BBa_K1857002
1
BBa_K1857002
HSP70A-RBCS2_Hyg Expression Plasmid
2015-09-15T11:00:00Z
2015-09-18T03:13:45Z
The parts were adapted from pOpt_mVenus_Hyg.
This plasmid is designed to facilitate the easiest expression of proteins possible. It contains an HSP70A-RBCS2 fusion promoter attached to an RBCS2 intron, flanked by the iGEM prefix and suffix. There is an RBCS2 3' UTR after the suffix. Additionally, there is a complete Hygromycin B resistance cassette downstream, allowing for selection.
The suffix can be removed and replaced with the coding sequence of a heterologous protein. Furthermore, the entire fusion-promoter-intron sequence can be removed with the prefix and suffix and replaced by an alternate promoter to compare expression levels between Chlamydomonas promoters.
false
false
_2285_
26495
26495
9
false
We amplified the pHSP70A-RBCS2-Intron region with the iGEM prefix/suffix added to the ends. We then amplified 3'UTR RBCS2 with PstI upstream' and SpeI downstream. The hygromycin B resistance cassette was then amplified with XbaI upstream and SpeI downstream. pSB1C3 was amplified with primers which removed ligated with digested pHSP70A-RBCS2-Intron and pSB1C3 for final assembly.
false
Joshua Timmons
annotation2473744
1
pRBCS2
range2473744
1
274
497
annotation2473743
1
pHSP70A
range2473743
1
1
267
BBa_K1857002_sequence
1
gctgaggcttgacatgattggtgcgtatgtttgtatgaagctacaggactgatttggcgggctatgagggcgggggaagctctggaagggccgcgatggggcgcgcggcgtccagaaggcgccatacggcccgctggcggcacccatccggtataaaagcccgcgaccccgaacggtgacctccactttcagcgacaaacgagcacttatacatacgcgactattctgccgctatacataaccactcagctagcttaagatcccatcaccggtgcatgccgggcgcgccagaaggagcgcagccaaaccaggatgatgtttgatggggtatttgagcacttgcaacccttatccggaagccccctggcccacaaaggctaggcgccaatgcaagcagttcgcatgcagcccctggagcggtgccctcctgataaaccggccagggggcctatgttctttacttttttacaagagaagtcactcaacatcttaaaatggccaggtgagtcgacgagcaagcccggcggatcaggcagcgtgcttgcagatttgacttgcaacgcccgcattgtgtcgacgaaggcttttggctcctctgtcgctgtctcaagcagcatctaaccctgcgtcgccgtttccatttgcaggatgc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z