BBa_K1777005
1
BBa_K1777005
flexible linker with SV40 NLS
2015-09-12T11:00:00Z
2015-09-19T11:42:57Z
This part is improved from BBa_K1486003.
This is a 40-50A flexible separation for fusion domains with a SV40 NLS, and its codon is optimized for mammalian. It can be used to link different protein domains for fusion proteins locating in cell nucleus.
false
false
_2199_
27798
25645
9
false
The codon is optimized for mammalian, and we insert a NLS to promote locating in cell nucleus. Besides ,we lengthen this linker to provide better separation of two domains. At last we avoid tandem repeat sequence(like GGGSPKKKRKVGGGS), which will facilitate fusing this linker to your domains via overlap PCR.
false
Xuhang Li
annotation2476145
1
artificial GS linker
range2476145
1
45
59
annotation2476147
1
artificial GS linker
range2476147
1
110
124
annotation2476144
1
natural flexible linker
range2476144
1
3
23
annotation2476143
1
SV40 NLS
range2476143
1
89
109
annotation2476142
1
SV40 NLS
range2476142
1
24
44
annotation2476139
1
the first linker
range2476139
1
3
59
annotation2476141
1
scar from 3A assembly
range2476141
1
60
67
annotation2476146
1
natural flexible linker
range2476146
1
68
88
annotation2476140
1
the second linker
range2476140
1
68
124
BBa_K1777005_sequence
1
agcctcctccataccagcctctccccaagaagaagagaaaggtgggcggcggcggcagctactagagcctcctccataccagcctctccccaagaagaagagaaaggtgggcggcggcggcagc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z