BBa_K192001
1
BBa_K192001
CFP +tgt +lva
2009-09-14T11:00:00Z
2015-05-08T01:11:15Z
Part was synthesized.
CFP with targeting sequence and LVA tag. The targeting sequence targets the protein to the encapsulin nanocompartment [1] with the aim of increasing the half-life of the protein. LVA should help limit the amount of background activity.
[1] M. Sutter, et al., "Structural basis of enzyme encapsulation into a bacterial nanocompartment," Nat. Struct. & Mol. Biol., vol. 15, pp. 939-47., 2008.
false
false
_297_
0
2231
9
Not in stock
false
We decided to position the LVA at the C-terminus of the construct since that is its natural position. However, the tgt extension sequence is also typically found at the C-terminus, so we're hoping that the shorter LVA sequence won't interfere too much with the binding with encapsulin. If necessary, it'll be possible to remove the LVA tag via PCR.
false
Daniel Wong, Kenny Zhan, Jason An
annotation2020960
1
double stop
range2020960
1
853
858
annotation2020963
1
lva
range2020963
1
820
852
annotation2020962
1
tgt
range2020962
1
718
819
annotation2020961
1
cfp
range2020961
1
4
717
annotation2020959
1
start
range2020959
1
1
3
BBa_K192001_sequence
1
atggtgagcaagggcgaggagctgttcaccggggtggtgcccatcctggtcgagctggacggcgacgtgaacggccacaagttcagcgtgtccggcgagggcgagggcgatgccacctacggcaagctgaccctgaagttcatctgcaccaccggcaagctgcccgtgccctggcccaccctcgtgaccaccctgacctggggcgtgcagtgcttcagccgctaccccgaccacatgaagcagcacgacttcttcaagtccgccatgcccgaaggctacgtccaggagcgcaccatcttcttcaaggacgacggcaactacaagacccgcgccgaggtgaagttcgagggcgacaccctggtgaaccgcatcgagctgaagggcatcgacttcaaggaggacggcaacatcctggggcacaagctggagtacaactacatcagccacaacgtctatatcaccgccgacaagcagaagaacggcatcaaggccaacttcaagatccgccacaacatcgaggacggcagcgtgcagctcgccgaccactaccagcagaacacccccatcggcgacggccccgtgctgctgcccgacaaccactacctgagcacccagtccgccctgagcaaagaccccaacgagaagcgcgatcacatggtcctgctggagttcgtgaccgccgccgggatcactctcggcatggacgagctgtacaagctcagaacttacctgttcacggacaagccgatcacagaaatcgaagaagaaacgtccggtggatcagaaaacacgggtggagacctcggcataaggaagctcgctgcaaacgacgaaaactacgctttagtagcttaataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z