BBa_K1913002
1
BBa_K1913002
chiA device regulated by pBAD
2016-09-21T11:00:00Z
2016-09-29T07:17:24Z
Original chiA sequence originates from GQ855217.
This part uses a pBAD promoter (BBa_I0500), weak RBS (BBa_B0032) and a double terminator (BBa_B0015). When induced with arabinose, it will produce chiA. A weak promoter was chosen to prevent formation of inclusion bodies during expression.
false
false
_2380_
29556
29556
9
false
This is a composite part for expression of the chiA protein coding region from BBa_K1913000.
false
Lisa R??ttjers
component2484460
1
BBa_K1913000
component2484454
1
BBa_B0032
component2484467
1
BBa_B0015
component2484452
1
BBa_I0500
annotation2484452
1
BBa_I0500
range2484452
1
1
1210
annotation2484454
1
BBa_B0032
range2484454
1
1219
1231
annotation2484460
1
BBa_K1913000
range2484460
1
1238
2932
annotation2484467
1
BBa_B0015
range2484467
1
2941
3069
BBa_B0032
1
BBa_B0032
RBS.3 (medium) -- derivative of BBa_0030
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
Weak1 RBS based on Ron Weiss thesis. Strength is considered relative to <bb_part>BBa_B0030</bb_part>, <bb_part>BBa_B0031</bb_part>, <bb_part>BBa_B0033</bb_part>.
false
true
_41_44_48_46_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix ("RBS-2" in figure 4-14 of thesis). <P>
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation1709
1
RBS-3\Weak
range1709
1
1
13
annotation7027
1
BBa_B0032
range7027
1
1
13
annotation1710
1
RBS
range1710
1
7
10
BBa_B0010
1
BBa_B0010
T1 from E. coli rrnB
2003-11-19T12:00:00Z
2015-08-31T04:07:20Z
Transcriptional terminator consisting of a 64 bp stem-loop.
false
false
_1_
0
24
7
In stock
false
true
Randy Rettberg
annotation7018
1
BBa_B0010
range7018
1
1
80
annotation4184
1
stem_loop
range4184
1
12
55
BBa_K1913000
1
BBa_K1913000
chiA for Varroa destructor
2016-09-21T11:00:00Z
2016-09-22T06:18:00Z
The source of this part is chiA from Serratia marcescens GEI; accession GQ855217.
Serratia marcescens GEI chiA protein coding region optimized for BioBrick use. This part is useful for breaking down chitin polymers. The strain of origin has been isolated from the Chinese honey bee and showed virulence towards Varroa destructor. Chitinases A and B from the strain were found to have miticidal activity. ChiA has both exochitinase and endochitinase activity. This protein is known to show synergistic activity with ChiB. ChiA can potentially be used to control Varroa destructor mite populations, as mite mortality increases when the mites are subjected to filter paper incubated with purified chiA.
false
false
_2380_
29556
29556
9
false
This sequence was optimized using the IDT codon optimization tool. Multiple restriction sites were removed; BsaI at position 195, PstI at position 644, PstI at position 905 and EcoRI at position 943. Additionally, several antisense stop codons were introduced to prevent antisense transcription.
false
Lisa R??ttjers
annotation2484444
1
chiA coding region
range2484444
1
1
1695
annotation2484441
1
ATG start codon
range2484441
1
1
3
annotation2484442
1
TAA stop codon
range2484442
1
1690
1692
annotation2484443
1
TAA stop codon
range2484443
1
1693
1695
BBa_I0500
1
pBad/araC
Inducible pBad/araC promoter
2003-12-05T12:00:00Z
2015-08-31T04:07:29Z
-- No description --
false
true
_1_
0
24
7
In stock
false
true
Sri Kosuri
annotation1498843
1
AraC
range1498843
1
1
1079
annotation1498842
1
PC
range1498842
1
1043
1114
annotation1498841
1
Pbad
range1498841
1
1080
1210
BBa_B0012
1
BBa_B0012
TE from coliphageT7
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Derived from the TE terminator of T7 bacteriophage between Genes 1.3 and 1.4 <genbank>V01146</genbank>.
Released HQ 2013
Transcription terminator for the <i>E.coli</i> RNA polymerase.
false
false
_1_
0
24
7
In stock
false
<P> <P>Suggested by Sri Kosuri and Drew Endy as a high efficiency terminator. The 5' end cutoff was placed immediately after the TAA stop codon and the 3' end cutoff was placed just prior to the RBS of Gene 1.4 (before AAGGAG).<P> Use anywhere transcription should be stopped when the gene of interest is upstream of this terminator.
false
Reshma Shetty
annotation7020
1
BBa_B0012
range7020
1
1
41
annotation1687
1
stop
range1687
1
34
34
annotation1690
1
polya
range1690
1
28
41
annotation1686
1
T7 TE
range1686
1
8
27
BBa_B0015
1
BBa_B0015
double terminator (B0010-B0012)
2003-07-16T11:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
Double terminator consisting of BBa_B0010 and BBa_B0012
false
true
_1_
0
24
7
In stock
false
true
Reshma Shetty
component1916612
1
BBa_B0012
component1916610
1
BBa_B0010
annotation1916612
1
BBa_B0012
range1916612
1
89
129
annotation1916610
1
BBa_B0010
range1916610
1
1
80
BBa_B0010_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctc
BBa_K1913002_sequence
1
ttatgacaacttgacggctacatcattcactttttcttcacaaccggcacggaactcgctcgggctggccccggtgcattttttaaatacccgcgagaaatagagttgatcgtcaaaaccaacattgcgaccgacggtggcgataggcatccgggtggtgctcaaaagcagcttcgcctggctgatacgttggtcctcgcgccagcttaagacgctaatccctaactgctggcggaaaagatgtgacagacgcgacggcgacaagcaaacatgctgtgcgacgctggcgatatcaaaattgctgtctgccaggtgatcgctgatgtactgacaagcctcgcgtacccgattatccatcggtggatggagcgactcgttaatcgcttccatgcgccgcagtaacaattgctcaagcagatttatcgccagcagctccgaatagcgcccttccccttgcccggcgttaatgatttgcccaaacaggtcgctgaaatgcggctggtgcgcttcatccgggcgaaagaaccccgtattggcaaatattgacggccagttaagccattcatgccagtaggcgcgcggacgaaagtaaacccactggtgataccattcgcgagcctccggatgacgaccgtagtgatgaatctctcctggcgggaacagcaaaatatcacccggtcggcaaacaaattctcgtccctgatttttcaccaccccctgaccgcgaatggtgagattgagaatataacctttcattcccagcggtcggtcgataaaaaaatcgagataaccgttggcctcaatcggcgttaaacccgccaccagatgggcattaaacgagtatcccggcagcaggggatcattttgcgcttcagccatacttttcatactcccgccattcagagaagaaaccaattgtccatattgcatcagacattgccgtcactgcgtcttttactggctcttctcgctaaccaaaccggtaaccccgcttattaaaagcattctgtaacaaagcgggaccaaagccatgacaaaaacgcgtaacaaaagtgtctataatcacggcagaaaagtccacattgattatttgcacggcgtcacactttgctatgccatagcatttttatccataagattagcggatcctacctgacgctttttatcgcaactctctactgtttctccatacccgtttttttgggctagctactagagtcacacaggaaagtactagatgcgcaagttcaataaaccccttctggctttgctgatcggctcaaccctttgctcagccgcgcaagcggctgcaccggggaaaccaactattgcttgggggaatactaaattcgctatcgttgaagtggaccaggcagccacggcttataataatcttgttaaggtaaaaaatgcggcagacgtctcggtaagttggaatttgtggaatggggatgccggtacaacagcaaaaatcctgttgaacggtaaggaagcctggagcggcccgtcaactggatcgtcaggaaccgcgaacttcaaggtcaacaagggcggacgttatcaaatgcaggtcgctctttgcaacgccgacggatgcacggcaagtgacgccaccgaaatcgtagttgctgatacggacggctcccacttggccccccttaaagagcctttacttgagaagaacaaaccttataagcaaaattttggcaaagttgtaggtagttattttgtagagtggggcgtatatggacgtaacttcactgtggataaaattccagcccaaaatttgacccacttgttgtatggatttattcctatttgcggcgggaacggaatcaatgactccctgaaggagattgaaggctcatttcaagctttgcagcgttcctgtcagggccgcgaggactttaaagtctcaatccacgatcctttcgcagctatgcaaaaggcccagaaaggagtcacggcttgggatgatccatataagggcaactttggtcagctgatggctctgaaacaggcgcgtcccgatttgaaaattttgcccagcattggaggatggacgctgtccgacccgttcttctttatgggcgataaggttaaacgcgaccgttttgtaggttcagtaaaggagttcctgcaaacctggaagttctttgatggggtagatattgattgggagtttcctggtgggaagggcgctaatccaaacctgggctctcctcaggacggagaaacctatgttcttttgatgaaagagctgcgcgccatgttggaccaattatccgtggaaactgggcgcaaatatgaactgacttctgctatctctgccggtaaggacaagattgataaggtcgcatataacgttgcccagaactcgatggatcacgtatttcttatgtcttacgatttttatggcgcattcgatttgaagaatcttgggcaccagactgcccttaacgcccctgcttggaaacccgataccgcctacactacggttaatggcgtaaatgcgctgttggctcagggcgtcactccaggaaaaatcgttgtaggaacggcaatgtatggccgtggttggacaggtgtcaatgggtaccagaacaatatcccgtttacgggcacggctacgggcccggttaaaggcacgtgggagaacgggatcgtagactaccgccaaatcgctagtcaatttatgtccggcgaatggcagtatacttatgatgccactgcggaggcaccctatgtcttcaagccgtctactggggatctgatcaccttcgacgatgcacgctccgtccaggccaaggggaaatacgtgcttgacaaacagttaggcggattgtttagctgggaaattgacgcggataacggcgatattcttaactctatgaatgcctcgttaggaaattccgcaggggtgcaataataatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_B0032_sequence
1
tcacacaggaaag
BBa_K1913000_sequence
1
atgcgcaagttcaataaaccccttctggctttgctgatcggctcaaccctttgctcagccgcgcaagcggctgcaccggggaaaccaactattgcttgggggaatactaaattcgctatcgttgaagtggaccaggcagccacggcttataataatcttgttaaggtaaaaaatgcggcagacgtctcggtaagttggaatttgtggaatggggatgccggtacaacagcaaaaatcctgttgaacggtaaggaagcctggagcggcccgtcaactggatcgtcaggaaccgcgaacttcaaggtcaacaagggcggacgttatcaaatgcaggtcgctctttgcaacgccgacggatgcacggcaagtgacgccaccgaaatcgtagttgctgatacggacggctcccacttggccccccttaaagagcctttacttgagaagaacaaaccttataagcaaaattttggcaaagttgtaggtagttattttgtagagtggggcgtatatggacgtaacttcactgtggataaaattccagcccaaaatttgacccacttgttgtatggatttattcctatttgcggcgggaacggaatcaatgactccctgaaggagattgaaggctcatttcaagctttgcagcgttcctgtcagggccgcgaggactttaaagtctcaatccacgatcctttcgcagctatgcaaaaggcccagaaaggagtcacggcttgggatgatccatataagggcaactttggtcagctgatggctctgaaacaggcgcgtcccgatttgaaaattttgcccagcattggaggatggacgctgtccgacccgttcttctttatgggcgataaggttaaacgcgaccgttttgtaggttcagtaaaggagttcctgcaaacctggaagttctttgatggggtagatattgattgggagtttcctggtgggaagggcgctaatccaaacctgggctctcctcaggacggagaaacctatgttcttttgatgaaagagctgcgcgccatgttggaccaattatccgtggaaactgggcgcaaatatgaactgacttctgctatctctgccggtaaggacaagattgataaggtcgcatataacgttgcccagaactcgatggatcacgtatttcttatgtcttacgatttttatggcgcattcgatttgaagaatcttgggcaccagactgcccttaacgcccctgcttggaaacccgataccgcctacactacggttaatggcgtaaatgcgctgttggctcagggcgtcactccaggaaaaatcgttgtaggaacggcaatgtatggccgtggttggacaggtgtcaatgggtaccagaacaatatcccgtttacgggcacggctacgggcccggttaaaggcacgtgggagaacgggatcgtagactaccgccaaatcgctagtcaatttatgtccggcgaatggcagtatacttatgatgccactgcggaggcaccctatgtcttcaagccgtctactggggatctgatcaccttcgacgatgcacgctccgtccaggccaaggggaaatacgtgcttgacaaacagttaggcggattgtttagctgggaaattgacgcggataacggcgatattcttaactctatgaatgcctcgttaggaaattccgcaggggtgcaataataa
BBa_I0500_sequence
1
ttatgacaacttgacggctacatcattcactttttcttcacaaccggcacggaactcgctcgggctggccccggtgcattttttaaatacccgcgagaaatagagttgatcgtcaaaaccaacattgcgaccgacggtggcgataggcatccgggtggtgctcaaaagcagcttcgcctggctgatacgttggtcctcgcgccagcttaagacgctaatccctaactgctggcggaaaagatgtgacagacgcgacggcgacaagcaaacatgctgtgcgacgctggcgatatcaaaattgctgtctgccaggtgatcgctgatgtactgacaagcctcgcgtacccgattatccatcggtggatggagcgactcgttaatcgcttccatgcgccgcagtaacaattgctcaagcagatttatcgccagcagctccgaatagcgcccttccccttgcccggcgttaatgatttgcccaaacaggtcgctgaaatgcggctggtgcgcttcatccgggcgaaagaaccccgtattggcaaatattgacggccagttaagccattcatgccagtaggcgcgcggacgaaagtaaacccactggtgataccattcgcgagcctccggatgacgaccgtagtgatgaatctctcctggcgggaacagcaaaatatcacccggtcggcaaacaaattctcgtccctgatttttcaccaccccctgaccgcgaatggtgagattgagaatataacctttcattcccagcggtcggtcgataaaaaaatcgagataaccgttggcctcaatcggcgttaaacccgccaccagatgggcattaaacgagtatcccggcagcaggggatcattttgcgcttcagccatacttttcatactcccgccattcagagaagaaaccaattgtccatattgcatcagacattgccgtcactgcgtcttttactggctcttctcgctaaccaaaccggtaaccccgcttattaaaagcattctgtaacaaagcgggaccaaagccatgacaaaaacgcgtaacaaaagtgtctataatcacggcagaaaagtccacattgattatttgcacggcgtcacactttgctatgccatagcatttttatccataagattagcggatcctacctgacgctttttatcgcaactctctactgtttctccatacccgtttttttgggctagc
BBa_B0012_sequence
1
tcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_B0015_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z