BBa_K1808008 1 BBa_K1808008 Amorpha-4,11-diene synthase His tagged 2015-09-15T11:00:00Z 2015-09-16T11:25:53Z Artemisia annua This is the coding region of the ADS gene from Artemisia annua with added biobrick suffix and prefix in a pSB1C3 plasmid backbone and a 6 his tagged component. This part is an element of TCD iGEM 2015 set of parts for the synthesis of the anti-malarial drug precursor dihydroartemisinic acid in E. coli. This particular part codes for Amorpha-4-11-diene synthase, which is an enzyme that catalyses the first step in the synthesis of antimalarial drug artemisinin by converting farnesyl diphosphate into amorpha-4,11-diene, which undergoes multiple steps to become dihydroartemisinic acid and finally artemisinin. This part is codon optimised for BioBrick 3A assembly and expression in E. coli cells as well as protein purification. false false _2233_ 26124 26124 9 false This part is codon optimised for BioBrick 3A assembly and expression in E. coli cells as well as protein purification. false Remsha Afzal annotation2461324 1 6 HIS TAG range2461324 1 1639 1656 annotation2461323 1 ADS range2461323 1 1 1659 BBa_K1808008_sequence 1 atggcattaacggaggaaaaaccgattcgtccaattgccaattttcctccatctatttggggggaccagtttctgatctacgagaagcaggtagaacagggcgtggaacagatcgtcaacgacctgaaaaaagaagttcgccaactgctgaaagaagcgctggatattccgatgaaacatgctaatcttctgaaactgatcgatgaaatccagcgcctgggcatcccctatcacttcgagcgtgagattgatcatgcgttacaatgcatctacgagacttacggcgataattggaacggagatcgttctagtttgtggttccggctgatgcgtaaacagggctattatgtgacttgcgatgtttttaacaattacaaagacaaaaacggcgcgtttaaacaatctttggccaacgacgtagaaggcctgctggagctttatgaagccacgtcaatgcgcgtccctggggagattatcctcgaagacgcactcggcttcacacgctcccgcttaagcatcatgaccaaggatgcttttagtacaaacccggccctctttacggaaattcagcgtgcgttgaagcagccgttgtggaagcgcctcccgcgcattgaagcagcccaatacatcccgttctaccagcagcaggatagccacaacaaaactctgctgaaattagctaaactcgagtttaacctgttacaatcactgcacaaagaagagttgagtcacgtctgtaaatggtggaaagcattcgatattaaaaagaacgcaccctgccttcgcgaccgtatcgttgaatgttatttttggggtcttggttctggctatgaaccccagtactcccgtgcgcgcgtgttctttaccaaagcagttgctgtcattacactgattgatgatacgtatgatgcgtacgggacctacgaagaactgaagatctttaccgaagcggtcgagcgctggagcattacgtgcttagacactctgcccgaatacatgaagcctatctacaaactgttcatggatacgtatacggagatggaagaatttctggccaaggaaggccgcaccgatcttttcaattgcggcaaagagtttgtaaaagagtttgtgcgtaacctgatggtggaagctaaatgggccaacgaaggacacattcctacgactgaagaacacgaccccgtggttattattaccggtggtgcaaacctgcttacgaccacgtgctacttgggcatgagcgacattttcaccaaagaatcagttgaatgggcggtcagcgcccccccgctgtttcgttatagcggtattttaggtcgccgcctgaatgatctgatgacccataaagcggaacaagagcgcaaacatagctcgtcgagcctggaatcctatatgaaggagtataacgttaacgaggaatatgcgcagaccttgatttacaaggaagtagaagatgtctggaaagatattaaccgtgaatatttaaccaccaaaaatatcccgcggccgctcctcatggctgtaatttatctgtgtcagtttctggaagtacagtatgcggggaaagataatttcacccgcatgggcgatgagtataaacatctgatcaagagcctcttagtctatccaatgagcattcatcaccatcaccatcactaa igem2sbol 1 iGEM to SBOL conversion Conversion of the iGEM parts registry to SBOL2.1 Chris J. Myers James Alastair McLaughlin 2017-03-06T15:00:00.000Z