BBa_K1639012
1
T7 express
T7 expression system for pSB1C3
2015-09-14T11:00:00Z
2015-09-18T06:55:31Z
It is combination of T7 promoter-terminator with sequences containing restriction enzyme cut sites.
In our project we needed to express two different genes at the same bacteria, but unfortunately because of high repeats of sequences gene synthesizing company couldn't synthesize it. To solve this we just divided our genes into different plasmids and cotransformed it into same bacteria. For coexpression of genes from different plasmids origins have to be compatible, like ColA and ColE1.
pSB1C3 possess ColE1 origin of replication. So it's compatible for expression with plasmid containg ColA origin of replication. But it doesn't contain expression machinery like promoters, terminators. We inserted this part to modify pSB1C3 so that it can be used as expression vector.
false
false
_2056_
20835
24789
9
true
We inserted BamH1 and Sal1 cut sites between T7 promoter and T7 terminator. This part also contain RBS. Any other team can use this part to modify vectors like pSB1C3 to add T7 expression feature. Just clone it with enzymes at prefix and suffix.
false
Nurgeldi Bazarov
annotation2457602
1
T7 promoter
range2457602
1
1
19
annotation2457603
1
T7 bacteriophage RBS
range2457603
1
35
57
annotation2457604
1
T7 terminator
range2457604
1
124
171
BBa_K1639012_sequence
1
taatacgactcactatagggcctgtagaaataattttgtttaactttaagaaggagaggatccagcagcctgagacccgtcgactaataattaacctaggctgctgccaccgctgagcaataacaaaaaacccctcaagacccgtttagaggccccaaggggttatgctagctgaaaggaggaactata
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z