BBa_K1745001
1
KaiABC
KaiABC Oscillator
2015-09-16T11:00:00Z
2015-09-18T12:10:38Z
The KaiABC circadian oscillator is endogenous to the cynanobacterial species Synechococcus elongatus.
pMC001 exhibits the three Kai proteins: KaiA, KaiB, and KaiC, which constitute a circadian oscillator. This biobrick can be used to drive circadian processes. Oscillations can be tracked through the phosphorylation states of KaiC.
false
false
_2167_
26239
26239
9
false
In vitro investigations of this modular system revealed that the robustness of oscillations was sensitive to stoichiometric ratios of KaiA to KaiC (Nakajima, Science 2015). To experiment with these stoichiometric ratios, KaiB and KaiC expression are driven under a constitutive promoter (Part J23100) while KaiA expression is driven under a L-rhamnose inducible promoter (Part K914003).
false
Mansi Chandra
annotation2467393
1
Constitutive BBa_J23100
range2467393
1
3013
3045
annotation2467389
1
Kai C
range2467389
1
1091
2652
annotation2467386
1
RBS BBa_B0034
range2467386
1
127
138
annotation2467387
1
Kai A
range2467387
1
144
1001
annotation2467391
1
Kai B
range2467391
1
2677
2983
annotation2467390
1
RBS BBa_B0034
range2467390
1
2658
2670
annotation2467388
1
Double Terminator BBa_B0014
range2467388
1
1002
1090
annotation2467385
1
pRha Inducible BBa_K914003
range2467385
1
1
121
annotation2467392
1
RBS BBa_B0034
range2467392
1
2990
3006
BBa_K1745001_sequence
1
ccacaattcagcaaattgtgaacatcatcacgttcatctttccctggttgccaatggcccattttcctgtcagtaacgagaaggtcgcgtattcaggcgctttttagactggtcgtaatgaaggtaccaaagaggagaaaggtaccgtgctctcgcaaattgcaatctgcatttgggtggaatcgacggcaattttgcaggattgccagcgggcgctgtcggccgatcgctatcaactccaagtctgtgagtctggcgaaatgctcttggagtatgcccaaacccatcgtgaccaaatcgactgcctgattttagtggcagccaatcccagcttcagggcagttgttcagcagctctgctttgagggagtggtggtaccagcgattgtcgtaggcgatcgcgacagtgaggatcccgatgaaccagccaaagaacagctctatcacagcgctgaactgcacctcggtatccatcagctcgagcaattgccctaccaagttgatgctgcactggctgaatttctgcgcttagccccggtcgagaccatggccgaccacatcatgctgatgggggccaaccacgatcccgagctatcgagccagcagcgggacctcgctcagcgactacaagagcgcctaggctatctcggggtctactacaagcgtgatcccgatcgctttctgcgcaacctacccgcctacgaaagccaaaagctgcaccaagcgatgcagactagctatcgtgaaatcgttttgagctatttttcgccgaatagcaacctcaaccagagcattgacaacttcgtcaacatggctttctttgccgatgttccagtcaccaaagtggtagaaattcacatggagctgatggacgagtttgccaagaagctccgcgtagagggacgttcagaggacattttgctggattatcggctgactttaattgatgtaattgcacatctttgtgagatgtatcgacggtctatcccacgagaaacctgatcacactggctcaccttcgggtgggcctttctgcgtttatatactagagagagaatataaaaagccagattattaatccggcttttttattatttctagctctccggccctttttcttgaacgccgcgcacaattcgcgagagttcgcttttctcatcgacggtaatccgtgttggcgaacctgaaataatccgctcaaagttccggaaagaatccttgatgtccggccctttgtcgctgatcataaattcgcggattgctttgtcatgccaagatccgcgcatcttgaagacgttaatggcgcgggacatttcgccacgaatctcgacgtattggagcaagataatcgtatccgtaattgttgagatatgggagtcagtaatcgaatgcgctcccataaattgatcactggtatttgtgaatagtcccgtgatttcttcttgtttcgcgtagccagtgacaccaattacaaattggcggaaggcattgttgctaacgccccgcgccaaagcagagagggagtcgattgcaatacgagctggcttaaagtcattgatctccgacttaataatctgcaaatggtcttcaaggcctgcggattcaggataggcgcaaacaattttgaggaggttttggcgctccatctcctcaaagtccattccccatgaataggcattgcggagcagctgagctcgtgactcttcataagcgaacagaatcgcccgctctttgttagcacaagcattctcaacgaaacggctaactaacagagttttaccagtgcctgtagcgccagttgccagaatgattgagtccttaaagaagcccccaccacacatttcatcgagtcggacgacaccagatgaaacacgcacgttcgacgatcgctgcgtaaggcgcattgccccgagcgggaagatattgatgccatgatccgtaatcgtgaacggatattcccctttcatgtggctggtgccacgtagcttgaggatttcgagggtgcggcgacggcgctccccttccaaaacgttgcggagaatcacgacgttatcggagacaaattcctcaacaccgtaacgagcgatcgggccatattcctcgatacgctcggtggtcatgaccgtagttgccccaatttgttttaggcgagctaccaaccgaaagagttcgcggcgaaccacagaagaggcatcatattgctggaaaacggacgtgaccgagtcaattgaaacccgccgcgctcgatacttttgaattgcataattaatccgctcaatcagagcagagagatcgaagccgccaacaacctcttgaccttctggatcgggtgaagcatcaagaataaatagtttgccctcatcgaccagcttggctaaatcccagccaaaactacgggcgtttttaatgatatcttgcggggtttcttcgaaagtaacgaaaaccccaggctcatcaaactcgataataccgttatagagaaattgaatagaaaaaagggtcttgccggttcctgaagtaccactaacgagggtcgatcgcccgattggaagaccgccatgactaatatcatcaaagccttcaatcatcgtgcgcatcttagcgatggcttggtgctcagaattattattagggctagtcatctcagcggaagtcatggtacctttctcctctttggtaccttagaagtcgtcggaatcttgaagttcgccgtagagtaaatcaaggccaatcaaaactttctcacggtcggataaatcaccaataatccgtcggacaggcagtggtagaaccttggcgagggttggcgtcgctaggattttatcctcttctgccaactgaggatttttgagaacatcgatcacctttagagcataaacaccttgaaattcaacttcgagaatgttcttgagcgttttgagggcacggactgagtttggagtattgccggcgacgtagagcttgagaatgtaggttttacgagggctcatggtacctttctcctctttggtaccgctagcactgtacctaggactgagctagccgtcaa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z