BBa_K1709000
1
LuxI-His
LuxI-His
2015-09-07T11:00:00Z
2015-09-18T04:12:52Z
Sequence is originating from V. fischeri.
Here, the sequence from BBa_C0061 was used and optimized.
Autoinducer synthetase for acyl-homoserine lactones (AHL):
LuxI synthesizes AHL (3OC6HSL). Two molecules of AHL form a complex with two molecules of the LuxR protein. This complex then binds to a palyndromic site on the lux promoter, increasing its transcription rate.
LuxI, LuxR and the right lux promoter are all derived from V. fischeri. In absence of AHL, the right lux promotor only gives weak constitutive expression of downstream genes.
The LuxI gene is fused to a His-tag facilitating gene expression measurements.
false
false
_2129_
25389
25389
9
true
Biobrick BBa_C0061 still contained a Barcode sequence which was deleted.
For our own use, 5 bp were exchanged to create unique restriction sites and to optimize DNA folding.
false
Astrid Deryckere
annotation2446990
1
LuxI Coding Region
range2446990
1
1
579
annotation2446991
1
Polyhistidine-tag
range2446991
1
583
606
annotation2446989
1
ATG Start Codon
range2446989
1
1
3
annotation2446992
1
Ochre Stop Codon
range2446992
1
607
609
BBa_K1709000_sequence
1
atgactataatgataaaaaaatcggattttttggcaattccatcggaagagtataaaggtattctaagtcttcgttatcaagtgtttaagcaaagacttgagtgggacttagttgtagaaaataaccttgaatcagatgagtatgataactcaaatgcagaatatatttatgcttgtgatgatactgaaaatgtaagtggatgctggcgtttattacctacaacaggtgattatatgctgaaaagtgtttttcctgaattgcttggtcaacagagtgctcccaaagatcctaatatagtcgaattaagtcgttttgctgtaggtaaaaatagctcaaagataaataactctgctagtgaaattacaatgaaactatttgaagctatatataaacacgctgttagtcaaggtattacagaatatgtaacagtaacatcaacagcaatagagcgatttttaaagcgtattaaagttccttgtcatcgtattggagacaaagaaattcatgtattaggtgatactaaatcggttgtattatccatgcccatcaatgaacagtttaaaaaagcagtcttaaattcacaccatcaccatcaccatgccgcataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z