BBa_K1896006
1
BBa_K1896006
mGFPuv2 (N-part)
2016-10-12T11:00:00Z
2016-10-14T05:42:05Z
We started from pBAD-GFPuv (GenBank: U62637.1, Clontech), applied the described mutations and codon optimised the sequence for ''E. coli''.
Variant of [[Part:BBa_K1896001|Part:BBa_K1896001]] that lacks stop codons so it can be used in N-terminal protein fusions.
mGFPuv2 contains the following mutations:
* '''F99S/M153T/V163A''': GFPuv or ''cycle 3'' GFP was optimised for excitation by UV light (360-400nm). [1]
* '''S208L''': Almost doubles the fluorescent intensity of GFPuv, resulting in GFPuv2. [2]
* '''A206K''': Monomerizes most GFP variants by disrupting a hydrophobic patch. [3]
false
false
_2362_
19009
19009
9
false
The stop codon was removed to enable scarless N-terminal protein fusions.
false
Bob Van Hove, Maarten Van Brempt
annotation2499182
1
V163A
range2499182
1
487
489
annotation2499179
1
mGFPuv2
range2499179
1
1
714
annotation2499184
1
S208L
range2499184
1
622
624
annotation2499187
1
start
range2499187
1
1
3
annotation2499181
1
M153T
range2499181
1
457
459
annotation2499180
1
F99S
range2499180
1
295
297
annotation2499183
1
A206K
range2499183
1
616
618
BBa_K1896006_sequence
1
atgagtaaaggagaagaacttttcactggagttgtcccaattcttgttgaattagatggtgatgttaatgggcacaaattttctgtcagtggagagggtgaaggtgatgcaacatacggaaaacttacccttaaatttatttgcactactggaaaactacctgttccatggccaacacttgtcactactttctcttatggtgttcaatgcttttcccgttatccggatcatatgaaacggcatgactttttcaagagtgccatgcccgaaggttatgtacaggaacgcactatatctttcaaagatgacgggaactacaagacgcgtgctgaagtcaagtttgaaggtgatacccttgttaatcgtatcgagttaaaaggtattgattttaaagaagatggaaacattctcggacacaaactggagtacaactataactcacacaatgtatacatcacggcagacaaacaaaagaatggaatcaaagctaacttcaaaattcgccacaacattgaagatggctccgttcaactagcagaccattatcaacaaaatactccaattggtgatggccctgtccttttaccagacaaccattacctgtcgacacaatctaaacttttgaaagatcccaacgaaaagcgtgaccacatggtccttcttgagtttgtaactgctgctgggattacacatggcatggatgagctctacaaa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z