BBa_K1763421
1
BBa_K1763421
PCquad Mutant 10
2015-09-10T11:00:00Z
2016-10-02T06:33:24Z
Bromoperoxidase (trimer) and M1 Virus Matrix Protein (dimer) linked with an alpha helix.
Subunit of a 12-subunit protein cage with a thrombin cleavage sequence inserted between residues 243 and 248 (ALPSAE to ALPGLVPRGSGSAE).
false
false
_2185_
27134
27528
9
false
Considered the area to insert the cleavage sequence. This mutation was selected by examining the secondary structure to ensure minimal disruption of existing alpha-helices or beta sheets, sites were sandwiched by glycine residues, and used PyMOL to check if the site would be accessible to the protease. Geometric accessibility by the protease thrombin and minimal speculated extent of conformational changes by insertion.
false
Tyler Lee
annotation2467610
1
Scar
range2467610
1
34
39
annotation2467628
1
6x His Tag
range2467628
1
1386
1400
annotation2467612
1
Start
range2467612
1
40
42
annotation2467630
1
PCquad Mutant 10
range2467630
1
40
1385
annotation2467611
1
Double Stop
range2467611
1
1425
1430
annotation2467609
1
RBS
range2467609
1
24
28
annotation2467608
1
T7 Promoter
range2467608
1
1
22
BBa_K1763421_sequence
1
taatacgactcactatagggaaagaggagaaatactagatgccgttcattaccgtaggacaagaaaattctacgtctattgatttgtattatgaggaccatggtaccggtacgccggtggttctcatccacggctttccgctatcaggacattcttgggagcgtcagagcgctgcgcttttagatgccggtgctcgtgtaataacgtacgatagacgcggttttggccagagctctcagccaacgactggatacgattatgacaccttcgccgccgatttaaatactgttctggaaaccctggatcttcaggatgcggtcttagttggttttagtatgggcacaggtgaagttgcccgctacgtcagttcttatggcactgctcgtattgcagcggtagcttttctggctagcttagaaccctttctattaaaaaccgatgataatccggatggggcggctccacaggagtttttcgacggaattgtggccgctgtgaaagccgatagatatgctttctatactgggtttttcaatgacttctataatttagatgaaaacctgggaacacgcatctcggaagaggctgtacggaactcatggaatactgcggcatctggcggattctttgctgccgcagccgcgccgaccacttggtatacagattttcgtgcggacattcctagaattgatgtacctgccctgattctgcacggtacgggcgaccgtaccttaccgattgagaacactgcccgcgtctttcataaagctcttccgggcctggttccccgcggttcaggctccgctgagtacgtagaggttgaaggggcacctcatggtctgttatggactcatgctgaagaagtcaacacagccctgcttgctttccttgcgaaggctcaagaagcccaaaagcagaaattactgaccgaagtggaaacttatgtactatccatcataccgtctggtccccttaaagcagaaatcgcacaacgtctggaggatgtcttcgcgggcaaaaatacagacctggaggtgctgatggaatggcttaagacccgaccgattctgtcaccgttaacgaagggtatcctaggattcgtttttaccctgacggtgcccagtgagcgcggactgcaacgaagaagattcgtccaaaacgcattaaacgggaatggtgacccaaacaatatggacaaagcggtgaagctgtatcgaaaacttaagcgcgaaataacattccatggggccaaagaaattagcctgagctattccgctggggcgcttgcttcttgtatgggtttaatatataaccgaatgggtgcggtcaccacggaagtcgcgttcggattagtatgcgcgacatgcgagcagattgcagactctcagcatagaagccatcgtcagcatcaccaccatcaccattaataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z