BBa_K1855005
1
BBa_K1855005
BclA-Zif268
2015-09-16T11:00:00Z
2015-09-17T03:13:15Z
BclA is originally from Bacillus Anthracis; Zif268 is from mice.
A fusion protein of a transmembrane domain (BclA) and a zinc-finger domain (Zif268 1AAY fragment),under pL_lac promotion and containing a C-terminal FLAG tag. It is used to exhibit a zinc-finger dsDNA binding domain complimentary to CCGCCCNCGC on the cell surface of E.coli.
false
false
_2282_
27125
27125
9
false
We had to optimise the codon for E.coli K12, and then alter the codon slightly to remove unwanted cut sites. The BclA domain is preceeded by an NdeI cut site, and followed by an AgeI cut site. The Zif268 fragment domain is preceeded by an NheI cut site and followed by a ClaI cut site.
false
Iain Galpin
annotation2466916
1
BBa_K864600 T0 Terminator
range2466916
1
570
621
annotation2466913
1
Zif268
range2466913
1
192
458
annotation2466911
1
BclA
range2466911
1
84
146
annotation2466909
1
pL_lac
range2466909
1
1
56
annotation2466910
1
B0034 Strong RBS
range2466910
1
60
80
annotation2466915
1
3x FLAG
range2466915
1
492
563
annotation2466912
1
Linker
range2466912
1
150
185
annotation2466914
1
Linker
range2466914
1
465
488
BBa_K1855005_sequence
1
ataaatgtgagcggataacattgacattgtgagcggataacaagatactgagcacattaattaaagaggagaaaggtacccatatggcattcgatccgaatctggttggccctaccctgccaccgattccgccgttcaccctgccgaccggtggctctggcggtggctccggtggcggctccggcgctagcgaacgtccttatgcttgtccagtggagtcttgcgatcgccgtttctcccgtagcgacgaactgacccgtcacatccgtatccacaccggccagaagccgtttcaatgccgtatctgtatgcgtaacttttcccgcagcgatcacctgactacccacatccgtacccatactggtgaaaaaccgttcgcgtgcgatatctgtggtcgcaaattcgcacgcagcgacgaacgcaaacgtcatactaaaattcacctgcgtcagaaagatatcgatggtggcggttccggcggcggttcccatgattataaagatgacgatgacaaagactacaaggacgatgacgacaaggactataaggacgacgacgataagtgataattgttcagaacgctcggtcttgcacaccgggcgttttttctttgtgagtcca
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z