BBa_K1896006
1
BBa_K1896006
mGFPuv2 (N-part)
2016-10-12T11:00:00Z
2016-10-14T05:42:05Z
We started from pBAD-GFPuv (GenBank: U62637.1, Clontech), applied the described mutations and codon optimised the sequence for ''E. coli''.
Variant of [[Part:BBa_K1896001|Part:BBa_K1896001]] that lacks stop codons so it can be used in N-terminal protein fusions.
mGFPuv2 contains the following mutations:
* '''F99S/M153T/V163A''': GFPuv or ''cycle 3'' GFP was optimised for excitation by UV light (360-400nm). [1]
* '''S208L''': Almost doubles the fluorescent intensity of GFPuv, resulting in GFPuv2. [2]
* '''A206K''': Monomerizes most GFP variants by disrupting a hydrophobic patch. [3]
false
false
_2362_
19009
19009
9
false
The stop codon was removed to enable scarless N-terminal protein fusions.
false
Bob Van Hove, Maarten Van Brempt
annotation2499183
1
A206K
range2499183
1
616
618
annotation2499187
1
start
range2499187
1
1
3
annotation2499182
1
V163A
range2499182
1
487
489
annotation2499181
1
M153T
range2499181
1
457
459
annotation2499184
1
S208L
range2499184
1
622
624
annotation2499180
1
F99S
range2499180
1
295
297
annotation2499179
1
mGFPuv2
range2499179
1
1
714
BBa_K1896005
1
BBa_K1896005
mSA2-His
2016-10-12T11:00:00Z
2016-10-14T05:41:52Z
Combination of streptavidin (''Streptomyces avidinii'') and rhizavidin (''Rhizobium etli''), engineered through homology modeling [1].
Variant of [[Part:BBa_K1896000|Part:BBa_K1896000]] for use in scarless C-terminal protein fusions. This part contains a His-tag instead of a terminal AgeI restriction site.
false
false
_2362_
19009
19009
9
false
This part is not compatible with the Freiburg assembly standard ([[Assembly_standard_25|RFC 25]]).
false
Bob Van Hove, Maarten Van Brempt
annotation2499131
1
mSA2
range2499131
1
16
372
annotation2499133
1
stop
range2499133
1
391
396
annotation2499132
1
His-tag
range2499132
1
373
390
annotation2499130
1
GSTGS linker
range2499130
1
1
15
BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_K1896015
1
BBa_K1896015
mGFPuv2-mSA2 generator
2016-10-12T11:00:00Z
2016-10-14T05:27:21Z
todo
todo
false
false
_2362_
19009
19009
9
false
todo
false
Bob Van Hove, Maarten Van Brempt
component2500029
1
BBa_S05347
component2500022
1
BBa_S05361
component2500008
1
BBa_S05355
annotation2500022
1
BBa_S05361
range2500022
1
62
1171
annotation2500008
1
BBa_S05355
range2500008
1
1
55
annotation2500029
1
BBa_S05347
range2500029
1
1180
1308
BBa_S05347
1
BBa_S05347
B0010:B0012
2016-10-11T11:00:00Z
2016-10-12T02:32:06Z
false
false
_9_
19009
19009
9
false
false
Bob Van Hove
component2495234
1
BBa_B0012
component2495232
1
BBa_B0010
annotation2495232
1
BBa_B0010
range2495232
1
1
80
annotation2495234
1
BBa_B0012
range2495234
1
89
129
BBa_J23119
1
BBa_J23119
constitutive promoter family member
2006-08-23T11:00:00Z
2015-08-31T04:08:40Z
Overlap extension of synthetic oligonucleotides
Released HQ 2013
Later
false
true
_52_
0
483
95
In stock
false
N/A
true
John Anderson
BBa_S05361
1
BBa_S05361
K1896006:K1896005
2016-10-12T11:00:00Z
2016-10-13T05:48:33Z
false
false
_9_
19009
19009
9
false
false
Bob Van Hove
component2499845
1
BBa_K1896005
component2499840
1
BBa_K1896006
annotation2499840
1
BBa_K1896006
range2499840
1
1
714
annotation2499845
1
BBa_K1896005
range2499845
1
715
1110
BBa_B0010
1
BBa_B0010
T1 from E. coli rrnB
2003-11-19T12:00:00Z
2015-08-31T04:07:20Z
Transcriptional terminator consisting of a 64 bp stem-loop.
false
false
_1_
0
24
7
In stock
false
true
Randy Rettberg
annotation4184
1
stem_loop
range4184
1
12
55
annotation7018
1
BBa_B0010
range7018
1
1
80
BBa_B0012
1
BBa_B0012
TE from coliphageT7
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Derived from the TE terminator of T7 bacteriophage between Genes 1.3 and 1.4 <genbank>V01146</genbank>.
Released HQ 2013
Transcription terminator for the <i>E.coli</i> RNA polymerase.
false
false
_1_
0
24
7
In stock
false
<P> <P>Suggested by Sri Kosuri and Drew Endy as a high efficiency terminator. The 5' end cutoff was placed immediately after the TAA stop codon and the 3' end cutoff was placed just prior to the RBS of Gene 1.4 (before AAGGAG).<P> Use anywhere transcription should be stopped when the gene of interest is upstream of this terminator.
false
Reshma Shetty
annotation1686
1
T7 TE
range1686
1
8
27
annotation1687
1
stop
range1687
1
34
34
annotation1690
1
polya
range1690
1
28
41
annotation7020
1
BBa_B0012
range7020
1
1
41
BBa_S05355
1
BBa_S05355
J23119:B0034
2016-10-12T11:00:00Z
2016-10-13T12:33:03Z
false
false
_9_
19009
19009
9
false
false
Bob Van Hove
component2499223
1
BBa_B0034
component2499221
1
BBa_J23119
annotation2499223
1
BBa_B0034
range2499223
1
44
55
annotation2499221
1
BBa_J23119
range2499221
1
1
35
BBa_S05355_sequence
1
ttgacagctagctcagtcctaggtataatgctagctactagagaaagaggagaaa
BBa_B0010_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctc
BBa_K1896015_sequence
1
ttgacagctagctcagtcctaggtataatgctagctactagagaaagaggagaaatactagatgagtaaaggagaagaacttttcactggagttgtcccaattcttgttgaattagatggtgatgttaatgggcacaaattttctgtcagtggagagggtgaaggtgatgcaacatacggaaaacttacccttaaatttatttgcactactggaaaactacctgttccatggccaacacttgtcactactttctcttatggtgttcaatgcttttcccgttatccggatcatatgaaacggcatgactttttcaagagtgccatgcccgaaggttatgtacaggaacgcactatatctttcaaagatgacgggaactacaagacgcgtgctgaagtcaagtttgaaggtgatacccttgttaatcgtatcgagttaaaaggtattgattttaaagaagatggaaacattctcggacacaaactggagtacaactataactcacacaatgtatacatcacggcagacaaacaaaagaatggaatcaaagctaacttcaaaattcgccacaacattgaagatggctccgttcaactagcagaccattatcaacaaaatactccaattggtgatggccctgtccttttaccagacaaccattacctgtcgacacaatctaaacttttgaaagatcccaacgaaaagcgtgaccacatggtccttcttgagtttgtaactgctgctgggattacacatggcatggatgagctctacaaaggcagcaccggatctgcggaagcgggtatcaccggcacgtggtacaaccagcatggttctaccttcaccgttaccgcgggtgcggacggtaacctgaccggtcagtacgaaaaccgtgcgcagggcactggttgccagaactctccgtacaccctgaccggtcgttacaacggtaccaaactggaatggcgtgttgaatggaacaactctaccgaaaactgccactctcgtaccgaatggcgtggtcagtaccagggtggtgcggaagcgcgtatcaacacccagtggaacctgacctacgaaggtggttctggtccggcgaccgaacagggtcaggacaccttcaccaaagttaaaccgtctgcggcgtcccatcaccatcaccaccattaataatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_K1896006_sequence
1
atgagtaaaggagaagaacttttcactggagttgtcccaattcttgttgaattagatggtgatgttaatgggcacaaattttctgtcagtggagagggtgaaggtgatgcaacatacggaaaacttacccttaaatttatttgcactactggaaaactacctgttccatggccaacacttgtcactactttctcttatggtgttcaatgcttttcccgttatccggatcatatgaaacggcatgactttttcaagagtgccatgcccgaaggttatgtacaggaacgcactatatctttcaaagatgacgggaactacaagacgcgtgctgaagtcaagtttgaaggtgatacccttgttaatcgtatcgagttaaaaggtattgattttaaagaagatggaaacattctcggacacaaactggagtacaactataactcacacaatgtatacatcacggcagacaaacaaaagaatggaatcaaagctaacttcaaaattcgccacaacattgaagatggctccgttcaactagcagaccattatcaacaaaatactccaattggtgatggccctgtccttttaccagacaaccattacctgtcgacacaatctaaacttttgaaagatcccaacgaaaagcgtgaccacatggtccttcttgagtttgtaactgctgctgggattacacatggcatggatgagctctacaaa
BBa_S05347_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_B0034_sequence
1
aaagaggagaaa
BBa_S05361_sequence
1
atgagtaaaggagaagaacttttcactggagttgtcccaattcttgttgaattagatggtgatgttaatgggcacaaattttctgtcagtggagagggtgaaggtgatgcaacatacggaaaacttacccttaaatttatttgcactactggaaaactacctgttccatggccaacacttgtcactactttctcttatggtgttcaatgcttttcccgttatccggatcatatgaaacggcatgactttttcaagagtgccatgcccgaaggttatgtacaggaacgcactatatctttcaaagatgacgggaactacaagacgcgtgctgaagtcaagtttgaaggtgatacccttgttaatcgtatcgagttaaaaggtattgattttaaagaagatggaaacattctcggacacaaactggagtacaactataactcacacaatgtatacatcacggcagacaaacaaaagaatggaatcaaagctaacttcaaaattcgccacaacattgaagatggctccgttcaactagcagaccattatcaacaaaatactccaattggtgatggccctgtccttttaccagacaaccattacctgtcgacacaatctaaacttttgaaagatcccaacgaaaagcgtgaccacatggtccttcttgagtttgtaactgctgctgggattacacatggcatggatgagctctacaaaggcagcaccggatctgcggaagcgggtatcaccggcacgtggtacaaccagcatggttctaccttcaccgttaccgcgggtgcggacggtaacctgaccggtcagtacgaaaaccgtgcgcagggcactggttgccagaactctccgtacaccctgaccggtcgttacaacggtaccaaactggaatggcgtgttgaatggaacaactctaccgaaaactgccactctcgtaccgaatggcgtggtcagtaccagggtggtgcggaagcgcgtatcaacacccagtggaacctgacctacgaaggtggttctggtccggcgaccgaacagggtcaggacaccttcaccaaagttaaaccgtctgcggcgtcccatcaccatcaccaccattaataa
BBa_B0012_sequence
1
tcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_J23119_sequence
1
ttgacagctagctcagtcctaggtataatgctagc
BBa_K1896005_sequence
1
ggcagcaccggatctgcggaagcgggtatcaccggcacgtggtacaaccagcatggttctaccttcaccgttaccgcgggtgcggacggtaacctgaccggtcagtacgaaaaccgtgcgcagggcactggttgccagaactctccgtacaccctgaccggtcgttacaacggtaccaaactggaatggcgtgttgaatggaacaactctaccgaaaactgccactctcgtaccgaatggcgtggtcagtaccagggtggtgcggaagcgcgtatcaacacccagtggaacctgacctacgaaggtggttctggtccggcgaccgaacagggtcaggacaccttcaccaaagttaaaccgtctgcggcgtcccatcaccatcaccaccattaataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z