatcttctcgcgcaacgcgtcagtgggctgatcattaactatccgctggatgaccaggatgccattgctgtggaagctgcctgcactaatgttccggcgttatttcttgatgtctctgaccagacacccatcaacagtattattttctcccatgaagacggtacgcgactgggcgtggagcatctggtcgcattgggtcaccagcaaatcgcgctgttagcgggcccattaagttctgtctcggcgcgtctgcgtctggctggctggcataaatatctcactcgcaatcaaattcagccgatagcggaacgggaaggcgactggagtgccatgtccggttttcaacaaaccatgcaaatgctgaatgagggcatcgttcccactgcgatgctggttgccaacgatcagatggcgctgggcgcaatgcgcgccattaccgagtccgggctgcgcgttggtgcggacatctcggtagtgggatacgacgataccgaagacagctcatgttatatcccgccgttaaccaccatcaaacaggattttcgcctgctggggcaaaccagcgtggaccgcttgctgcaactctctcagggccaggcggtgaagggcaatcagctgttgcccgtctcactggtgaaaagaaaaaccaccctggcgcccaatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtgatactagagaattgtgagcggataacaattgacattgtgagcggataacaagatactgagcacatactagagaaagaggagaaa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z