BBa_K1718005
1
BBa_K1718005
LuxI and GFP behind a Bxb1 compatible genetic switch
2015-09-14T11:00:00Z
2015-09-18T07:12:53Z
The luxI and GFP come from the distribution kit. See BBa_K1718002 for more details on the switch.
The switch is made up of a strong constitutive promoter followed by a terminator. The terminator is flanked by attB and attP so when in the presence of the Bxb1 invertase, the terminator will be inverted, allowing for expression of LuxI and GFP.
LuxI is necessary for the production of AHL, a signaling molecule.
true
false
_2138_
26137
22016
9
false
When on a high copy plasmid (pSB1C3), there was some leaky expression; therefore, we recommend that this part be used on plasmids with a lower copy number.
false
Michael Donovan
component2456635
1
BBa_K1718002
component2456653
1
BBa_K1718004
annotation2456653
1
BBa_K1718004
range2456653
1
302
1851
annotation2456635
1
BBa_K1718002
range2456635
1
1
293
BBa_K1718004
1
BBa_K1718004
LuxI with GFP
2015-09-14T11:00:00Z
2015-09-15T02:15:57Z
All parts were taken from the iGEM 2015 distribution kit.
This part contains the LuxI gene with an RBS followed by a GFP reporter.
false
false
_2138_
22016
22016
9
false
An RBS was added in front of the LuxI coding region.
false
Michael Donovan
annotation2456622
1
stem_loop
range2456622
1
1427
1470
annotation2456619
1
conserved
range2456619
1
674
677
annotation2456621
1
BBa_B0010
range2456621
1
1416
1495
annotation2456627
1
BBa_I13504
range2456627
1
670
1544
annotation2456613
1
BBa_B0034
range2456613
1
1
12
annotation2456618
1
BBa_B0034
range2456618
1
670
681
annotation2456623
1
BBa_B0012
range2456623
1
1504
1544
annotation2456617
1
Help:Barcodes
range2456617
1
637
661
annotation2456612
1
conserved
range2456612
1
5
8
annotation2456620
1
BBa_E0040
range2456620
1
688
1407
annotation2456626
1
stop
range2456626
1
1537
1537
annotation2456624
1
T7 TE
range2456624
1
1511
1530
annotation2456614
1
luxI
range2456614
1
19
597
annotation2456625
1
polya
range2456625
1
1531
1544
annotation2456630
1
RBS region
range2456630
1
1
24
annotation2456616
1
LVA
range2456616
1
598
629
annotation2456615
1
BBa_C0061
range2456615
1
19
636
BBa_K1718002
1
BBa_K1718002
Genetic Switch for Bxb1 invertase
2015-09-12T11:00:00Z
2015-09-15T02:08:17Z
Sequences are based on the Endy experiments.
This part consists of a strong Anderson promoter and a terminator flanked by attB and attP, the recognition sites for BxbI. In its off position, the terminator prevents expression of the downstream part. If the BxbI invertase is expressed, it will recognize the attB and attP sites and invert the DNA; thus, flipping the terminator so polymerase can pass through the gate.
The Bxb1 invertase flips DNA using the attB and attP sites. There is a Bxb1 excisionase that can flip the DNA back.
false
false
_2138_
0
22016
22016
9
It's complicated
false
The design consists of a terminator to stop transcription from the strong constitutive promoter.
false
Daren Kraft and Josephina Hendrix
BBa_K1718005_sequence
1
aaaaaatttatttgctttcgcatctttttgtacctataatgtgtggaaagcttagctagctcggccggcttgtcgacgacggcggtctccgtcgtcaggatcatccgggcccggcttatcggtcagtttcacctgatttacgtaaaaacccgcttcggcgggtttttgcttttggaggggcagaaagatgaatgactgtccacgacgctatacccaaaagaaagggtttgtaccgtacaccactgagaccgcggtggttgaccagacaaaccacgaagctgtcaccggatgtgtactagagttcattaaagaggagaaaggtaccatgactataatgataaaaaaatcggattttttggcaattccatcggaggagtataaaggtattctaagtcttcgttatcaagtgtttaagcaaagacttgagtgggacttagttgtagaaaataaccttgaatcagatgagtatgataactcaaatgcagaatatatttatgcttgtgatgatactgaaaatgtaagtggatgctggcgtttattacctacaacaggtgattatatgctgaaaagtgtttttcctgaattgcttggtcaacagagtgctcccaaagatcctaatatagtcgaattaagtcgttttgctgtaggtaaaaatagctcaaagataaataactctgctagtgaaattacaatgaaactatttgaagctatatataaacacgctgttagtcaaggtattacagaatatgtaacagtaacatcaacagcaatagagcgatttttaaagcgtattaaagttccttgtcatcgtattggagacaaagaaattcatgtattaggtgatactaaatcggttgtattgtctatgcctattaatgaacagtttaaaaaagcagtcttaaatgctgcaaacgacgaaaactacgctttagtagcttaataactctgatagtgctagtgtagatctctactagagaaagaggagaaatactagatgcgtaaaggagaagaacttttcactggagttgtcccaattcttgttgaattagatggtgatgttaatgggcacaaattttctgtcagtggagagggtgaaggtgatgcaacatacggaaaacttacccttaaatttatttgcactactggaaaactacctgttccatggccaacacttgtcactactttcggttatggtgttcaatgctttgcgagatacccagatcatatgaaacagcatgactttttcaagagtgccatgcccgaaggttatgtacaggaaagaactatatttttcaaagatgacgggaactacaagacacgtgctgaagtcaagtttgaaggtgatacccttgttaatagaatcgagttaaaaggtattgattttaaagaagatggaaacattcttggacacaaattggaatacaactataactcacacaatgtatacatcatggcagacaaacaaaagaatggaatcaaagttaacttcaaaattagacacaacattgaagatggaagcgttcaactagcagaccattatcaacaaaatactccaattggcgatggccctgtccttttaccagacaaccattacctgtccacacaatctgccctttcgaaagatcccaacgaaaagagagaccacatggtccttcttgagtttgtaacagctgctgggattacacatggcatggatgaactatacaaataataatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_K1718004_sequence
1
ttcattaaagaggagaaaggtaccatgactataatgataaaaaaatcggattttttggcaattccatcggaggagtataaaggtattctaagtcttcgttatcaagtgtttaagcaaagacttgagtgggacttagttgtagaaaataaccttgaatcagatgagtatgataactcaaatgcagaatatatttatgcttgtgatgatactgaaaatgtaagtggatgctggcgtttattacctacaacaggtgattatatgctgaaaagtgtttttcctgaattgcttggtcaacagagtgctcccaaagatcctaatatagtcgaattaagtcgttttgctgtaggtaaaaatagctcaaagataaataactctgctagtgaaattacaatgaaactatttgaagctatatataaacacgctgttagtcaaggtattacagaatatgtaacagtaacatcaacagcaatagagcgatttttaaagcgtattaaagttccttgtcatcgtattggagacaaagaaattcatgtattaggtgatactaaatcggttgtattgtctatgcctattaatgaacagtttaaaaaagcagtcttaaatgctgcaaacgacgaaaactacgctttagtagcttaataactctgatagtgctagtgtagatctctactagagaaagaggagaaatactagatgcgtaaaggagaagaacttttcactggagttgtcccaattcttgttgaattagatggtgatgttaatgggcacaaattttctgtcagtggagagggtgaaggtgatgcaacatacggaaaacttacccttaaatttatttgcactactggaaaactacctgttccatggccaacacttgtcactactttcggttatggtgttcaatgctttgcgagatacccagatcatatgaaacagcatgactttttcaagagtgccatgcccgaaggttatgtacaggaaagaactatatttttcaaagatgacgggaactacaagacacgtgctgaagtcaagtttgaaggtgatacccttgttaatagaatcgagttaaaaggtattgattttaaagaagatggaaacattcttggacacaaattggaatacaactataactcacacaatgtatacatcatggcagacaaacaaaagaatggaatcaaagttaacttcaaaattagacacaacattgaagatggaagcgttcaactagcagaccattatcaacaaaatactccaattggcgatggccctgtccttttaccagacaaccattacctgtccacacaatctgccctttcgaaagatcccaacgaaaagagagaccacatggtccttcttgagtttgtaacagctgctgggattacacatggcatggatgaactatacaaataataatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_K1718002_sequence
1
aaaaaatttatttgctttcgcatctttttgtacctataatgtgtggaaagcttagctagctcggccggcttgtcgacgacggcggtctccgtcgtcaggatcatccgggcccggcttatcggtcagtttcacctgatttacgtaaaaacccgcttcggcgggtttttgcttttggaggggcagaaagatgaatgactgtccacgacgctatacccaaaagaaagggtttgtaccgtacaccactgagaccgcggtggttgaccagacaaaccacgaagctgtcaccggatgtg
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z