BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_K1809035
1
BBa_K1809035
IAFGP
2015-08-25T11:00:00Z
2015-08-26T09:49:51Z
Taken from the tick Ixodes scapularis. Pubmed ID: 20739755
Antifreeze proteins (AFPs) are molecules with the unique property of binding and shaping ice crystals, preventing their growth into relatively large cell-lysing structures (Davies and Sykes 1997). They exhibit a property known as thermal hysteresis, whereby their activity decreases the freezing point of water without changing the melting point. This property allows organisms which produce AFPs to survive colder conditions. Additionally, AFPs have shown biolfilm inhibiting properties, potentially giving them uses in medical applications.
false
false
_2234_
24831
24831
9
false
Codon optimized the sequence for E. coli and to minimize repetitive sequences; removed illegal restriction sites.
false
David Morgan
BBa_K1809036
1
BBa_K1809036
Const. Promoter-RBS-BclA-IAFGP-DT
2015-09-02T11:00:00Z
2016-02-12T09:31:15Z
Composite of parts BBa_K1423005 and BBa_K1809035 without the YFP tag.
This part contains the constitutive promoter BBa_J23100, an RBS, the cell surface expression tag BclA, Ixodes capularis antifreeze glycoprotein (IAFGP), and a double terminator. It encodes an antifreeze protein that attaches to the cell surface.
false
false
_2234_
4206
24831
9
false
Spliced together a cell surface expression tag and the antifreeze protein to test cell surface activity.
false
David Morgan
component2443204
1
BBa_K1809035
component2443202
1
BBa_B0034
component2443207
1
BBa_B0012
component2443205
1
BBa_B0010
component2443203
1
BBa_K1423000
component2443200
1
BBa_J23100
annotation2443207
1
BBa_B0012
range2443207
1
499
539
annotation2443202
1
BBa_B0034
range2443202
1
44
55
annotation2443205
1
BBa_B0010
range2443205
1
411
490
annotation2443203
1
BBa_K1423000
range2443203
1
64
126
annotation2443204
1
BBa_K1809035
range2443204
1
133
402
annotation2443200
1
BBa_J23100
range2443200
1
1
35
BBa_B0012
1
BBa_B0012
TE from coliphageT7
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Derived from the TE terminator of T7 bacteriophage between Genes 1.3 and 1.4 <genbank>V01146</genbank>.
Released HQ 2013
Transcription terminator for the <i>E.coli</i> RNA polymerase.
false
false
_1_
0
24
7
In stock
false
<P> <P>Suggested by Sri Kosuri and Drew Endy as a high efficiency terminator. The 5' end cutoff was placed immediately after the TAA stop codon and the 3' end cutoff was placed just prior to the RBS of Gene 1.4 (before AAGGAG).<P> Use anywhere transcription should be stopped when the gene of interest is upstream of this terminator.
false
Reshma Shetty
annotation1686
1
T7 TE
range1686
1
8
27
annotation7020
1
BBa_B0012
range7020
1
1
41
annotation1687
1
stop
range1687
1
34
34
annotation1690
1
polya
range1690
1
28
41
BBa_K1423000
1
BBa_K1423000
BCLA N-terminal Domain
2014-09-12T11:00:00Z
2015-05-08T01:10:23Z
Bacillus anthracis
This part is the N-terminal domain of BCLA, and it can be used as an anchoring motif for cell surface display. BCLA is a hair-like glycoprotein found on the outermost layer of the Bacillus anthracis spore. It consists of three parts: an N terminal domain, a central domain (also called collagen-like region ???CLR???), and a C terminal domain. A picture of the structure of BCLA can be seen below.
false
false
_1801_
0
22136
9
In stock
false
When designing the part we ensured that BCLA and any following parts would remain in frame. This is essential because as an anchoring motif we expect additional domains to be attached after.
false
Shawna Henry
BBa_J23100
1
BBa_J23100
constitutive promoter family member
2006-08-03T11:00:00Z
2015-08-31T04:08:40Z
Isolated from library of promoters
Released HQ 2013
Replace later
false
true
_52_
0
483
95
In stock
true
N/A
true
John Anderson
BBa_B0010
1
BBa_B0010
T1 from E. coli rrnB
2003-11-19T12:00:00Z
2015-08-31T04:07:20Z
Transcriptional terminator consisting of a 64 bp stem-loop.
false
false
_1_
0
24
7
In stock
false
true
Randy Rettberg
annotation7018
1
BBa_B0010
range7018
1
1
80
annotation4184
1
stem_loop
range4184
1
12
55
BBa_J23100_sequence
1
ttgacggctagctcagtcctaggtacagtgctagc
BBa_B0010_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctc
BBa_K1809036_sequence
1
ttgacggctagctcagtcctaggtacagtgctagctactagagaaagaggagaaatactagaggcgttcgatcctaatctggtaggacccacccttccgccgatcccgccattcacactgccaacatactagatgacaacattattgcgtttaacgattcttatcgttgccgtggcaggcgtattggggagttctaaacgtgcagcacgtgctgctactcctgcaacagcagctacaccggcaactccagctacggctgctaccccagccattgcagcgactccagccacagcagcaacgcctgcgacagcagcgacgccagctcgtaaggcacgtgcagcgacacctgcaactccggcaacgcctgcaacagcagccacgccagcgactgcggcaacataatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_K1423000_sequence
1
gcgttcgatcctaatctggtaggacccacccttccgccgatcccgccattcacactgccaaca
BBa_B0034_sequence
1
aaagaggagaaa
BBa_K1809035_sequence
1
atgacaacattattgcgtttaacgattcttatcgttgccgtggcaggcgtattggggagttctaaacgtgcagcacgtgctgctactcctgcaacagcagctacaccggcaactccagctacggctgctaccccagccattgcagcgactccagccacagcagcaacgcctgcgacagcagcgacgccagctcgtaaggcacgtgcagcgacacctgcaactccggcaacgcctgcaacagcagccacgccagcgactgcggcaacataa
BBa_B0012_sequence
1
tcacactggctcaccttcgggtgggcctttctgcgtttata
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z