BBa_K1824011
1
BBa_K1824011
Constitutive promoter J23119 + Tet O + RBS
2015-09-06T11:00:00Z
2015-09-07T11:08:46Z
J23119, Tet O2 and RBS B0034 were from registry.
This part is a combination of Constitutive promoter J23119, Tet O2 and RBS B0034.
false
false
_2250_
25962
25962
9
false
The TACTAG scar between promoter J23119 and RBS may influence protein production.
false
Zixu Wang
component2445676
1
BBa_K1824889
component2445678
1
BBa_B0034
component2445675
1
BBa_J64991
component2445674
1
BBa_J23119
component2445679
1
BBa_K1824890
annotation2445676
1
BBa_K1824889
range2445676
1
55
62
annotation2445674
1
BBa_J23119
range2445674
1
1
35
annotation2445675
1
BBa_J64991
range2445675
1
36
54
annotation2445678
1
BBa_B0034
range2445678
1
63
74
annotation2445679
1
BBa_K1824890
range2445679
1
75
80
BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_J23119
1
BBa_J23119
constitutive promoter family member
2006-08-23T11:00:00Z
2015-08-31T04:08:40Z
Overlap extension of synthetic oligonucleotides
Released HQ 2013
Later
false
true
_52_
0
483
95
In stock
false
N/A
true
John Anderson
BBa_J64991
1
BBa_J64991
TetR
2007-03-25T11:00:00Z
2015-05-08T01:08:18Z
false
true
_98_
0
1428
98
Not in stock
false
false
Sai Duriseti
BBa_K1824890
1
BBa_K1824890
The Sequence of the SpeI/XbaI scar in BioBricks standard assembly.
2015-09-06T11:00:00Z
2015-09-07T10:05:29Z
It is the scar sequence of 3A assembly.
In most cases, designers usually tend to embedded an appropriate spacer sequence between one individual part and the other. The 3A assembly, a commonly used manipulation method, creating scar between biobricks and, this unique scar usually served as default transcription spacer sequence.
XJTLU-CHINA 2015 used Gibson assembly instead of conventional 3A assembly to create complex parts. If the reader have any interest to read the assembly diagram that the team promoted, they would find out that Gibson assembly was the ideal choices for the project.
Though XJTLU-CHINA used Gibson assembly, which means parts could directly attach to one another without scars, the team still persevered the usually used scar sequence as the spacer. If readers looked through the assembly diagram that the team provided, they would find out that, for the constructs like a promoter part + a RBS part, the team not only embedded the spacer between the promoter and the RBS but also attach a spacer at the end of the RBS part. If the readers know the mechanism of Gibson assembly, they would know that it is for the one of the greatest feature of Gibson assembly, scarless manipulation.
However, this design became problematical when the team registry the parts. Take the mentioned a promoter part + a RBS part as a instance, a promoter + a RBS Is usually registered as a composite part. What designers usually do is to enter part number they used in order and generate the new composite part with scars. Nevertheless, for the parts of XJTLU-CHINA, this operation is not applicable because if a promoter part + a RBS part was outputted as a new composite part with scars, there would be no scar remained at the end of RBS part.
To fix this problem, we have to registry several spacer parts and put them into our composite parts in the manner of generating blunt end.
false
false
_2250_
25962
25962
9
false
It part is unnecessary for the teams that use 3A assembly.
false
Wenbo Xu
BBa_K1824889
1
BBa_K1824889
A Transcriptional Spacer Sequence
2015-09-05T11:00:00Z
2015-09-07T10:21:43Z
E. coli promoter for tetracycline efflux protein gene
Bacterial operator O2 for the tetR and tetA genes
false
false
_2250_
25962
25962
9
Not in stock
false
This is the second operator of pTet
false
Wenbo Xu
BBa_B0034_sequence
1
aaagaggagaaa
BBa_J64991_sequence
1
tccctatcagtgatagaga
BBa_K1824890_sequence
1
tactag
BBa_K1824011_sequence
1
ttgacagctagctcagtcctaggtataatgctagctccctatcagtgatagagatactagagaaagaggagaaatactag
BBa_K1824889_sequence
1
tactagag
BBa_J23119_sequence
1
ttgacagctagctcagtcctaggtataatgctagc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z