BBa_K1896007
1
BBa_K1896007
mGFPuv2 (C-part)
2016-10-12T11:00:00Z
2016-10-14T05:45:10Z
We started from pBAD-GFPuv (GenBank: U62637.1, Clontech), applied the described mutations and codon optimised the sequence for ''E. coli''.
Variant of [[Part:BBa_K1896001|Part:BBa_K1896001]] where the start codon was replaced by a GSTGS linker so it can be used in C-terminal protein fusions.
mGFPuv2 contains the following mutations:
* '''F99S/M153T/V163A''': GFPuv or ''cycle 3'' GFP was optimised for excitation by UV light (360-400nm). [1]
* '''S208L''': Almost doubles the fluorescent intensity of GFPuv, resulting in GFPuv2. [2]
* '''A206K''': Monomerizes most GFP variants by disrupting a hydrophobic patch. [3]
false
false
_2362_
19009
19009
9
false
The start codon was replaced by a GSTGS linker to enable scarless C-terminal protein fusions.
false
Bob Van Hove, Maarten Van Brempt
annotation2502149
1
GSTGS linker
range2502149
1
1
15
annotation2502171
1
stop
range2502171
1
727
729
annotation2502169
1
GFPuv2
range2502169
1
16
729
BBa_K1896007_sequence
1
ggcagcaccggatctagtaaaggagaagaacttttcactggagttgtcccaattcttgttgaattagatggtgatgttaatgggcacaaattttctgtcagtggagagggtgaaggtgatgcaacatacggaaaacttacccttaaatttatttgcactactggaaaactacctgttccatggccaacacttgtcactactttctcttatggtgttcaatgcttttcccgttatccggatcatatgaaacggcatgactttttcaagagtgccatgcccgaaggttatgtacaggaacgcactatatctttcaaagatgacgggaactacaagacgcgtgctgaagtcaagtttgaaggtgatacccttgttaatcgtatcgagttaaaaggtattgattttaaagaagatggaaacattctcggacacaaactggagtacaactataactcacacaatgtatacatcacggcagacaaacaaaagaatggaatcaaagctaacttcaaaattcgccacaacattgaagatggctccgttcaactagcagaccattatcaacaaaatactccaattggtgatggccctgtccttttaccagacaaccattacctgtcgacacaatctaaacttttgaaagatcccaacgaaaagcgtgaccacatggtccttcttgagtttgtaactgctgctgggattacacatggcatggatgagctctacaaataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z