BBa_K163002
1
BBa_K163002
Mussel adhesive protein from Mytilus Edulis (Mefp-5) optimized for E. coli
2008-08-24T11:00:00Z
2015-05-08T01:10:55Z
Waite, et al. "Polyphosphoprotein from the adhesive pads of Mytilus edulis" Biochemistry 40 (9), 2887-2893 (2001). Nucleotide sequence from GeneBank, accession number AF333078
This is the protein Mefp-5 that is secreted by Mytilus Edulis. Mefp-5 is one of the strongest adhesives naturally created, and a powerful anti-biofouling agent. The DNA has been codon optimized for use in E. coli using open-software codon-optimizer at http://genomes.urv.es/OPTIMIZER/. This gene lacks a promoter sequence.
false
false
_261_
0
2866
9
Not in stock
false
This sequence has been codon-optimized for production in E. coli. Mefp-5 contains over 20% molar concentration of L-DOPA, the highest DOPA content of known adhesive proteins secreted by Mytilus Edulis. Mefp-5 also has strong anti-biofouling properties, that could possibly be utilized by such things like pacemakers or heart monitors. Mefp-5 is difficult to obtain from purification of mussel proteins, so being able to obtain Mefp-5 from genetic engineering methods will allow researchers to better learn its properties.
false
Nora Yucel
annotation1980425
1
Suffix
range1980425
1
317
343
annotation1980424
1
Mefp-5 E. coli
range1980424
1
23
316
annotation1980423
1
Start
range1980423
1
23
25
annotation1980422
1
Prefix
range1980422
1
1
20
BBa_K163002_sequence
1
gaattcgcggccgcttctaggcatgaagcttagctgcatcgttctggttctgtttctggtcaccctggcggcgtatagcgatgtgggttcttcgtcttccgaagagtataaaggcggttactacccaggtaacgcttaccactaccacagcggcggttcctaccacggcagcggttaccacggcggttacaaagggaagtattacggcaaagccaaaaaatactactacaaatacaagaactccggcaaatacaaatacctgaaaaaagctcgtaaatatcaccgtaaaggttataagtactacggtggtagtagctactagtagcggcggctccagagatct
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z