BBa_K1878006
1
BBa_K1878006
mNarK/iRFP670
2016-10-13T11:00:00Z
2016-10-14T09:08:06Z
The gene sequence was procured from IDT.
Hypoxia inducible iRFP670 with modified NarK promoter
false
false
_2343_
26215
26215
9
false
Fickle.
false
Margaret Lie
component2511715
1
BBa_K239006
component2511716
1
BBa_K1878000
annotation2511715
1
BBa_K239006
range2511715
1
1
89
annotation2511716
1
BBa_K1878000
range2511716
1
96
1031
BBa_K239006
1
BBa_K239006
Modified NarK promoter
2009-06-25T11:00:00Z
2015-05-08T01:11:36Z
Raw genomic sequence from biocyc, Escherichia coli K-12, but modified.
Sequence contains 2 Fnr (one of which is modified), 1 Fis, 2 NarL binding sites and initiates transcription by RNAP sigma-70. Function: Switched on during anaerobic conditions. Area of application: Detection of when the cell is switching to anaerobic metabolism.
false
false
_375_
0
4247
9
It's complicated
false
Detect and remove possible restriction sites: XbaI, EcoRI, PstI, SpeI, AgeI, BamHI, BglII, NogMIV, NotI and XhoI. No restriction site had to be removed. Sequence starts 3 bp before the first FNR binding site and ends 6 pb after the -10 box. One pb has been changed in order optimise the first FNR binding site.
false
Axel Nystrom
annotation2006725
1
NarL
range2006725
1
20
26
annotation2006724
1
Fnr
range2006724
1
4
17
annotation2006720
1
-10
range2006720
1
76
83
annotation2006726
1
NarL
range2006726
1
7
13
annotation2006722
1
Fnr
range2006722
1
42
55
annotation2006721
1
-35
range2006721
1
48
56
annotation2006723
1
Fis
range2006723
1
38
56
BBa_K1878000
1
BBa_K1878000
iRFP670
2016-10-13T11:00:00Z
2016-10-14T04:26:40Z
iRFP670 is a mutated form of the Rhodopseudomonas palustris bacterial phytochrome photoreceptor.
Shcherbakova, D. M. & Verkhusha, V. V. Near-infrared fluorescent proteins for multicolor in vivo imaging. 10, (2013).
iRFP670 is a fluorescent protein that has an excitation wavelength of 643 nm and an emission wavelength of 670 nm. It utilizes billiverdin as a chromophore. The extinction coefficient is 114,000 M−1 cm−1, and the quantum yield is 11.1%. It is twice as bright as iRFP713 (formerly known as iRFP). The photobleaching half-life is 290 s and pKa is 4.0. Near-infrared fluorescent proteins are good for long-term in vivo imaging and exhibit high brightness in bacteria, mammalian cells, and mice.
false
false
_2343_
26215
26215
9
false
The PstI site within the reporter has been removed. There are several BsaI sites within the protein so do not use the BsaI enzyme for Golden Gate DNA Assembly.
false
Margaret Lie
BBa_K1878006_sequence
1
gtattgataaatatcaatgatagataaagttatcttatcgtttgatttacatcaaattgcctttagctacagacactaaggtggcagactactagatgccgcgtaaggtcgatctcacctcctgcgatcgcgagccgatccacatccccggcagcattcagccgtgcggctgcctgctagcctgcgacgcgcaggcggtgcggatcacgcgcattacggaaaatgccggcgcgttctttggacgcgaaactccgcgggtcggtgagctactcgccgattacttcggcgagaccgaagcccatgcgctgcgcaacgcactggcgcagtcctccgatccaaagcgaccggcgctgatcttcggttggcgcgacggcctgaccggccgcaccttcgacatctcactgcatcgccatgacggtacatcgatcatcgagttcgagcctgcggcggccgaacaggccgacaatccgctgcggctgacgcggcagatcatcgcgcgcaccaaagaactgaagtcgctcgaagagatggccgcacgggtgccgcgctatctgcaagcgatgctcggctatcaccgcgtgatgttgtaccgcttcgcggacgacggctccgggatggtgatcggcgaggcgaagcgcagcgacctcgagagctttctcggtcagcactttccggcgtcgctggtcccgcagcaggcgcggctactgtacttgaagaacgcgatccgcgtggtctcggattcgcgcggcatcagcagccggatcgtgcccgagcacgacgcctccggcgccgcgctcgatctgtcgttcgcgcacctgcgcagcatctcgccctgccatctcgaatttctgcggaacatgggcgtcagcgcctcgatgtcgctgtcgatcatcattgacggcacgctatggggattgatcatctgtcatcattacgagccgcgtgccgtgccgatggcgcagcgcgtcgcggccgaaatgttcgccgacttcttatcgctgcacttcaccgccgcccaccaccaacgctaa
BBa_K1878000_sequence
1
atgccgcgtaaggtcgatctcacctcctgcgatcgcgagccgatccacatccccggcagcattcagccgtgcggctgcctgctagcctgcgacgcgcaggcggtgcggatcacgcgcattacggaaaatgccggcgcgttctttggacgcgaaactccgcgggtcggtgagctactcgccgattacttcggcgagaccgaagcccatgcgctgcgcaacgcactggcgcagtcctccgatccaaagcgaccggcgctgatcttcggttggcgcgacggcctgaccggccgcaccttcgacatctcactgcatcgccatgacggtacatcgatcatcgagttcgagcctgcggcggccgaacaggccgacaatccgctgcggctgacgcggcagatcatcgcgcgcaccaaagaactgaagtcgctcgaagagatggccgcacgggtgccgcgctatctgcaagcgatgctcggctatcaccgcgtgatgttgtaccgcttcgcggacgacggctccgggatggtgatcggcgaggcgaagcgcagcgacctcgagagctttctcggtcagcactttccggcgtcgctggtcccgcagcaggcgcggctactgtacttgaagaacgcgatccgcgtggtctcggattcgcgcggcatcagcagccggatcgtgcccgagcacgacgcctccggcgccgcgctcgatctgtcgttcgcgcacctgcgcagcatctcgccctgccatctcgaatttctgcggaacatgggcgtcagcgcctcgatgtcgctgtcgatcatcattgacggcacgctatggggattgatcatctgtcatcattacgagccgcgtgccgtgccgatggcgcagcgcgtcgcggccgaaatgttcgccgacttcttatcgctgcacttcaccgccgcccaccaccaacgctaa
BBa_K239006_sequence
1
gtattgataaatatcaatgatagataaagttatcttatcgtttgatttacatcaaattgcctttagctacagacactaaggtggcagac
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z